PDB Information

PDB4GDY
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery of Hydroxamate Bioisosteres as KATII Inhibitors with Improved Oral Bioavailability and Pharmacokinetics
Verhoest, P.R., Henderson, J.L., Sawant-Basak, A., Tuttle, J.B., Dounay, A.B., McAllister, L.A., Pandit, J., Rong, S., Hou, X., Bechle, B., Parikh, V., Evrard, E., Ghosh, S., Salafia, M.A., Rago, B., Obach, R., Fonseca, K.R., Chang, C.
MEDCHEMCOMM
HeaderTransferase/Transferase Inhibitor
Released2012-08-01
Resolution2.890
CATH Insert Date04 Nov, 2012

PDB Images (9)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped
B 05 Nov, 2012 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
4gdyA01 30 Aug, 2013 Holding pen
4gdyA02 30 Aug, 2013 3.40.640.10 Assigned
4gdyA03 30 Aug, 2013 3.90.1150.10 Assigned
4gdyB01 30 Aug, 2013 Holding pen
4gdyB02 30 Aug, 2013 3.40.640.10 Assigned
4gdyB03 30 Aug, 2013 3.90.1150.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q8N5Z0 AADAT_HUMAN Homo sapiens Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
Q8N5Z0 AADAT_HUMAN Homo sapiens Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial
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