PDB Information

PDB3G3E
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery, SAR, and pharmacokinetics of a novel 3-Hydroxyquinolin-2(1H)-one series of potent D-amino acid oxidase (DAAO) inhibitors
Duplantier, A.J., Becker, S.L., Bohanon, M.J., Borzilleri, K.A., Chrunyk, B.A., Downs, J.T., Hu, L.Y., El-Kattan, A., James, L.C., Liu, S., Lu, J., Maklad, N., Mansour, M.N., Mente, S., Piotrowski, M.A., Sakya, S.M., Sheehan, S., Steyn, S.J., Strick, C.A., Williams, V.A., Zhang, L.
J.Med.Chem.
HeaderOxidoreductase
Released2009-02-02
Resolution2.200
CATH Insert Date16 Aug, 2009

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 16 Aug, 2009 Chopped
B 16 Aug, 2009 Chopped
C 16 Aug, 2009 Chopped
D 16 Aug, 2009 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
3g3eA01 13 Dec, 2009 3.40.50.720 Assigned
3g3eA02 13 Dec, 2009 3.30.9.10 Assigned
3g3eB01 13 Dec, 2009 3.40.50.720 Assigned
3g3eB02 13 Dec, 2009 3.30.9.10 Assigned
3g3eC01 13 Dec, 2009 3.40.50.720 Assigned
3g3eC02 13 Dec, 2009 3.30.9.10 Assigned
3g3eD01 13 Dec, 2009 3.40.50.720 Assigned
3g3eD02 13 Dec, 2009 3.30.9.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P14920 OXDA_HUMAN Homo sapiens D-amino-acid oxidase
P14920 OXDA_HUMAN Homo sapiens D-amino-acid oxidase
P14920 OXDA_HUMAN Homo sapiens D-amino-acid oxidase
P14920 OXDA_HUMAN Homo sapiens D-amino-acid oxidase