PDB Information

PDB2Q7N
MethodX-RAY DIFFRACTION
Host OrganismCricetulus griseus
Gene SourceMus musculus
Primary Citation
An unusual cytokine:Ig-domain interaction revealed in the crystal structure of leukemia inhibitory factor (LIF) in complex with the LIF receptor.
Huyton, T., Zhang, J.G., Luo, C.S., Lou, M.Z., Hilton, D.J., Nicola, N.A., Garrett, T.P.
Proc.Natl.Acad.Sci.USA
HeaderCytokine Receptor/Cytokine
Released2007-06-07
Resolution4.000
CATH Insert Date07 Nov, 2007

PDB Images (17)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 08 Nov, 2007 Chopped
B 08 Nov, 2007 Chopped
C 08 Nov, 2007 Chopped
D 08 Nov, 2007 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
2q7nA01 09 Sep, 2013 2.60.40.10 Assigned
2q7nA02 09 Sep, 2013 2.60.40.10 Assigned
2q7nA03 09 Sep, 2013 2.60.40.10 Assigned
2q7nA04 09 Sep, 2013 2.60.40.10 Assigned
2q7nA05 09 Sep, 2013 2.60.40.10 Assigned
2q7nB00 18 Mar, 2013 1.20.1250.10 Assigned
2q7nC01 09 Sep, 2013 2.60.40.10 Assigned
2q7nC02 09 Sep, 2013 2.60.40.10 Assigned
2q7nC03 09 Sep, 2013 2.60.40.10 Assigned
2q7nC04 09 Sep, 2013 2.60.40.10 Assigned
2q7nC05 09 Sep, 2013 2.60.40.10 Assigned
2q7nD00 18 Mar, 2013 1.20.1250.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P42703 LIFR_MOUSE Mus musculus Leukemia inhibitory factor receptor
P15018 LIF_HUMAN Homo sapiens Leukemia inhibitory factor
P42703 LIFR_MOUSE Mus musculus Leukemia inhibitory factor receptor
P15018 LIF_HUMAN Homo sapiens Leukemia inhibitory factor
CATH-Gene3D is a Global Biodata Core Resource Learn more...