PDB 4ibc

PDB Information

PDB4IBC
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceEbola virus
Primary Citation
In Silico Derived Small Molecules Bind the Filovirus VP35 Protein and Inhibit Its Polymerase Cofactor Activity.
Brown, C.S., Lee, M.S., Leung, D.W., Wang, T., Xu, W., Luthra, P., Anantpadma, M., Shabman, R.S., Melito, L.M., Macmillan, K.S., Borek, D.M., Otwinowski, Z., Ramanan, P., Stubbs, A.J., Peterson, D.S., Binning, J.M., Tonelli, M., Olson, M.A., Davey, R.A., Ready, J.M., Basler, C.F., Amarasinghe, G.K.
J.Mol.Biol.
HeaderTranscription/Transcription Inhibitor
Released2012-12-08
Resolution1.750
CATH Insert Date23 Mar, 2014

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 24 Mar, 2014 Chopped
B 24 Mar, 2014 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4ibcA01 25 Apr, 2014 1.10.8.950 Assigned
4ibcA02 25 Apr, 2014 2.10.10.70 Assigned
4ibcB01 25 Apr, 2014 1.10.8.950 Assigned
4ibcB02 25 Apr, 2014 2.10.10.70 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q05127 VP35_EBOZM Ebola virus - Mayinga, Zaire, 1976 Polymerase cofactor VP35
Q05127 VP35_EBOZM Ebola virus - Mayinga, Zaire, 1976 Polymerase cofactor VP35