PDB Information

PDB3IS9
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHuman immunodeficiency virus type 1 BH10
Primary Citation
Crystallographic study of a novel subnanomolar inhibitor provides insight on the binding interactions of alkenyldiarylmethanes with human immunodeficiency virus-1 reverse transcriptase.
Cullen, M.D., Ho, W.C., Bauman, J.D., Das, K., Arnold, E., Hartman, T.L., Watson, K.M., Buckheit, R.W., Pannecouque, C., De Clercq, E., Cushman, M.
J.Med.Chem.
HeaderTransferase/Hydrolase
Released2009-08-25
Resolution2.550
CATH Insert Date11 Apr, 2010

PDB Images (12)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 11 Apr, 2010 Chopped
B 11 Apr, 2010 Chopped

CATH Domains (9)

Domain ID Date inserted into CATH Superfamily CATH Status
3is9A01 10 May, 2010 3.10.10.10 Assigned
3is9A02 10 May, 2010 3.30.70.270 Assigned
3is9A03 10 May, 2010 3.30.70.270 Assigned
3is9A04 10 May, 2010 3.30.70.270 Assigned
3is9A05 10 May, 2010 3.30.420.10 Assigned
3is9B01 10 May, 2010 3.10.10.10 Assigned
3is9B02 10 May, 2010 3.30.70.270 Assigned
3is9B03 10 May, 2010 3.30.70.270 Assigned
3is9B04 10 May, 2010 3.30.70.270 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P03366 POL_HV1B1 Human immunodeficiency virus type 1 BH10 Gag-Pol polyprotein
P03366 POL_HV1B1 Human immunodeficiency virus type 1 BH10 Gag-Pol polyprotein
CATH-Gene3D is a Global Biodata Core Resource Learn more...