PDB Information

PDB3KMC
MethodX-RAY DIFFRACTION
Host OrganismTrichoplusia ni
Gene SourceHomo sapiens
Primary Citation
The discovery of novel tartrate-based TNF-alpha converting enzyme (TACE) inhibitors.
Rosner, K.E., Guo, Z., Orth, P., Shipps, G.W., Belanger, D.B., Chan, T.Y., Curran, P.J., Dai, C., Deng, Y., Girijavallabhan, V.M., Hong, L., Lavey, B.J., Lee, J.F., Li, D., Liu, Z., Popovici-Muller, J., Ting, P.C., Vaccaro, H., Wang, L., Wang, T., Yu, W., Zhou, G., Niu, X., Sun, J., Kozlowski, J.A., Lundell, D.J., Madison, V., McKittrick, B., Piwinski, J.J., Shih, N.Y., Arshad Siddiqui, M., Strickland, C.O.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2009-11-10
Resolution1.800
CATH Insert Date24 Dec, 2009

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 25 Dec, 2009 Chopped
B 25 Dec, 2009 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
3kmcA00 19 Apr, 2010 3.40.390.10 Assigned
3kmcB00 19 Apr, 2010 3.40.390.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P78536 ADA17_HUMAN Homo sapiens Disintegrin and metalloproteinase domain-containing protein 17
P78536 ADA17_HUMAN Homo sapiens Disintegrin and metalloproteinase domain-containing protein 17