PDB 4kiq

PDB Information

PDB4KIQ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
The Identification of Novel P38-Alpha Isoform Selective Kinase Inhibitors Having an Unprecedented P38-Alpha Binding Mode
Wrobleski, S.T., Lin, S., Murali Dhar, T.G., Dyckman, A.J., Li, T., Pitt, S., Zhang, R., Fan, Y., Doweyko, A.M., Tokarski, J.S., Kish, K.F., Kiefer, S.E., Sack, J.S., Newitt, J.A., Witmer, M.R., McKinnon, M., Barrish, J.C., Dodd, J.H., Schieven, G.L., Leftheris, K.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2013-05-02
Resolution2.500
CATH Insert Date07 Jul, 2013

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 08 Jul, 2013 Chopped
B 08 Jul, 2013 Chopped
C 08 Jul, 2013 Chopped
D 08 Jul, 2013 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4kiqA01 09 Aug, 2013 3.30.200.20 Assigned
4kiqA02 09 Aug, 2013 1.10.510.10 Assigned
4kiqB01 09 Aug, 2013 3.30.200.20 Assigned
4kiqB02 09 Aug, 2013 1.10.510.10 Assigned
4kiqC01 09 Aug, 2013 3.30.200.20 Assigned
4kiqC02 09 Aug, 2013 1.10.510.10 Assigned
4kiqD01 09 Aug, 2013 3.30.200.20 Assigned
4kiqD02 09 Aug, 2013 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q16539 MK14_HUMAN Homo sapiens Mitogen-activated protein kinase 14
Q16539 MK14_HUMAN Homo sapiens Mitogen-activated protein kinase 14
Q16539 MK14_HUMAN Homo sapiens Mitogen-activated protein kinase 14
Q16539 MK14_HUMAN Homo sapiens Mitogen-activated protein kinase 14