PDB Information

PDB2P4I
MethodX-RAY DIFFRACTION
Host OrganismTrichoplusia ni
Gene SourceHomo sapiens
Primary Citation
Evolution of a highly selective and potent 2-(pyridin-2-yl)-1,3,5-triazine Tie-2 kinase inhibitor.
Hodous, B.L., Geuns-Meyer, S.D., Hughes, P.E., Albrecht, B.K., Bellon, S., Bready, J., Caenepeel, S., Cee, V.J., Chaffee, S.C., Coxon, A., Emery, M., Fretland, J., Gallant, P., Gu, Y., Hoffman, D., Johnson, R.E., Kendall, R., Kim, J.L., Long, A.M., Morrison, M., Olivieri, P.R., Patel, V.F., Polverino, A., Rose, P., Tempest, P., Wang, L., Whittington, D.A., Zhao, H.
J.Med.Chem.
HeaderTransferase
Released2007-03-12
Resolution2.500
CATH Insert Date22 Mar, 2007

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 22 Mar, 2007 Chopped
B 22 Mar, 2007 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
2p4iA01 10 Sep, 2008 3.30.200.20 Assigned
2p4iA02 10 Sep, 2008 1.10.510.10 Assigned
2p4iB01 10 Sep, 2008 3.30.200.20 Assigned
2p4iB02 10 Sep, 2008 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q02763 TIE2_HUMAN Homo sapiens Angiopoietin-1 receptor
Q02763 TIE2_HUMAN Homo sapiens Angiopoietin-1 receptor