CATH Domain 3eobI00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.410	von Willebrand factor, type A domain

Domain Context

CATH Clusters

Superfamily	von Willebrand factor, type A domain
Functional Family

Enzyme Information

UniProtKB Entries (1)

ITAL_HUMAN

Homo sapiens

Integrin alpha-L

PDB Structure

PDB	3EOB
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Efalizumab binding to the LFA-1 alphaL I domain blocks ICAM-1 binding via steric hindrance. Li, S., Wang, H., Peng, B., Zhang, M., Zhang, D., Hou, S., Guo, Y., Ding, J. Proc.Natl.Acad.Sci.USA