PDB Information

PDB4DG4
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Presence versus absence of hydrogen bond donor Tyr-39 influences interactions of cationic trypsin and mesotrypsin with protein protease inhibitors.
Salameh, M.A., Soares, A.S., Alloy, A., Radisky, E.S.
Protein Sci.
HeaderHydrolase/Hydrolase Inhibitor
Released2012-01-24
Resolution1.400
CATH Insert Date04 Nov, 2012

PDB Images (21)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 05 Nov, 2012 Chopped
B 05 Nov, 2012 Chopped
C 05 Nov, 2012 Chopped
D 05 Nov, 2012 Chopped
E 05 Nov, 2012 Chopped
F 05 Nov, 2012 Chopped
G 05 Nov, 2012 Chopped
H 05 Nov, 2012 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
4dg4A01 10 Nov, 2012 2.40.10.10 Assigned
4dg4A02 10 Nov, 2012 2.40.10.10 Assigned
4dg4B01 10 Nov, 2012 2.40.10.10 Assigned
4dg4B02 10 Nov, 2012 2.40.10.10 Assigned
4dg4C00 08 Feb, 2013 4.10.410.10 Assigned
4dg4D01 10 Nov, 2012 2.40.10.10 Assigned
4dg4D02 10 Nov, 2012 2.40.10.10 Assigned
4dg4E00 08 Feb, 2013 4.10.410.10 Assigned
4dg4F00 08 Feb, 2013 4.10.410.10 Assigned
4dg4G01 10 Nov, 2012 2.40.10.10 Assigned
4dg4G02 10 Nov, 2012 2.40.10.10 Assigned
4dg4H00 08 Feb, 2013 4.10.410.10 Assigned

UniProtKB Entries (8)

Accession Gene ID Taxon Description
P00974 BPT1_BOVIN Bos taurus Pancreatic trypsin inhibitor
P00974 BPT1_BOVIN Bos taurus Pancreatic trypsin inhibitor
P35030 TRY3_HUMAN Homo sapiens Trypsin-3
P35030 TRY3_HUMAN Homo sapiens Trypsin-3
P35030 TRY3_HUMAN Homo sapiens Trypsin-3
P00974 BPT1_BOVIN Bos taurus Pancreatic trypsin inhibitor
P35030 TRY3_HUMAN Homo sapiens Trypsin-3
P00974 BPT1_BOVIN Bos taurus Pancreatic trypsin inhibitor