CATH Domain 4djzD02

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.40	Beta Barrel
	2.40.10	Thrombin, subunit H
	2.40.10.10	Trypsin-like serine proteases

Domain Context

CATH Clusters

Superfamily	Trypsin-like serine proteases
Functional Family

Enzyme Information

3.4.21.-

Serine endopeptidases.

based on mapping to UniProt P48740

UniProtKB Entries (1)

MASP1_HUMAN

Homo sapiens

Mannan-binding lectin serine protease 1

PDB Structure

PDB	4DJZ
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Monospecific Inhibitors Show That Both Mannan-binding Lectin-associated Serine Protease-1 (MASP-1) and -2 Are Essential for Lectin Pathway Activation and Reveal Structural Plasticity of MASP-2. Heja, D., Harmat, V., Fodor, K., Wilmanns, M., Dobo, J., Kekesi, K.A., Zavodszky, P., Gal, P., Pal, G. J.Biol.Chem.