PDB 1you

PDB Information

PDB1YOU
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Potent pyrimidinetrione-based inhibitors of MMP-13 with enhanced selectivity over MMP-14.
Blagg, J.A., Noe, M.C., Wolf-Gouveia, L.A., Reiter, L.A., Laird, E.R., Chang, S.P., Danley, D.E., Downs, J.T., Elliott, N.C., Eskra, J.D., Griffiths, R.J., Hardink, J.R., Haugeto, A.I., Jones, C.S., Liras, J.L., Lopresti-Morrow, L.L., Mitchell, P.G., Pandit, J., Robinson, R.P., Subramanyam, C., Vaughn-Bowser, M.L., Yocum, S.A.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2005-01-28
Resolution2.300
CATH Insert Date05 Mar, 2006

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
1youA00 10 Mar, 2006 3.40.390.10 Assigned
1youB00 10 Mar, 2006 3.40.390.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P45452 MMP13_HUMAN Homo sapiens Collagenase 3
P45452 MMP13_HUMAN Homo sapiens Collagenase 3