PDB Information

PDB4KE5
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHepatitis C virus
Primary Citation
Discovery of a Potent Boronic Acid Derived Inhibitor of the HCV RNA-Dependent RNA Polymerase.
Maynard, A., Crosby, R.M., Ellis, B., Hamatake, R., Hong, Z., Johns, B.A., Kahler, K.M., Koble, C., Leivers, A., Leivers, M.R., Mathis, A., Peat, A.J., Pouliot, J.J., Roberts, C.D., Samano, V., Schmidt, R.M., Smith, G.K., Spaltenstein, A., Stewart, E.L., Thommes, P., Turner, E.M., Voitenleitner, C., Walker, J.T., Waitt, G., Weatherhead, J., Weaver, K., Williams, S., Wright, L., Xiong, Z.Z., Haigh, D., Shotwell, J.B.
J.Med.Chem.
HeaderReplication/Replication Inhibitor
Released2013-04-25
Resolution2.110
CATH Insert Date07 Jul, 2013

PDB Images (11)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 08 Jul, 2013 Chopped
B 08 Jul, 2013 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4ke5A01 08 Oct, 2013 Holding pen
4ke5A02 08 Oct, 2013 Holding pen
4ke5A03 08 Oct, 2013 3.30.70.270 Assigned
4ke5A04 08 Oct, 2013 Holding pen
4ke5B01 08 Oct, 2013 Holding pen
4ke5B02 08 Oct, 2013 Holding pen
4ke5B03 08 Oct, 2013 3.30.70.270 Assigned
4ke5B04 08 Oct, 2013 Holding pen

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P26663 POLG_HCVBK Hepatitis C virus (isolate BK) Genome polyprotein
P26663 POLG_HCVBK Hepatitis C virus (isolate BK) Genome polyprotein