PDB Information

PDB3GW5
MethodX-RAY DIFFRACTION
Host OrganismHomo sapiens
Gene SourceHomo sapiens
Primary Citation
Design and optimization of renin inhibitors: Orally bioavailable alkyl amines.
Tice, C.M., Xu, Z., Yuan, J., Simpson, R.D., Cacatian, S.T., Flaherty, P.T., Zhao, W., Guo, J., Ishchenko, A., Singh, S.B., Wu, Z., Scott, B.B., Bukhtiyarov, Y., Berbaum, J., Mason, J., Panemangalore, R., Cappiello, M.G., Muller, D., Harrison, R.K., McGeehan, G.M., Dillard, L.W., Baldwin, J.J., Claremon, D.A.
Bioorg.Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2009-03-31
Resolution2.000
CATH Insert Date16 Aug, 2009

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 16 Aug, 2009 Chopped
B 16 Aug, 2009 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3gw5A01 20 Jan, 2010 2.40.70.10 Assigned
3gw5A02 20 Jan, 2010 2.40.70.10 Assigned
3gw5B01 19 Jan, 2010 2.40.70.10 Assigned
3gw5B02 19 Jan, 2010 2.40.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P00797 RENI_HUMAN Homo sapiens Renin
P00797 RENI_HUMAN Homo sapiens Renin