CATH Superfamily 3.40.50.10190

Browse Functional Families

ID	Function Family (FunFam) Name	Total Sequences	Structure?	Structural Representative	PDB Sites?	Alignment Diversity (0-100)
1	Replication factor C subunit 1	414	3D	2k7fA00	-	96.8
2	Pescadillo homolog	298	3D	2ep8A01	-	92.9
6	Breast cancer type 1 susceptibility protein homolog	248	3D	4y2gA01	-	93.7
3	Tumor suppressor p53-binding protein 1	234	3D	5ecgD01	-	90.7
5	Tumor suppressor p53-binding protein 1	211	3D	5ecgD02	-	92.4
4	DNA ligase	205		-	-	70.3
7	RNA polymerase II subunit A C-terminal domain phosphatase	177		-	-	85.4
8	X-ray repair cross complementing 1	174	3D	2d8mA01	-	93.0
10	DNA topoisomerase II binding protein 1	168	3D	3olcX03	-	98.9
9	DNA repair protein REV1	163	3D	2ebwA00	-	81.6
12	X-ray repair cross complementing 1	161	3D	3qvgD00	-	93.0
11	DNA repair protein REV1	160	3D	4id3B00	-	98.0
25	Breast cancer type 1 susceptibility protein homolog	154	3D	4y2gA02	-	92.8
13	BRCA1 associated RING domain 1	147	3D	3fa2B02	-	51.1
15	protein ECT2 isoform X1	141	3D	4n40A03	-	44.8
14	RNA polymerase II C-terminal domain phosphatase-like 3	139		-	-	91.5
16	protein ECT2 isoform X3	135	3D	4n40A02	-	51.9
17	PAX interacting protein 1	133	3D	3sqdB02	-	43.1
19	BRCA1 associated RING domain 1	130	3D	3fa2B01	-	68.0
18	DNA topoisomerase 2-binding protein 1	128	3D	3al3A01	-	96.6
20	DNA topoisomerase II binding protein 1	128	3D	3olcX02	-	95.2
21	DNA topoisomerase II binding protein 1	127	3D	3ueoD02	-	96.7
23	DNA topoisomerase II binding protein 1	114	3D	3pd7B00	-	96.3
22	DNA topoisomerase II binding protein 1	113	3D	1wf6A01	-	94.8
24	Nibrin	106		-	-	78.5
29	DNA topoisomerase II binding protein 1	102	3D	3ueoD01	-	99.3
26	DNA ligase	101		-	-	73.8
27	DNA ligase	96	3D	3ii6Y01	-	94.7
28	DNA topoisomerase 2-binding protein 1 isoform X1	95	3D	3al3A02	-	91.8
32	DNA ligase	94	3D	3qvgC00	-	88.7
33	DNA topoisomerase II binding protein 1	91	3D	3olcX01	-	89.4
30	Poly [ADP-ribose] polymerase	89	3D	2cokA00	-	87.1
31	DNA polymerase	88	3D	2jw5A00	-	97.8
35	DNA-directed DNA/RNA polymerase mu	84	3D	2htfA00	-	95.8
34	SMC5-SMC6 complex localization factor protein 1	83		-	-	25.7
36	PAX interacting protein 1	81	3D	3sqdB01	-	34.7
37	Mediator of DNA damage checkpoint protein 1	80	3D	3k05B02	-	45.2
40	Mediator of DNA damage checkpoint protein 1	69	3D	2etxB01	-	42.2
47	Microcephalin	68	3D	3u3zA01	-	73.6
38	SMC5-SMC6 complex localization factor protein 1	67		-	-	39.8
41	DNA nucleotidylexotransferase	66	3D	2coeA01	-	82.5
39	Poly [ADP-ribose] polymerase	65		-	-	71.5
42	PAX interacting protein 1	62		-	-	43.7
43	PAX interacting protein 1	57		-	-	36.0
44	DNA ligase	55		-	-	99.4
45	DNA ligase	54		-	-	81.3
46	PAX interacting protein 1	52		-	-	90.1
53	Microcephalin	51	3D	3u3zA02	-	71.1
49	RNA Polymerase II CTD phosphatase Fcp1	51	3D	4xq0A03	-	88.9
48	DNA repair protein Rtt107	50		-	-	84.7
50	DNA ligase	48	3D	3ii6Y03	-	74.3
51	Poly [ADP-ribose] polymerase	45		-	-	96.0
55	Microcephalin	41	3D	3pa6C00	-	53.0
52	Transcription coactivator	37		-	-	86.5
54	DNA ligase	34		-	-	90.3
57	Transcription coactivator	29		-	-	90.8
56	Pescadillo homolog	29		-	-	63.3
58	Epithelial cell transforming 2	28		-	-	38.8
59	ATBRCA1	27		-	-	72.2
60	G1/S regulator NimO, putative	25		-	-	82.3
62	Pebble, isoform C	25		-	-	5.1
63	Pebble, isoform B	25		-	-	56.1
61	Transcription coactivator	25		-	-	81.2
64	Protein BREAST CANCER SUSCEPTIBILITY 1 like	23		-	-	76.2
65	Poly [ADP-ribose] polymerase	23		-	-	75.9
66	BRCT domain protein Eurofung	22		-	-	81.3
67	Pescadillo homolog	21		-	-	75.0
68	Replication factor C subunit 1	20		-	-	7.4
70	Transcription coactivator	20		-	-	46.5
69	DNA ligase	20		-	-	68.6
80	S-M checkpoint control protein rad4	20	3D	6hm3A02	-	89.9
72	DNA ligase	19		-	-	71.6
91	Regulator of Ty1 transposition	19	3D	3t7kB02	-	73.2
71	Pescadillo homolog	19		-	-	7.6
73	Pescadillo homolog	18		-	-	54.0
74	DNA repair protein Rtt107	18		-	-	81.4
75	Nijmegen breakage syndrome 1 protein	18		-	-	92.6
77	Chitin biosynthesis protein CHS5	18		-	-	92.2
89	DDK kinase regulatory subunit DBF4	17	3D	3oq4E00	-	47.1
83	DNA damage repair protein Rad9	17	3D	2vxbB01	-	87.2
76	DNA helicase, phage-associated	17		-	-	0.0
78	DNA polymerase III subunit epsilon	16		-	-	31.6
79	Mutator 2, isoform B	16		-	-	14.7
81	BRCA1 C Terminus domain containing protein expressed	15		-	-	89.5
82	Os11g0191300 protein	15		-	-	41.2
86	DNA ligase	14		-	-	74.1
85	Pebble, isoform B	14		-	-	10.8
87	DNA ligase	14		-	-	15.3
84	DNA ligase	14		-	-	78.1
90	BRCA1 C Terminus domain containing protein expressed	13		-	-	55.6
88	Chitin biosynthesis protein Chs5	13		-	-	59.5
93	DNA-binding protein RAP1	13	3D	2l42A00	-	24.4
92	BRCA1-associated RING domain protein 1	12		-	-	44.7
99	DNA ligase	11		-	-	1.4
97	Kinetoplastid kinetochore protein 4	11		-	-	39.0
95	Mutator 2, isoform B	11		-	-	13.9
96	DNA repair protein REV1	11		-	-	7.5
100	DNA polymerase II complex	11		-	-	16.0
94	Regulatory subunit for Cdc7p protein kinase	11		-	-	76.6
101	Microcephalin, isoform A	11		-	-	14.7
98	Unplaced genomic scaffold supercont1.2, whole genome shotgun sequence	11		-	-	18.5
102	Rad9p	10		-	-	44.5
105	DNA ligase	10	3D	1z56C01	-	0.9
103	Pescadillo homolog	10		-	-	4.5
111	DNA polymerase II complex	9		-	-	0.0
104	DNA ligase	9		-	-	1.2
113	DNA repair protein Rtt107	9		-	-	33.4
107	RNA polymerase II subunit A domain phosphatase	9		-	-	9.2
110	Regulator of Ty1 transposition	9		-	-	5.2
109	Regulator of Ty1 transposition	9		-	-	0.9
108	Pescadillo homolog	9		-	-	78.5
112	DNA polymerase II complex	9		-	-	2.3
106	RNA polymerase II C-terminal domain phosphatase-like 4	9		-	-	43.9
119	BRCA1 C Terminus BRCT	8		-	-	35.5
118	DNA topoisomerase 2-binding protein 1-A-like Protein	8		-	-	83.7
116	Nibrin	8		-	-	37.6
117	Hypothetical_protein_-_conserved	8		-	-	41.3
114	DNA ligase	8		-	-	43.8
115	DNA polymerase POL4	8		-	-	63.2
120	WGS project CABT00000000 data, contig 2.8	7		-	-	31.2
124	DNA topoisomerase 2-binding protein 1-A	7		-	-	92.7
122	Pescadillo homolog	7		-	-	3.9
125	Replication factor C subunit 1	7		-	-	87.1
121	Poly [ADP-ribose] polymerase	7		-	-	10.3
123	DNA repair protein Rtt107	7		-	-	13.7
134	BRCT domain-containing protein	6		-	-	6.3
130	DNA repair protein REV1	6		-	-	19.3
132	DNA repair protein REV1	6		-	-	7.8
135	DNA topoisomerase II-binding protein 1	6		-	-	33.3
128	Mutagen-sensitive 101	6		-	-	11.8
129	Poly [ADP-ribose] polymerase	6		-	-	38.2
126	Epithelial cell-transforming 2	6		-	-	5.8
131	Deoxycytidyl transferase, putative	6		-	-	7.8
127	Mutagen-sensitive 101	6		-	-	13.7
133	DNA ligase	6		-	-	4.4
142	BRCT domain-containing protein	5		-	-	0.0
145	Microcephalin, isoform D	5		-	-	10.1
144	Protein CBR-HSR-9	5		-	-	25.6
140	Related to FCP1-TFIIF interacting component of CTD phosphatase	5		-	-	24.5
138	AGAP002760-PA	5		-	-	19.7
139	Nibrin	5		-	-	2.5
141	RNA Polymerase II CTD phosphatase Fcp1	5		-	-	6.2
136	DNA polymerase lambda subunit	5		-	-	13.1
143	Protein hsr-9	5		-	-	20.8
317	DNA repair protein crb2	5	3D	2vxcB02	-	0.0
137	Mutagen-sensitive 101	5		-	-	10.9
146	BRCT domain protein Eurofung	5		-	-	81.5
173	Protein CBR-MUS-101	4		-	-	74.7
307	DNA repair and telomere maintenance protein nbs1	4	3D	3hufC02	-	0.0
163	BRCT domain-containing protein	4		-	-	1.9
153	Uncharacterized protein	4		-	-	1.3
157	HSK1 kinase regulatory subunit, putative	4		-	-	2.7
167	Predicted protein	4		-	-	87.1
171	DNA ligase 3	4		-	-	88.1
161	DNA ligase	4		-	-	0.0
151	Uncharacterized protein	4		-	-	67.6
350	BRCT-containing protein 1	4	3D	3l41A01	-	0.0
166	PAX transcription activation domain interacting protein	4		-	-	7.1
156	Protein BREAST CANCER SUSCEPTIBILITY 1 homolog	4		-	-	16.8
349	BRCT-containing protein 1	4	3D	3l41A02	-	0.0
168	BRCA1 C Terminus BRCT	4		-	-	12.6
169	Protein CBG13622	4		-	-	30.4
159	Telomeric repeat-binding factor 2-interacting protein 1	4		-	-	0.0
158	Uncharacterized protein	4		-	-	11.1
165	PAX transcription activation domain interacting protein	4		-	-	6.8
155	Os05g0486600 protein	4		-	-	6.5
147	DNA ligase	4		-	-	6.2
172	DNA topoisomerase II binding protein 1	4		-	-	27.2
162	Pescadillo homolog	4		-	-	3.5
152	DNA ligase 3-like Protein	4		-	-	83.9
149	DNA ligase	4		-	-	7.5
170	Protein CBG13622	4		-	-	31.5
148	DNA ligase	4		-	-	5.9
150	DNA-directed DNA/RNA polymerase mu	4		-	-	6.0
164	PAX transcription activation domain interacting protein	4		-	-	7.6
160	DNA damage response protein RcaA	4		-	-	7.9
154	FI02888p	4		-	-	9.3
191	Transcription coactivator	3		-	-	0.0
180	DNA ligase	3		-	-	66.3
197	Protein CBR-MUS-101	3		-	-	31.2
184	DNA ligase	3		-	-	8.7
193	DNA-directed DNA/RNA polymerase mu	3		-	-	45.1
177	DNA polymerase III subunit epsilon DnaQ	3		-	-	0.0
198	Protein CBR-MUS-101	3		-	-	37.8
176	DNA ligase 4	3		-	-	0.0
185	DNA-repair protein xrcc1, putative	3		-	-	2.6
196	Protein CBR-MUS-101	3		-	-	30.3
178	Chromodomain-helicase-DNA-binding protein 1-like	3		-	-	36.0
179	NLI interacting factor-like phosphatase family protein	3		-	-	61.5
182	Poly [ADP-ribose] polymerase	3		-	-	4.3
192	Protein CBG13622	3		-	-	29.1
175	DNA ligase 4	3		-	-	0.0
186	Uncharacterized protein	3		-	-	7.7
195	DNA damage response protein Mdb1	3		-	-	77.7
189	Cell cycle checkpoint protein, putative	3		-	-	5.9
188	PAX transcription activation domain interacting protein	3		-	-	4.4
174	DNA ligase 4	3		-	-	1.1
183	Cleavage and polyadenylation factor 6-related protein	3		-	-	1.4
194	Uncharacterized protein	3		-	-	44.1
187	PAX transcription activation domain interacting protein	3		-	-	2.2
190	Uncharacterized protein	3		-	-	59.7
181	LIGase	3		-	-	21.5
202	DNA ligase	2		-	-	3.4
273	Putative dna topoisomerase 2-binding protein 1 isoform x1	2		-	-	7.2
242	Poly [ADP-ribose] polymerase	2		-	-	5.2
253	YALI0B15576p	2		-	-	0.0
280	Predicted protein	2		-	-	1.2
263	Predicted protein	2		-	-	0.0
219	Nibrin, putative	2		-	-	3.5
218	DNA ligase	2		-	-	10.0
267	DNA topoisomerase II binding protein 1	2		-	-	12.9
271	DNA topoisomerase 2-binding protein 1-A	2		-	-	0.0
224	DNA repair protein, BRCT domain	2		-	-	0.0
205	DNA polymerase	2		-	-	26.7
230	DNA ligase 4-like protein	2		-	-	2.0
234	ECT2 Mammalian Rho GEF	2		-	-	0.0
245	Nucleomorphin	2		-	-	37.1
257	PIS Pax-2, IA-1/6, Smad-2 interacting protein	2		-	-	0.0
220	DNA repair protein XRCC1	2		-	-	0.0
251	PIS Pax-2, IA-1/6, Smad-2 interacting protein	2		-	-	0.0
277	Uncharacterized protein	2		-	-	0.0
261	Chromatin-binding protein	2		-	-	0.0
216	Predicted protein	2		-	-	11.0
343	S-M checkpoint control protein rad4	2	3D	4bmdA01	-	0.0
199	DNA ligase 4	2		-	-	22.2
222	RNA polymerase II subunit A C-terminal domain phosphatase	2		-	-	0.0
217	Nibrin	2		-	-	1.1
276	Uncharacterized protein	2		-	-	2.0
232	DNA ligase	2		-	-	0.0
256	PIS Pax-2, IA-1/6, Smad-2 interacting protein	2		-	-	0.0
211	AGAP002760-PA	2		-	-	10.1
266	DNA topoisomerase 2-binding protein 1-A	2		-	-	1.4
278	Uncharacterized protein	2		-	-	0.0
240	Tumor suppressor p53-binding protein 1	2		-	-	10.0
225	AGAP003213-PA	2		-	-	0.0
204	DNA polymerase III subunit epsilon	2		-	-	0.0
279	Uncharacterized protein	2		-	-	0.0
200	DNA ligase 4	2		-	-	0.0
244	DNA ligase	2		-	-	0.0
235	ECT2 Mammalian Rho GEF	2		-	-	0.0
259	Esc4p	2		-	-	0.0
282	Uncharacterized protein	2		-	-	40.0
258	Uncharacterized protein	2		-	-	0.0
268	Putative dna topoisomerase 2-binding protein 1 isoform x1	2		-	-	6.7
269	Putative dna topoisomerase 2-binding protein 1 isoform x1	2		-	-	0.0
213	Poly [ADP-ribose] polymerase	2		-	-	27.9
228	Uncharacterized protein	2		-	-	0.0
229	CTD phosphatase-related Eurofung	2		-	-	0.0
201	DNA ligase 4	2		-	-	0.0
275	Uncharacterized protein	2		-	-	48.8
238	Cell wall chitin catabolism-related protein, putative	2		-	-	0.0
241	nibrin isoform X1	2		-	-	3.9
239	Auxin-responsive protein	2		-	-	0.0
255	PIS Pax-2, IA-1/6, Smad-2 interacting protein	2		-	-	0.0
247	DNA-repair protein XRCC1	2		-	-	8.2
342	S-M checkpoint control protein rad4	2	3D	4bmdA02	-	0.0
207	DNA-directed DNA/RNA polymerase mu	2		-	-	0.0
265	Putative dna topoisomerase 2-binding protein 1 isoform x1	2		-	-	0.0
226	RNA polymerase II subunit A C-terminal domain phosphatase-like isoform X1	2		-	-	0.0
272	Putative dna topoisomerase 2-binding protein 1 isoform x1	2		-	-	3.4
203	Replication factor C subunit 1	2		-	-	44.3
236	Uncharacterized protein	2		-	-	0.0
243	DNA ligase	2		-	-	8.6
210	YALI0D12364p	2		-	-	0.0
252	YALI0B15576p	2		-	-	0.0
214	Breast cancer type 1 susceptibility protein homolog	2		-	-	34.8
262	Chromatin-binding protein	2		-	-	1.8
274	Putative dna topoisomerase 2-binding protein 1 isoform x1	2		-	-	4.4
221	DNA repair protein XRCC1-like	2		-	-	0.0
209	DNA-directed DNA/RNA polymerase mu	2		-	-	0.0
208	Uncharacterized protein	2		-	-	0.0
231	YALI0B17006p	2		-	-	0.0
249	Uncharacterized protein	2		-	-	42.0
248	YALI0E31273p	2		-	-	0.0
270	DNA topoisomerase 2-binding protein 1-A	2		-	-	0.0
237	Uncharacterized protein	2		-	-	0.0
254	YALI0B15576p	2		-	-	0.0
283	DNA topoisomerase II-binding protein 1	2		-	-	51.0
260	Uncharacterized protein	2		-	-	0.0
264	DNA topoisomerase 2-binding protein 1-A	2		-	-	0.0
227	Uncharacterized protein	2		-	-	0.0
212	Uncharacterized protein	2		-	-	19.4
250	YALI0B15576p	2		-	-	0.0
223	Poly [ADP-ribose] polymerase	2		-	-	0.0
206	DNA polymerase	2		-	-	8.9
246	Uncharacterized protein	2		-	-	3.7
233	FHA domain containing protein, putative	2		-	-	0.0
281	Uncharacterized protein	2		-	-	38.8
215	Uncharacterized protein	2		-	-	12.4
355	Uncharacterized protein	1		-	-	0.0
347	ADL145Cp	1		-	-	0.0
291	Predicted protein	1		-	-	0.0
365	BRCT domain protein Eurofung	1		-	-	0.0
328	DNA ligase	1		-	-	0.0
297	Uncharacterized protein	1		-	-	0.0
329	DNA-directed DNA/RNA polymerase mu	1		-	-	0.0
301	DNA ligase	1		-	-	0.0
284	DNA ligase	1		-	-	0.0
338	Uncharacterized protein	1		-	-	0.0
341	Uncharacterized protein	1		-	-	0.0
339	Pescadillo homolog	1		-	-	0.0
352	BRCT-containing protein 1	1		-	-	0.0
310	Nbs	1		-	-	0.0
314	Uncharacterized protein	1		-	-	0.0
362	Predicted protein	1		-	-	0.0
293	Probable DNA polymerase III polC-type	1		-	-	0.0
326	Uncharacterized protein	1		-	-	0.0
303	DNA ligase	1		-	-	0.0
336	Predicted protein	1		-	-	0.0
337	Uncharacterized protein	1		-	-	0.0
354	DNA damage response protein Mdb1	1		-	-	0.0
360	Uncharacterized protein	1		-	-	0.0
364	Uncharacterized protein	1		-	-	0.0
327	Uncharacterized protein	1		-	-	0.0
299	DNA ligase	1		-	-	0.0
312	Predicted protein	1		-	-	0.0
298	DNA topoisomerase 2-binding protein 1-A-like Protein	1		-	-	0.0
321	AGAP002605-PA	1		-	-	0.0
309	Uncharacterized protein	1		-	-	0.0
285	DNA ligase 4	1		-	-	0.0
308	Predicted protein	1		-	-	0.0
331	Uncharacterized protein	1		-	-	0.0
348	Uncharacterized protein	1		-	-	0.0
370	Uncharacterized protein	1		-	-	0.0
296	DNA topoisomerase 2-binding protein 1-A-like Protein	1		-	-	0.0
315	Predicted protein	1		-	-	0.0
323	Uncharacterized protein	1		-	-	0.0
306	Uncharacterized protein	1		-	-	0.0
333	Breast cancer type 1 susceptibility protein homolog	1		-	-	0.0
346	Uncharacterized protein	1		-	-	0.0
353	Uncharacterized protein	1		-	-	0.0
292	DNA ligase 4	1		-	-	0.0
319	Nibrin	1		-	-	0.0
363	Uncharacterized protein	1		-	-	0.0
318	Uncharacterized protein	1		-	-	0.0
286	DNA ligase 4	1		-	-	0.0
302	Uncharacterized protein	1		-	-	0.0
351	Uncharacterized protein	1		-	-	0.0
361	Uncharacterized protein	1		-	-	0.0
295	Uncharacterized protein	1		-	-	0.0
316	BRCA1-associated RING domain protein 1	1		-	-	0.0
367	Predicted protein	1		-	-	0.0
289	DNA ligase 4	1		-	-	0.0
324	Uncharacterized protein	1		-	-	0.0
305	Uncharacterized protein	1		-	-	0.0
288	DNA ligase	1		-	-	0.0
330	Uncharacterized protein	1		-	-	0.0
334	DNA ligase	1		-	-	0.0
345	ADL145Cp	1		-	-	0.0
320	Uncharacterized protein	1		-	-	0.0
357	Predicted protein	1		-	-	0.0
356	Uncharacterized protein	1		-	-	0.0
311	Predicted protein	1		-	-	0.0
366	Uncharacterized protein	1		-	-	0.0
322	Uncharacterized protein	1		-	-	0.0
332	Predicted protein	1		-	-	0.0
290	DNA ligase 4	1		-	-	0.0
359	Predicted protein	1		-	-	0.0
358	Uncharacterized protein	1		-	-	0.0
368	Uncharacterized protein	1		-	-	0.0
294	Pol lambda-related class X DNA repair polymerase	1		-	-	0.0
287	Uncharacterized protein	1		-	-	0.0
313	Nibrin	1		-	-	0.0
369	Uncharacterized protein	1		-	-	0.0
340	Pescadillo homolog	1		-	-	0.0
325	Uncharacterized protein	1		-	-	0.0
304	Uncharacterized protein	1		-	-	0.0
300	Replication factor C subunit 1	1		-	-	0.0
344	Uncharacterized protein	1		-	-	0.0
335	Meiotically up-regulated gene 176 protein	1		-	-	0.0

Network disruptions

Functional Families

Browse Functional Families