The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Phosphorylase Kinase; domain 1
".
FunFam 732: Mitogen-activated protein kinase kinase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
MAP kinase kinase activity GO:0004708
Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate.
|
4 | Q9FX43 (/TAS) Q9FX43 (/TAS) Q9LPQ3 (/TAS) Q9LPQ3 (/TAS) |
|
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
|
2 | Q9FX43 (/IDA) Q9FX43 (/IDA) |
|
MAP kinase kinase activity GO:0004708
Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate.
|
2 | Q9FX43 (/IDA) Q9FX43 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | Q9FX43 (/IPI) Q9FX43 (/IPI) |
|
Kinase activity GO:0016301
Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
|
2 | Q9LPQ3 (/IDA) Q9LPQ3 (/IDA) |
|
Protein kinase activator activity GO:0030295
Binds to and increases the activity of a protein kinase, an enzyme which phosphorylates a protein.
|
2 | Q9FX43 (/IDA) Q9FX43 (/IDA) |
There are 13 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Defense response to oomycetes GO:0002229
Reactions triggered in response to the presence of oomycetes that act to protect the cell or organism.
|
2 | Q9LPQ3 (/IMP) Q9LPQ3 (/IMP) |
|
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
|
2 | Q9FX43 (/IEP) Q9FX43 (/IEP) |
|
Response to fungus GO:0009620
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a fungus.
|
2 | Q9FX43 (/IEP) Q9FX43 (/IEP) |
|
Response to salt stress GO:0009651
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
|
2 | Q9FX43 (/IMP) Q9FX43 (/IMP) |
|
Ethylene biosynthetic process GO:0009693
The chemical reactions and pathways resulting in the formation of ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator.
|
2 | Q9FX43 (/IDA) Q9FX43 (/IDA) |
|
Systemic acquired resistance, salicylic acid mediated signaling pathway GO:0009862
The series of molecular signals mediated by salicylic acid involved in systemic acquired resistance.
|
2 | Q9LPQ3 (/IMP) Q9LPQ3 (/IMP) |
|
Ethylene-activated signaling pathway GO:0009873
A series of molecular signals generated by the reception of ethylene (ethene, C2H4) by a receptor and ending with modulation of a cellular process, e.g. transcription.
|
2 | Q9FX43 (/IMP) Q9FX43 (/IMP) |
|
Auxin polar transport GO:0009926
The unidirectional movement of auxin in the stem from tip to base along the vector of gravity or basipetally.
|
2 | Q9LPQ3 (/IMP) Q9LPQ3 (/IMP) |
|
Camalexin biosynthetic process GO:0010120
The chemical reactions and pathways resulting in the formation of camalexin, an indole phytoalexin.
|
2 | Q9FX43 (/IDA) Q9FX43 (/IDA) |
|
Leaf senescence GO:0010150
The process that occurs in a leaf near the end of its active life that is associated with the dismantling of cell components and membranes, loss of functional chloroplasts, and an overall decline in metabolism.
|
2 | Q9FX43 (/IMP) Q9FX43 (/IMP) |
|
Defense response to bacterium GO:0042742
Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
|
2 | Q9LPQ3 (/IMP) Q9LPQ3 (/IMP) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | Q9FX43 (/IEP) Q9FX43 (/IEP) |
|
Protein autophosphorylation GO:0046777
The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).
|
2 | Q9FX43 (/IDA) Q9FX43 (/IDA) |
There are 0 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
