PDB Information

PDB3H5U
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHepatitis C virus
Primary Citation
Non-nucleoside inhibitors of HCV polymerase NS5B. Part 4: structure-based design, synthesis, and biological evaluation of benzo[d]isothiazole-1,1-dioxides
de Vicente, J., Hendricks, R.T., Smith, D.B., Fell, J.B., Fischer, J., Spencer, S.R., Stengel, P.J., Mohr, P., Robinson, J.E., Blake, J.F., Hilgenkamp, R.K., Yee, C., Adjabeng, G., Elworthy, T.R., Li, J., Wang, B., Bamberg, J.T., Harris, S.F., Wong, A., Leveque, V.J., Najera, I., Le Pogam, S., Rajyaguru, S., Ao-Ieong, G., Alexandrova, L., Larrabee, S., Brandl, M., Briggs, A., Sukhtankar, S., Farrell, R.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2009-04-22
Resolution1.950
CATH Insert Date10 Sep, 2009

PDB Images (11)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 10 Sep, 2009 Chopped
B 10 Sep, 2009 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
3h5uA01 03 Oct, 2013 Holding pen
3h5uA02 03 Oct, 2013 Holding pen
3h5uA03 03 Oct, 2013 3.30.70.270 Assigned
3h5uA04 03 Oct, 2013 Holding pen
3h5uB01 03 Oct, 2013 Holding pen
3h5uB02 03 Oct, 2013 Holding pen
3h5uB03 03 Oct, 2013 3.30.70.270 Assigned
3h5uB04 03 Oct, 2013 Holding pen

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P26663 POLG_HCVBK Hepatitis C virus (isolate BK) Genome polyprotein
P26663 POLG_HCVBK Hepatitis C virus (isolate BK) Genome polyprotein