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1 keywords

CATH Domain 3u3zA01

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.10190 BRCT domain

Domain Context

CATH Clusters

Superfamily BRCT domain
Functional Family Microcephalin

Enzyme Information

UniProtKB Entries (1)

P16104
H2AX_HUMAN
Homo sapiens
Histone H2AX

PDB Structure

PDB 3U3Z
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Dual recognition of phosphoserine and phosphotyrosine in histone variant H2A.X by DNA damage response protein MCPH1.
Singh, N., Basnet, H., Wiltshire, T.D., Mohammad, D.H., Thompson, J.R., Heroux, A., Botuyan, M.V., Yaffe, M.B., Couch, F.J., Rosenfeld, M.G., Mer, G.
Proc.Natl.Acad.Sci.USA
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