CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.10 | Thrombin, subunit H |
|
2.40.10.10 | Trypsin-like serine proteases |
Domain Context
CATH Clusters
| Superfamily | Trypsin-like serine proteases |
| Functional Family | Anionic trypsin-2 |
Enzyme Information
| 3.4.21.4 |
Trypsin.
based on mapping to UniProt P35030
Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.
-!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.4.
|
UniProtKB Entries (2)
| P00974 |
BPT1_BOVIN
Bos taurus
Pancreatic trypsin inhibitor
|
| P35030 |
TRY3_HUMAN
Homo sapiens
Trypsin-3
|
PDB Structure
| PDB | 4DG4 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Presence versus absence of hydrogen bond donor Tyr-39 influences interactions of cationic trypsin and mesotrypsin with protein protease inhibitors.
Protein Sci.
|