PDB Information

PDB3EOB
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Efalizumab binding to the LFA-1 alphaL I domain blocks ICAM-1 binding via steric hindrance.
Li, S., Wang, H., Peng, B., Zhang, M., Zhang, D., Hou, S., Guo, Y., Ding, J.
Proc.Natl.Acad.Sci.USA
HeaderImmune System/Cell Adhesion
Released2008-09-26
Resolution3.600
CATH Insert Date16 Aug, 2009

PDB Images (17)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 16 Aug, 2009 Chopped
B 16 Aug, 2009 Chopped
H 16 Aug, 2009 Chopped
I 16 Aug, 2009 Chopped
J 16 Aug, 2009 Chopped
L 16 Aug, 2009 Chopped

CATH Domains (10)

Domain ID Date inserted into CATH Superfamily CATH Status
3eobA01 18 May, 2010 2.60.40.10 Assigned
3eobA02 18 May, 2010 2.60.40.10 Assigned
3eobB01 18 May, 2010 2.60.40.10 Assigned
3eobB02 18 May, 2010 2.60.40.10 Assigned
3eobH01 18 May, 2010 2.60.40.10 Assigned
3eobH02 18 May, 2010 2.60.40.10 Assigned
3eobI00 29 Sep, 2009 3.40.50.410 Assigned
3eobJ00 29 Sep, 2009 3.40.50.410 Assigned
3eobL01 18 May, 2010 2.60.40.10 Assigned
3eobL02 18 May, 2010 2.60.40.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P20701 ITAL_HUMAN Homo sapiens Integrin alpha-L
P20701 ITAL_HUMAN Homo sapiens Integrin alpha-L