PDB 4ajw

PDB Information

PDB4AJW
MethodX-RAY DIFFRACTION
Host OrganismSPODOPTERA FRUGIPERDA
Gene SourceMUS MUSCULUS
Primary Citation
Discovery and Optimization of New Benzimidazole- and Benzoxazole-Pyrimidone Selective Pi3Kbeta Inhibitors for the Treatment of Phosphatase and Tensin Homologue (Pten)-Deficient Cancers.
Certal, V., Halley, F., Virone-Oddos, A., Delorme, C., Karlsson, A., Rak, A., Thompson, F., Filoche-Romm, B., El-Ahmad, Y., Carry, J.C., Abecassis, P.Y., Lejeune, P., Vincent, L., Bonnevaux, H., Nicolas, J.P., Bertrand, T., Marquette, J.P., Michot, N., Benard, T., Below, P., Vade, I., Chatreaux, F., Lebourg, G., Pilorge, F., Angouillant-Boniface, O., Louboutin, A., Lengauer, C., Schio, L.
J.Med.Chem.
HeaderTransferase
Released2012-02-20
Resolution2.800
CATH Insert Date27 May, 2012

PDB Images (13)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 28 May, 2012 Chopped
B 28 May, 2012 Chopped

CATH Domains (10)

Domain ID Date inserted into CATH Superfamily CATH Status
4ajwA01 15 Nov, 2013 3.10.20.90 Assigned
4ajwA02 15 Nov, 2013 Cathedral cath submit
4ajwA03 15 Nov, 2013 1.25.40.70 Assigned
4ajwA04 15 Nov, 2013 3.30.1010.10 Assigned
4ajwA05 15 Nov, 2013 1.10.1070.11 Assigned
4ajwB01 10 Oct, 2013 1.25.40.70 Assigned
4ajwB02 10 Oct, 2013 3.10.20.90 Assigned
4ajwB03 10 Oct, 2013 2.60.40.150 Assigned
4ajwB04 10 Oct, 2013 3.30.1010.10 Assigned
4ajwB05 10 Oct, 2013 1.10.1070.11 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O35904 PK3CD_MOUSE Mus musculus Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
O35904 PK3CD_MOUSE Mus musculus Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform