PDB Information

PDB4DJZ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Monospecific Inhibitors Show That Both Mannan-binding Lectin-associated Serine Protease-1 (MASP-1) and -2 Are Essential for Lectin Pathway Activation and Reveal Structural Plasticity of MASP-2.
Heja, D., Harmat, V., Fodor, K., Wilmanns, M., Dobo, J., Kekesi, K.A., Zavodszky, P., Gal, P., Pal, G.
J.Biol.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2012-02-03
Resolution3.200
CATH Insert Date27 May, 2012

PDB Images (15)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 28 May, 2012 Chopped
B 28 May, 2012 Chopped
C 28 May, 2012 Chopped
D 28 May, 2012 Chopped
H 28 May, 2012 Rejected
I 28 May, 2012 Rejected

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4djzA01 08 Jun, 2012 2.10.70.10 Assigned
4djzA02 08 Jun, 2012 2.10.70.10 Assigned
4djzB01 08 Jun, 2012 2.40.10.10 Assigned
4djzB02 08 Jun, 2012 2.40.10.10 Assigned
4djzC01 08 Jun, 2012 2.10.70.10 Assigned
4djzC02 08 Jun, 2012 2.10.70.10 Assigned
4djzD01 08 Jun, 2012 2.40.10.10 Assigned
4djzD02 08 Jun, 2012 2.40.10.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P48740 MASP1_HUMAN Homo sapiens Mannan-binding lectin serine protease 1
P48740 MASP1_HUMAN Homo sapiens Mannan-binding lectin serine protease 1
P48740 MASP1_HUMAN Homo sapiens Mannan-binding lectin serine protease 1
P48740 MASP1_HUMAN Homo sapiens Mannan-binding lectin serine protease 1