PDB 3fl9
PDB Information
| PDB | 3FL9 |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli |
| Gene Source | Bacillus anthracis |
| Primary Citation | Crystal structure of Bacillus anthracis dihydrofolate reductase with the dihydrophthalazine-based trimethoprim derivative RAB1 provides a structural explanation of potency and selectivity.
Antimicrob.Agents Chemother.
|
| Header | Oxidoreductase |
| Released | 2008-12-18 |
| Resolution | 2.400 |
| CATH Insert Date | 16 Aug, 2009 |
PDB Images (17)
3fl9
PDB 3fl9
3fl9A
PDB Chain 3fl9A
3fl9B
PDB Chain 3fl9B
3fl9C
PDB Chain 3fl9C
3fl9D
PDB Chain 3fl9D
3fl9E
PDB Chain 3fl9E
3fl9F
PDB Chain 3fl9F
3fl9G
PDB Chain 3fl9G
3fl9H
PDB Chain 3fl9H
3fl9A00
CATH Domain 3fl9A00
3fl9B00
CATH Domain 3fl9B00
3fl9C00
CATH Domain 3fl9C00
3fl9D00
CATH Domain 3fl9D00
3fl9E00
CATH Domain 3fl9E00
3fl9F00
CATH Domain 3fl9F00
3fl9G00
CATH Domain 3fl9G00
3fl9H00
CATH Domain 3fl9H00
PDB Prints
PDB Chains (8)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 16 Aug, 2009 | Chopped |
| B | 16 Aug, 2009 | Chopped |
| C | 16 Aug, 2009 | Chopped |
| D | 16 Aug, 2009 | Chopped |
| E | 16 Aug, 2009 | Chopped |
| F | 16 Aug, 2009 | Chopped |
| G | 16 Aug, 2009 | Chopped |
| H | 16 Aug, 2009 | Chopped |
CATH Domains (8)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 3fl9A00 | 06 Dec, 2009 | 3.40.430.10 | Assigned |
| 3fl9B00 | 06 Dec, 2009 | 3.40.430.10 | Assigned |
| 3fl9C00 | 06 Dec, 2009 | 3.40.430.10 | Assigned |
| 3fl9D00 | 06 Dec, 2009 | 3.40.430.10 | Assigned |
| 3fl9E00 | 06 Dec, 2009 | 3.40.430.10 | Assigned |
| 3fl9F00 | 06 Dec, 2009 | 3.40.430.10 | Assigned |
| 3fl9G00 | 06 Dec, 2009 | 3.40.430.10 | Assigned |
| 3fl9H00 | 06 Dec, 2009 | 3.40.430.10 | Assigned |
UniProtKB Entries (8)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| Q81R22 | Q81R22_BACAN | Bacillus anthracis | Dihydrofolate reductase |
| Q81R22 | Q81R22_BACAN | Bacillus anthracis | Dihydrofolate reductase |
| Q81R22 | Q81R22_BACAN | Bacillus anthracis | Dihydrofolate reductase |
| Q81R22 | Q81R22_BACAN | Bacillus anthracis | Dihydrofolate reductase |
| Q81R22 | Q81R22_BACAN | Bacillus anthracis | Dihydrofolate reductase |
| Q81R22 | Q81R22_BACAN | Bacillus anthracis | Dihydrofolate reductase |
| Q81R22 | Q81R22_BACAN | Bacillus anthracis | Dihydrofolate reductase |
| Q81R22 | Q81R22_BACAN | Bacillus anthracis | Dihydrofolate reductase |