PDB Information

PDB2Q6B
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Design and synthesis of novel, conformationally restricted HMG-CoA reductase inhibitors.
Pfefferkorn, J.A., Choi, C., Song, Y., Trivedi, B.K., Larsen, S.D., Askew, V., Dillon, L., Hanselman, J.C., Lin, Z., Lu, G., Robertson, A., Sekerke, C., Auerbach, B., Pavlovsky, A., Harris, M.S., Bainbridge, G., Caspers, N.
Bioorg.Med.Chem.Lett.
HeaderOxidoreductase
Released2007-06-04
Resolution2.000
CATH Insert Date19 Jul, 2007

PDB Images (17)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 19 Jul, 2007 Chopped
B 19 Jul, 2007 Chopped
C 19 Jul, 2007 Chopped
D 19 Jul, 2007 Chopped

CATH Domains (12)

Domain ID Date inserted into CATH Superfamily CATH Status
2q6bA01 17 Aug, 2007 1.10.3270.10 Assigned
2q6bA02 17 Aug, 2007 3.90.770.10 Assigned
2q6bA03 17 Aug, 2007 3.30.70.420 Assigned
2q6bB01 17 Aug, 2007 1.10.3270.10 Assigned
2q6bB02 17 Aug, 2007 3.90.770.10 Assigned
2q6bB03 17 Aug, 2007 3.30.70.420 Assigned
2q6bC01 17 Aug, 2007 1.10.3270.10 Assigned
2q6bC02 17 Aug, 2007 3.90.770.10 Assigned
2q6bC03 17 Aug, 2007 3.30.70.420 Assigned
2q6bD01 17 Aug, 2007 1.10.3270.10 Assigned
2q6bD02 17 Aug, 2007 3.90.770.10 Assigned
2q6bD03 17 Aug, 2007 3.30.70.420 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase
P04035 HMDH_HUMAN Homo sapiens 3-hydroxy-3-methylglutaryl-coenzyme A reductase