PDB 4c7k

PDB Links
Overview

PDB Information

PDB	4C7K
Method	X-RAY DIFFRACTION
Host Organism	ESCHERICHIA COLI
Gene Source	HOMO SAPIENS
Primary Citation	Optimization of Brain Penetrant 11Beta-Hydroxysteroid Dehydrogenase Type I Inhibitors and in Vivo Testing in Diet- Induced Obese Mice. Goldberg, F.W., Dossetter, A.G., Scott, J.S., Robb, G.R., Boyd, S., Groombridge, S.D., Kemmitt, P.D., Sjogren, T., Gutierrez, P.M., Deschoolmeester, J., Swales, J.G., Turnbull, A.V., Wild, M.J. J.Med.Chem.
Header	Oxidoreductase
Released	2013-09-23
Resolution	1.910
CATH Insert Date	09 Mar, 2014

PDB Images (9)

Image of CATH 4c7k

4c7k

PDB 4c7k

Image of CATH 4c7kA

4c7kA

PDB Chain 4c7kA

Image of CATH 4c7kB

4c7kB

PDB Chain 4c7kB

Image of CATH 4c7kC

4c7kC

PDB Chain 4c7kC

Image of CATH 4c7kD

4c7kD

PDB Chain 4c7kD

Image of CATH 4c7kA00

4c7kA00

CATH Domain 4c7kA00

Image of CATH 4c7kB00

4c7kB00

CATH Domain 4c7kB00

Image of CATH 4c7kC00

4c7kC00

CATH Domain 4c7kC00

Image of CATH 4c7kD00

4c7kD00

CATH Domain 4c7kD00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	10 Mar, 2014	Chopped
B	10 Mar, 2014	Chopped
C	10 Mar, 2014	Chopped
D	10 Mar, 2014	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4c7kA00	25 Apr, 2014	3.40.50.720	Assigned
4c7kB00	25 Apr, 2014	3.40.50.720	Assigned
4c7kC00	25 Apr, 2014	3.40.50.720	Assigned
4c7kD00	25 Apr, 2014	3.40.50.720	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1