The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Toll/interleukin-1 receptor homology (TIR) domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
SC:1X-linked interleukin-1 receptor accessory protein-like 1Myeloid differentiation primary response protein MyD88TIR domain-containing adapter molecule 1SC:2Disease resistance protein (TIR-NBS-LRR class)phosphoinositide 3-kinase adapter protein 1Toll/interleukin-1 receptor domain-containing adapter proteinDisease resistance protein (TIR-NBS-LRR class)Uncharacterized proteinToll-like receptor 2Interleukin 1 receptor accessory proteinToll-like receptor 7Toll-like receptor 4Toll-like receptor 3X-linked interleukin-1 receptor accessory protein-like 1single Ig IL-1-related receptor isoform X1Sterile alpha and TIR motif-containing proteinSterile alpha and TIR motif containing 1TIR domain-containing adapter molecule 2Disease resistance protein (TIR-NBS class)B cell scaffold protein with ankyrin repeats 1p-loop containing nucleoside triphosphate hydrolase superfamily protein18w proteinBlast:Protein tollToll receptor 13Myd88Sterile alpha and TIR motif-containing protein tir-1Toll-like receptor 2Toll-6Protein kinase family proteinTOLl (Drosophila) familyToll-like receptor 5bputative ST2L protein isoform X4AGAP001590-PBToll-4TehaoSterile alpha and TIR motif containing 1Disease resistance protein (TIR-NBS-LRR class) familyinterleukin-18 receptor 1 isoform X3Putative serine/threonine-protein kinase pats1Uncharacterized proteinToll-like receptor 1Phosphoinositide-3-kinase adaptor protein 1Disease resistance protein CHS1Toll-like receptor adaptor molecule 1Uncharacterized proteinPutative phosphoinositide 3-kinase adapter protein 1Uncharacterized proteinUncharacterized proteinInterleukin-1 receptor type IUncharacterized proteinUncharacterized proteinPredicted proteinUncharacterized proteinToll-like receptor2Uncharacterized proteinUncharacterized proteinDisease resistance protein (TIR-NBS-LRR class) familyPutative serine/threonine-protein kinase pats1Disease resistance protein (TIR-NBS class)Toll-Interleukin receptorTransmembrane receptors / ATP binding proteinPredicted proteinInterleukin 1 receptor accessory proteinUncharacterized protein PHLOEM PROTEIN 2-LIKE A7Uncharacterized proteinUncharacterized proteinUncharacterized proteinToll-like receptor 9Uncharacterized proteinToll-like receptor 19Uncharacterized proteinUncharacterized proteinUncharacterized proteinMyeloid differentiation factor 88Uncharacterized proteinTIR-domain containing adaptor inducing INF-betaUncharacterized proteinInterleukin 1 receptor accessory protein-like 2Uncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinProtein CBG03616Uncharacterized proteinProtein tirAUncharacterized proteinUncharacterized proteinPredicted proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized protein
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FunFam 16: Disease resistance protein (TIR-NBS class)

There are 0 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

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