The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Cytidine Deaminase, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 3: COP9 signalosome complex subunit 5

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 14 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
53 O35864 (/IPI) O94454 (/IPI) P91001 (/IPI) Q54PF3 (/IPI) Q5BBF1 (/IPI) Q8LAZ7 (/IPI) Q8LAZ7 (/IPI) Q92905 (/IPI) Q92905 (/IPI) Q92905 (/IPI)
(43 more)
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
44 O35864 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS)
(34 more)
Translation initiation factor activity GO:0003743
Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
43 Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS)
(33 more)
Thiol-dependent ubiquitin-specific protease activity GO:0004843
Catalysis of the thiol-dependent hydrolysis of a peptide bond formed by the C-terminal glycine of ubiquitin and another protein.
43 Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA)
(33 more)
Metallopeptidase activity GO:0008237
Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
43 Q92905 (/IMP) Q92905 (/IMP) Q92905 (/IMP) Q92905 (/IMP) Q92905 (/IMP) Q92905 (/IMP) Q92905 (/IMP) Q92905 (/IMP) Q92905 (/IMP) Q92905 (/IMP)
(33 more)
NEDD8-specific protease activity GO:0019784
Catalysis of the hydrolysis of NEDD8, a small ubiquitin-related modifier, from previously neddylated substrates.
43 Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS)
(33 more)
NEDD8-specific protease activity GO:0019784
Catalysis of the hydrolysis of NEDD8, a small ubiquitin-related modifier, from previously neddylated substrates.
3 O94454 (/IDA) Q9XZ58 (/IDA) Q9XZ58 (/IDA)
Metalloendopeptidase activity GO:0004222
Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
1 Q5BBF1 (/TAS)
Thiol-dependent ubiquitin-specific protease activity GO:0004843
Catalysis of the thiol-dependent hydrolysis of a peptide bond formed by the C-terminal glycine of ubiquitin and another protein.
1 O35864 (/ISO)
Protein C-terminus binding GO:0008022
Interacting selectively and non-covalently with a protein C-terminus, the end of any peptide chain at which the 1-carboxyl function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
1 P91001 (/IPI)
Metallopeptidase activity GO:0008237
Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
1 O35864 (/ISO)
DEAD/H-box RNA helicase binding GO:0017151
Interacting selectively and non-covalently with the enzyme DEAD/H-box RNA helicase.
1 P91001 (/IPI)
Enzyme binding GO:0019899
Interacting selectively and non-covalently with any enzyme.
1 O35864 (/IPI)
Macrophage migration inhibitory factor binding GO:0035718
Interacting selectively and non-covalently with the cytokine, macrophage migration inhibitory factor.
1 O35864 (/IPI)

There are 64 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein deneddylation GO:0000338
The removal of a ubiquitin-like protein of the NEDD8 type from a protein.
49 O94454 (/IMP) Q59PG6 (/IMP) Q8LAZ7 (/IMP) Q8LAZ7 (/IMP) Q92905 (/IMP) Q92905 (/IMP) Q92905 (/IMP) Q92905 (/IMP) Q92905 (/IMP) Q92905 (/IMP)
(39 more)
Protein deneddylation GO:0000338
The removal of a ubiquitin-like protein of the NEDD8 type from a protein.
43 Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA)
(33 more)
Nucleotide-excision repair, DNA damage recognition GO:0000715
The identification of lesions in DNA, such as pyrimidine-dimers, intrastrand cross-links, and bulky adducts. The wide range of substrate specificity suggests the repair complex recognizes distortions in the DNA helix.
43 Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS)
(33 more)
Transcription-coupled nucleotide-excision repair GO:0006283
The nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the global genome nucleotide excision repair pathway.
43 Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS)
(33 more)
Transcription by RNA polymerase II GO:0006366
The synthesis of RNA from a DNA template by RNA polymerase II (RNAP II), originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).
43 Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS)
(33 more)
Translation GO:0006412
The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA or circRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA or circRNA. Translation ends with the release of a polypeptide chain from the ribosome.
43 Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS)
(33 more)
Protein deubiquitination GO:0016579
The removal of one or more ubiquitin groups from a protein.
43 Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA)
(33 more)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
43 Q92905 (/IMP) Q92905 (/IMP) Q92905 (/IMP) Q92905 (/IMP) Q92905 (/IMP) Q92905 (/IMP) Q92905 (/IMP) Q92905 (/IMP) Q92905 (/IMP) Q92905 (/IMP)
(33 more)
Post-translational protein modification GO:0043687
The process of covalently altering one or more amino acids in a protein after the protein has been completely translated and released from the ribosome.
43 Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS)
(33 more)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
43 Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA)
(33 more)
Regulation of JNK cascade GO:0046328
Any process that modulates the frequency, rate or extent of signal transduction mediated by the JNK cascade.
43 Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA)
(33 more)
Positive regulation of DNA-binding transcription factor activity GO:0051091
Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
43 Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA)
(33 more)
Regulation of IRE1-mediated unfolded protein response GO:1903894
Any process that modulates the frequency, rate or extent of the IRE1-mediated unfolded protein response.
43 Q92905 (/IMP) Q92905 (/IMP) Q92905 (/IMP) Q92905 (/IMP) Q92905 (/IMP) Q92905 (/IMP) Q92905 (/IMP) Q92905 (/IMP) Q92905 (/IMP) Q92905 (/IMP)
(33 more)
Exosomal secretion GO:1990182
The process whereby a membrane-bounded vesicle is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane.
43 Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA)
(33 more)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
4 O35864 (/ISS) Q6GLM9 (/ISS) Q6P635 (/ISS) Q6PC30 (/ISS)
Positive regulation of DNA-binding transcription factor activity GO:0051091
Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
4 O35864 (/ISS) Q6GLM9 (/ISS) Q6P635 (/ISS) Q6PC30 (/ISS)
Protein deneddylation GO:0000338
The removal of a ubiquitin-like protein of the NEDD8 type from a protein.
3 Q5BBF1 (/TAS) Q8LAZ7 (/TAS) Q8LAZ7 (/TAS)
Response to auxin GO:0009733
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus.
3 Q8LAZ7 (/IGI) Q8LAZ7 (/IGI) Q9FVU9 (/IGI)
Negative regulation of photomorphogenesis GO:0010100
Any process that stops, reduces or prevents photomorphogenesis.
3 Q8LAZ7 (/IGI) Q8LAZ7 (/IGI) Q9FVU9 (/IGI)
COP9 signalosome assembly GO:0010387
The aggregation, arrangement and bonding together of a set of components to form a COP9 signalosome.
3 Q8LAZ7 (/IMP) Q8LAZ7 (/IMP) Q9FVU9 (/IMP)
Positive regulation of G2/M transition of mitotic cell cycle GO:0010971
Any signalling pathway that activates or increases the activity of a cell cycle cyclin-dependent protein kinase to modulate the switch from G2 phase to M phase of the mitotic cell cycle.
3 Q8LAZ7 (/IMP) Q8LAZ7 (/IMP) Q9FVU9 (/IMP)
Protein deneddylation GO:0000338
The removal of a ubiquitin-like protein of the NEDD8 type from a protein.
2 P91001 (/IGI) Q9FVU9 (/IGI)
Compound eye photoreceptor cell differentiation GO:0001751
The process in which a relatively unspecialized cell acquires the specialized features of an eye photoreceptor cell.
2 Q9XZ58 (/IMP) Q9XZ58 (/IMP)
Compound eye photoreceptor cell differentiation GO:0001751
The process in which a relatively unspecialized cell acquires the specialized features of an eye photoreceptor cell.
2 Q9XZ58 (/TAS) Q9XZ58 (/TAS)
Multicellular organism development GO:0007275
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
2 Q9XZ58 (/IMP) Q9XZ58 (/IMP)
Germ cell development GO:0007281
The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism.
2 Q9XZ58 (/IMP) Q9XZ58 (/IMP)
Oocyte dorsal/ventral axis specification GO:0007310
The establishment, maintenance and elaboration of the dorsal/ventral axis of the oocyte. An example of this is found in Drosophila melanogaster.
2 Q9XZ58 (/IMP) Q9XZ58 (/IMP)
Oocyte anterior/posterior axis specification GO:0007314
Polarization of the oocyte along its anterior-posterior axis. An example of this is found in Drosophila melanogaster.
2 Q9XZ58 (/IMP) Q9XZ58 (/IMP)
Axonogenesis GO:0007409
De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells.
2 Q9XZ58 (/IMP) Q9XZ58 (/IMP)
Glial cell migration GO:0008347
The orderly movement of a glial cell, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system.
2 Q9XZ58 (/IMP) Q9XZ58 (/IMP)
Activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c GO:0008635
Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process and is mediated by cytochrome c.
2 A7TX80 (/IDA) F2Z540 (/IDA)
Specification of floral organ identity GO:0010093
The process in which the identity of a floral organ primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
2 Q8LAZ7 (/IMP) Q8LAZ7 (/IMP)
Regulation of defense response GO:0031347
Any process that modulates the frequency, rate or extent of a defense response.
2 Q8LAZ7 (/IMP) Q8LAZ7 (/IMP)
Negative regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032435
Any process that stops, prevents, or reduces the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
2 Q9XZ58 (/IMP) Q9XZ58 (/IMP)
Negative regulation of lamellocyte differentiation GO:0035204
Any process that stops, prevents, or reduces the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes.
2 Q9XZ58 (/IMP) Q9XZ58 (/IMP)
Negative regulation of hemocyte proliferation GO:0035207
Any process that stops, prevents or reduces the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster.
2 Q9XZ58 (/IMP) Q9XZ58 (/IMP)
Female germ-line stem cell population maintenance GO:0036099
The process by which an organism or tissue maintains a population of female germ-line stem cells.
2 Q9XZ58 (/IMP) Q9XZ58 (/IMP)
Positive regulation of apoptotic process GO:0043065
Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
2 A7TX80 (/IDA) F2Z540 (/IDA)
Positive regulation of cell cycle GO:0045787
Any process that activates or increases the rate or extent of progression through the cell cycle.
2 Q9XZ58 (/IMP) Q9XZ58 (/IMP)
Male germ-line cyst encapsulation GO:0048140
Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the male gonad.
2 Q9XZ58 (/IMP) Q9XZ58 (/IMP)
Germarium-derived cystoblast division GO:0048142
The four rounds of incomplete mitosis undergone by a cystoblast to form a 16-cell cyst of interconnected cells within a germarium. Within the cyst, one cell differentiates into an oocyte while the rest become nurse cells. An example of this process is found in Drosophila melanogaster.
2 Q9XZ58 (/IMP) Q9XZ58 (/IMP)
Oogenesis GO:0048477
The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.
2 Q9XZ58 (/TAS) Q9XZ58 (/TAS)
Protein stabilization GO:0050821
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
2 Q9XZ58 (/IMP) Q9XZ58 (/IMP)
Positive regulation of cellular protein catabolic process GO:1903364
Any process that activates or increases the frequency, rate or extent of cellular protein catabolic process.
2 Q9XZ58 (/IMP) Q9XZ58 (/IMP)
Reproduction GO:0000003
The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms.
1 P91001 (/IMP)
Protein deneddylation GO:0000338
The removal of a ubiquitin-like protein of the NEDD8 type from a protein.
1 O35864 (/ISO)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
1 O35864 (/TAS)
Gonad development GO:0008406
The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones.
1 P91001 (/IMP)
Protein deubiquitination GO:0016579
The removal of one or more ubiquitin groups from a protein.
1 O35864 (/ISO)
Asexual reproduction GO:0019954
The biological process in which new individuals are produced by either a single cell or a group of cells, in the absence of any sexual process.
1 Q54PF3 (/IMP)
Hyphal growth GO:0030448
Growth of fungi as threadlike, tubular structures that may contain multiple nuclei and may or may not be divided internally by septa, or cross-walls.
1 Q5BBF1 (/IMP)
Negative regulation of apoptotic process GO:0043066
Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
1 O35864 (/ISO)
Protein neddylation GO:0045116
Covalent attachment of the ubiquitin-like protein NEDD8 (RUB1) to another protein.
1 Q5BBF1 (/IMP)
Positive regulation of protein catabolic process GO:0045732
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
1 Q9FVU9 (/IMP)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 O35864 (/ISO)
Regulation of JNK cascade GO:0046328
Any process that modulates the frequency, rate or extent of signal transduction mediated by the JNK cascade.
1 O35864 (/ISO)
Oogenesis GO:0048477
The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.
1 P91001 (/IMP)
Positive regulation of DNA-binding transcription factor activity GO:0051091
Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
1 O35864 (/ISO)
Regulation of cell cycle GO:0051726
Any process that modulates the rate or extent of progression through the cell cycle.
1 O35864 (/IMP)
Vestibular receptor cell development GO:0060118
The process whose specific outcome is the progression of a vestibular receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
1 Q6PC30 (/IMP)
Cleistothecium development GO:0070791
The process whose specific outcome is the progression of the cleistothecium over time, from its formation to the mature structure. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.
1 Q5BBF1 (/IMP)
Regulation of IRE1-mediated unfolded protein response GO:1903894
Any process that modulates the frequency, rate or extent of the IRE1-mediated unfolded protein response.
1 O35864 (/ISO)
Exosomal secretion GO:1990182
The process whereby a membrane-bounded vesicle is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane.
1 O35864 (/ISO)
Regulation of L-ascorbic acid biosynthetic process GO:2000082
Any process that modulates the frequency, rate or extent of L-ascorbic acid biosynthetic process.
1 Q9FVU9 (/IMP)

There are 31 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
87 A0A024R7W9 (/IDA) A0A024R7W9 (/IDA) A0A024R7W9 (/IDA) A0A024R7W9 (/IDA) A0A024R7W9 (/IDA) A0A024R7W9 (/IDA) A0A024R7W9 (/IDA) A0A024R7W9 (/IDA) A0A024R7W9 (/IDA) A0A024R7W9 (/IDA)
(77 more)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
86 A0A024R7W9 (/IDA) A0A024R7W9 (/IDA) A0A024R7W9 (/IDA) A0A024R7W9 (/IDA) A0A024R7W9 (/IDA) A0A024R7W9 (/IDA) A0A024R7W9 (/IDA) A0A024R7W9 (/IDA) A0A024R7W9 (/IDA) A0A024R7W9 (/IDA)
(76 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
48 A7TX80 (/IDA) F2Z540 (/IDA) P91001 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA)
(38 more)
COP9 signalosome GO:0008180
A protein complex that catalyzes the deneddylation of proteins, including the cullin component of SCF ubiquitin E3 ligase; deneddylation increases the activity of cullin family ubiquitin ligases. The signalosome is involved in many regulatory process, including some which control development, in many species; also regulates photomorphogenesis in plants; in many species its subunits are highly similar to those of the proteasome.
48 O35864 (/IDA) O94454 (/IDA) Q5BBF1 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA)
(38 more)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
43 Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS)
(33 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
43 Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA)
(33 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
43 Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS)
(33 more)
Eukaryotic translation initiation factor 3 complex GO:0005852
A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs.
43 Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS) Q92905 (/TAS)
(33 more)
Synaptic vesicle GO:0008021
A secretory organelle, typically 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
43 Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA)
(33 more)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
43 Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA) Q92905 (/IDA)
(33 more)
COP9 signalosome GO:0008180
A protein complex that catalyzes the deneddylation of proteins, including the cullin component of SCF ubiquitin E3 ligase; deneddylation increases the activity of cullin family ubiquitin ligases. The signalosome is involved in many regulatory process, including some which control development, in many species; also regulates photomorphogenesis in plants; in many species its subunits are highly similar to those of the proteasome.
5 P91001 (/ISS) Q54PF3 (/ISS) Q5ZLC3 (/ISS) Q9XZ58 (/ISS) Q9XZ58 (/ISS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 O35864 (/ISS) Q6GLM9 (/ISS) Q6P635 (/ISS) Q6PC30 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 Q6GLM9 (/ISS) Q6P635 (/ISS) Q6PC30 (/ISS)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 A7TX80 (/IDA) F2Z540 (/IDA)
COP9 signalosome GO:0008180
A protein complex that catalyzes the deneddylation of proteins, including the cullin component of SCF ubiquitin E3 ligase; deneddylation increases the activity of cullin family ubiquitin ligases. The signalosome is involved in many regulatory process, including some which control development, in many species; also regulates photomorphogenesis in plants; in many species its subunits are highly similar to those of the proteasome.
2 Q9XZ58 (/NAS) Q9XZ58 (/NAS)
COP9 signalosome GO:0008180
A protein complex that catalyzes the deneddylation of proteins, including the cullin component of SCF ubiquitin E3 ligase; deneddylation increases the activity of cullin family ubiquitin ligases. The signalosome is involved in many regulatory process, including some which control development, in many species; also regulates photomorphogenesis in plants; in many species its subunits are highly similar to those of the proteasome.
2 Q9XZ58 (/TAS) Q9XZ58 (/TAS)
Nuclear periphery GO:0034399
The portion of the nuclear lumen proximal to the inner nuclear membrane.
2 Q9XZ58 (/IDA) Q9XZ58 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 O94454 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 O35864 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 O35864 (/ISO)
Transcription factor complex GO:0005667
A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
1 O35864 (/TAS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 O35864 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 O35864 (/ISS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 O94454 (/HDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 O35864 (/ISO)
Synaptic vesicle GO:0008021
A secretory organelle, typically 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
1 O35864 (/ISO)
COP9 signalosome GO:0008180
A protein complex that catalyzes the deneddylation of proteins, including the cullin component of SCF ubiquitin E3 ligase; deneddylation increases the activity of cullin family ubiquitin ligases. The signalosome is involved in many regulatory process, including some which control development, in many species; also regulates photomorphogenesis in plants; in many species its subunits are highly similar to those of the proteasome.
1 Q54PF3 (/IPI)
COP9 signalosome GO:0008180
A protein complex that catalyzes the deneddylation of proteins, including the cullin component of SCF ubiquitin E3 ligase; deneddylation increases the activity of cullin family ubiquitin ligases. The signalosome is involved in many regulatory process, including some which control development, in many species; also regulates photomorphogenesis in plants; in many species its subunits are highly similar to those of the proteasome.
1 O35864 (/ISO)
A band GO:0031672
The dark-staining region of a sarcomere, in which myosin thick filaments are present; the center is traversed by the paler H zone, which in turn contains the M line.
1 P91001 (/IDA)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
1 O35864 (/ISO)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
1 O35864 (/ISS)
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