PDB 2wo8

PDB Links
Overview

PDB Information

PDB	2WO8
Method	X-RAY DIFFRACTION
Host Organism	ESCHERICHIA COLI
Gene Source	HOMO SAPIENS
Primary Citation	The Identification of Beta-Hydroxy Carboxylic Acids as Selective Mmp-12 Inhibitors. Holmes, I.P., Gaines, S., Watson, S.P., Lorthioir, O., Walker, A., Baddeley, S.J., Herbert, S., Egan, D., Convery, M.A., Singh, O.M.P., Gross, J.W., Strelow, J.M., Smith, R.H., Amour, A.J., Brown, D., Martin, S.L. Bioorg.Med.Chem.Lett.
Header	Hydrolase
Released	2009-07-22
Resolution	2.000
CATH Insert Date	10 Sep, 2009

PDB Images (9)

Image of CATH 2wo8

2wo8

PDB 2wo8

Image of CATH 2wo8A

2wo8A

PDB Chain 2wo8A

Image of CATH 2wo8B

2wo8B

PDB Chain 2wo8B

Image of CATH 2wo8C

2wo8C

PDB Chain 2wo8C

Image of CATH 2wo8D

2wo8D

PDB Chain 2wo8D

Image of CATH 2wo8A00

2wo8A00

CATH Domain 2wo8A00

Image of CATH 2wo8B00

2wo8B00

CATH Domain 2wo8B00

Image of CATH 2wo8C00

2wo8C00

CATH Domain 2wo8C00

Image of CATH 2wo8D00

2wo8D00

CATH Domain 2wo8D00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	10 Sep, 2009	Chopped
B	10 Sep, 2009	Chopped
C	10 Sep, 2009	Chopped
D	10 Sep, 2009	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
2wo8A00	18 Mar, 2011	3.40.390.10	Assigned
2wo8B00	18 Mar, 2011	3.40.390.10	Assigned
2wo8C00	18 Mar, 2011	3.40.390.10	Assigned
2wo8D00	18 Mar, 2011	3.40.390.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
P39900	MMP12_HUMAN	Homo sapiens	Macrophage metalloelastase
P39900	MMP12_HUMAN	Homo sapiens	Macrophage metalloelastase
P39900	MMP12_HUMAN	Homo sapiens	Macrophage metalloelastase
P39900	MMP12_HUMAN	Homo sapiens	Macrophage metalloelastase