PDB 4jzf

PDB Information

PDB4JZF
MethodX-RAY DIFFRACTION
Host OrganismCricetinae
Gene SourceHomo sapiens
Primary Citation
Discovery of nonbenzamidine factor VIIa inhibitors using a biaryl acid scaffold.
Bolton, S.A., Sutton, J.C., Anumula, R., Bisacchi, G.S., Jacobson, B., Slusarchyk, W.A., Treuner, U.D., Wu, S.C., Zhao, G., Pi, Z., Sheriff, S., Smirk, R.A., Bisaha, S., Cheney, D.L., Wei, A., Schumacher, W.A., Hartl, K.S., Liu, E., Zahler, R., Seiler, S.M.
Bioorg.Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2013-04-02
Resolution1.840
CATH Insert Date01 Sep, 2013

PDB Images (6)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
H 02 Sep, 2013 Chopped
L 02 Sep, 2013 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
4jzfH01 26 Oct, 2013 2.40.10.10 Assigned
4jzfH02 26 Oct, 2013 2.40.10.10 Assigned
4jzfL00 10 Sep, 2013 2.10.25.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P08709 FA7_HUMAN Homo sapiens Coagulation factor VII
P08709 FA7_HUMAN Homo sapiens Coagulation factor VII