PDB 3g49

PDB Information

PDB3G49
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceCavia porcellus
Primary Citation
N-(Pyridin-2-yl) arylsulfonamide inhibitors of 11beta-hydroxysteroid dehydrogenase type 1: Discovery of PF-915275.
Siu, M., Johnson, T.O., Wang, Y., Nair, S.K., Taylor, W.D., Cripps, S.J., Matthews, J.J., Edwards, M.P., Pauly, T.A., Ermolieff, J., Castro, A., Hosea, N.A., LaPaglia, A., Fanjul, A.N., Vogel, J.E.
Bioorg.Med.Chem.Lett.
HeaderOxidoreductase/Oxidoreductase Inhibitor
Released2009-02-03
Resolution2.500
CATH Insert Date16 Aug, 2009

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 16 Aug, 2009 Chopped
B 16 Aug, 2009 Chopped
C 16 Aug, 2009 Chopped
D 16 Aug, 2009 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
3g49A00 13 Dec, 2009 3.40.50.720 Assigned
3g49B00 13 Dec, 2009 3.40.50.720 Assigned
3g49C00 13 Dec, 2009 3.40.50.720 Assigned
3g49D00 13 Dec, 2009 3.40.50.720 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q6QLL4 DHI1_CAVPO Cavia porcellus Corticosteroid 11-beta-dehydrogenase isozyme 1
Q6QLL4 DHI1_CAVPO Cavia porcellus Corticosteroid 11-beta-dehydrogenase isozyme 1
Q6QLL4 DHI1_CAVPO Cavia porcellus Corticosteroid 11-beta-dehydrogenase isozyme 1
Q6QLL4 DHI1_CAVPO Cavia porcellus Corticosteroid 11-beta-dehydrogenase isozyme 1