CATH Classification

Domain Context

CATH Clusters

Superfamily 1.20.1250.10
Functional Family leukemia inhibitory factor

Enzyme Information

UniProtKB Entries (2)

P42703
LIFR_MOUSE
Mus musculus
Leukemia inhibitory factor receptor
P15018
LIF_HUMAN
Homo sapiens
Leukemia inhibitory factor

PDB Structure

PDB 2Q7N
External Links
Method X-RAY DIFFRACTION
Organism Cricetulus
Primary Citation
An unusual cytokine:Ig-domain interaction revealed in the crystal structure of leukemia inhibitory factor (LIF) in complex with the LIF receptor.
Huyton, T., Zhang, J.G., Luo, C.S., Lou, M.Z., Hilton, D.J., Nicola, N.A., Garrett, T.P.
Proc.Natl.Acad.Sci.USA
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