PDB Information

PDB4GMC
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHepatitis C virus
Primary Citation
Allosteric N-acetamide-indole-6-carboxylic acid thumb pocket 1 inhibitors of hepatitis C virus NS5B polymerase - Acylsulfonamides and acylsulfamides as carboxylic acid replacements
Beaulieu, P.L., Coulombe, R., Gillard, J., Brochu, C., Duan, J., Garneau, M., Jolicoeur, E., Kuhn, P., Poupart, M.A., Rancourt, J., Stammers, T.A., Thavonekham, B., Kukolj, G.
Can.J.Chem.
HeaderTransferase/Transferase Inhibitor
Released2012-08-15
Resolution2.700
CATH Insert Date28 Mar, 2013

PDB Images (9)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 28 Mar, 2013 Chopped
B 28 Mar, 2013 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
4gmcA01 08 Oct, 2013 Holding pen
4gmcA02 08 Oct, 2013 Holding pen
4gmcB01 25 Sep, 2013 Holding pen
4gmcB02 25 Sep, 2013 Holding pen
4gmcB03 25 Sep, 2013 3.30.70.270 Assigned
4gmcB04 25 Sep, 2013 Holding pen

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O92972 POLG_HCVJ4 Hepatitis C virus isolate HC-J4 Genome polyprotein
O92972 POLG_HCVJ4 Hepatitis C virus isolate HC-J4 Genome polyprotein