PDB Information

PDB3UWO
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourcePseudomonas aeruginosa
Primary Citation
Structure guided development of novel thymidine mimetics targeting Pseudomonas aeruginosa thymidylate kinase: from hit to lead generation.
Choi, J.Y., Plummer, M.S., Starr, J., Desbonnet, C.R., Soutter, H., Chang, J., Miller, J.R., Dillman, K., Miller, A.A., Roush, W.R.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2011-12-02
Resolution1.700
CATH Insert Date05 Feb, 2012

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 06 Feb, 2012 Chopped
B 06 Feb, 2012 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3uwoA00 09 Feb, 2012 3.40.50.300 Assigned
3uwoB00 09 Feb, 2012 3.40.50.300 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q9HZN8 KTHY_PSEAE Pseudomonas aeruginosa PAO1 Thymidylate kinase
Q9HZN8 KTHY_PSEAE Pseudomonas aeruginosa PAO1 Thymidylate kinase