PDB 4a6l

PDB Information

PDB4A6L
MethodX-RAY DIFFRACTION
Host OrganismPICHIA PASTORIS
Gene SourceHOMO SAPIENS
Primary Citation
Structure-Based Library Design and the Discovery of a Potent and Selective Mast Cell Beta-Tryptase Inhibitor as an Oral Therapeutic Agent.
Liang, G., Aldous, S., Merriman, G., Levell, J., Pribish, J., Cairns, J., Chen, X., Maignan, S., Mathieu, M., Tsay, J., Sides, K., Rebello, S., Whitely, B., Morize, I., Pauls, H.W.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2011-11-04
Resolution2.050
CATH Insert Date29 Jan, 2012

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 30 Jan, 2012 Chopped
B 30 Jan, 2012 Chopped
C 30 Jan, 2012 Chopped
D 30 Jan, 2012 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4a6lA01 02 Feb, 2012 2.40.10.10 Assigned
4a6lA02 02 Feb, 2012 2.40.10.10 Assigned
4a6lB01 02 Feb, 2012 2.40.10.10 Assigned
4a6lB02 02 Feb, 2012 2.40.10.10 Assigned
4a6lC01 02 Feb, 2012 2.40.10.10 Assigned
4a6lC02 02 Feb, 2012 2.40.10.10 Assigned
4a6lD01 01 Feb, 2012 2.40.10.10 Assigned
4a6lD02 01 Feb, 2012 2.40.10.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q15661 TRYB1_HUMAN Homo sapiens Tryptase alpha/beta-1
Q15661 TRYB1_HUMAN Homo sapiens Tryptase alpha/beta-1
Q15661 TRYB1_HUMAN Homo sapiens Tryptase alpha/beta-1
Q15661 TRYB1_HUMAN Homo sapiens Tryptase alpha/beta-1