The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Phosphorylase Kinase; domain 1
".
FunFam 31: Non-specific serine/threonine protein kinase
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 47 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
55 |
A0A0B8RZS0 (/IPI)
A0A0B8RZS0 (/IPI)
B0LPE5 (/IPI)
B0LPE5 (/IPI)
B0LPE5 (/IPI)
B0LPE5 (/IPI)
B0LPE5 (/IPI)
B0LPE5 (/IPI)
B0LPE5 (/IPI)
G9BWQ2 (/IPI)
(45 more) |
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
|
42 |
P31749 (/IDA)
P31749 (/IDA)
P31749 (/IDA)
P31749 (/IDA)
P31749 (/IDA)
P31749 (/IDA)
P31749 (/IDA)
P31750 (/IDA)
P31751 (/IDA)
P47196 (/IDA)
(32 more) |
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
|
37 |
P31749 (/IDA)
P31749 (/IDA)
P31749 (/IDA)
P31749 (/IDA)
P31749 (/IDA)
P31749 (/IDA)
P31749 (/IDA)
P31751 (/IDA)
P47196 (/IDA)
P47197 (/IDA)
(27 more) |
Protein kinase activity GO:0004672
Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
|
33 |
P31749 (/TAS)
P31749 (/TAS)
P31749 (/TAS)
P31749 (/TAS)
P31749 (/TAS)
P31749 (/TAS)
P31749 (/TAS)
Q9Y243 (/TAS)
Q9Y243 (/TAS)
Q9Y243 (/TAS)
(23 more) |
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
|
12 |
P31749 (/TAS)
P31749 (/TAS)
P31749 (/TAS)
P31749 (/TAS)
P31749 (/TAS)
P31749 (/TAS)
P31749 (/TAS)
P31750 (/TAS)
P31751 (/TAS)
P47196 (/TAS)
(2 more) |
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
|
9 | P31749 (/EXP) P31749 (/EXP) P31749 (/EXP) P31749 (/EXP) P31749 (/EXP) P31749 (/EXP) P31749 (/EXP) Q60823 (/EXP) Q60823 (/EXP) |
Calmodulin binding GO:0005516
Interacting selectively and non-covalently with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.
|
8 | P31749 (/IDA) P31749 (/IDA) P31749 (/IDA) P31749 (/IDA) P31749 (/IDA) P31749 (/IDA) P31749 (/IDA) Q17941 (/IDA) |
Phosphatidylinositol-3,4,5-trisphosphate binding GO:0005547
Interacting selectively and non-covalently with phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions.
|
8 | P31749 (/IDA) P31749 (/IDA) P31749 (/IDA) P31749 (/IDA) P31749 (/IDA) P31749 (/IDA) P31749 (/IDA) Q17941 (/IDA) |
Protein serine/threonine kinase activity GO:0004674
Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
|
7 | P31749 (/NAS) P31749 (/NAS) P31749 (/NAS) P31749 (/NAS) P31749 (/NAS) P31749 (/NAS) P31749 (/NAS) |
Protein serine/threonine/tyrosine kinase activity GO:0004712
Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; ATP + a protein threonine = ADP + protein threonine phosphate; and ATP + a protein tyrosine = ADP + protein tyrosine phosphate.
|
7 | P31749 (/IDA) P31749 (/IDA) P31749 (/IDA) P31749 (/IDA) P31749 (/IDA) P31749 (/IDA) P31749 (/IDA) |
Showing 1 to 10 of 47 entries
There are 364 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Response to growth hormone GO:0060416
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth.
|
114 |
B0LPE5 (/ISS)
B0LPE5 (/ISS)
B0LPE5 (/ISS)
B0LPE5 (/ISS)
B0LPE5 (/ISS)
B0LPE5 (/ISS)
B0LPE5 (/ISS)
B3KVH4 (/ISS)
C1PIG3 (/ISS)
C5IJA6 (/ISS)
(104 more) |
Response to insulin-like growth factor stimulus GO:1990418
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin-like growth factor stimulus.
|
114 |
B0LPE5 (/ISS)
B0LPE5 (/ISS)
B0LPE5 (/ISS)
B0LPE5 (/ISS)
B0LPE5 (/ISS)
B0LPE5 (/ISS)
B0LPE5 (/ISS)
B3KVH4 (/ISS)
C1PIG3 (/ISS)
C5IJA6 (/ISS)
(104 more) |
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
|
34 |
P31749 (/TAS)
P31749 (/TAS)
P31749 (/TAS)
P31749 (/TAS)
P31749 (/TAS)
P31749 (/TAS)
P31749 (/TAS)
P31751 (/TAS)
Q9Y243 (/TAS)
Q9Y243 (/TAS)
(24 more) |
Positive regulation of endothelial cell proliferation GO:0001938
Any process that activates or increases the rate or extent of endothelial cell proliferation.
|
33 |
P31749 (/IMP)
P31749 (/IMP)
P31749 (/IMP)
P31749 (/IMP)
P31749 (/IMP)
P31749 (/IMP)
P31749 (/IMP)
Q9Y243 (/IMP)
Q9Y243 (/IMP)
Q9Y243 (/IMP)
(23 more) |
Positive regulation of blood vessel endothelial cell migration GO:0043536
Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels.
|
33 |
P31749 (/IDA)
P31749 (/IDA)
P31749 (/IDA)
P31749 (/IDA)
P31749 (/IDA)
P31749 (/IDA)
P31749 (/IDA)
Q9Y243 (/IDA)
Q9Y243 (/IDA)
Q9Y243 (/IDA)
(23 more) |
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
|
27 |
P47197 (/TAS)
Q9Y243 (/TAS)
Q9Y243 (/TAS)
Q9Y243 (/TAS)
Q9Y243 (/TAS)
Q9Y243 (/TAS)
Q9Y243 (/TAS)
Q9Y243 (/TAS)
Q9Y243 (/TAS)
Q9Y243 (/TAS)
(17 more) |
Mitochondrial genome maintenance GO:0000002
The maintenance of the structure and integrity of the mitochondrial genome; includes replication and segregation of the mitochondrial chromosome.
|
26 |
Q9Y243 (/IMP)
Q9Y243 (/IMP)
Q9Y243 (/IMP)
Q9Y243 (/IMP)
Q9Y243 (/IMP)
Q9Y243 (/IMP)
Q9Y243 (/IMP)
Q9Y243 (/IMP)
Q9Y243 (/IMP)
Q9Y243 (/IMP)
(16 more) |
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
|
26 |
Q9Y243 (/IMP)
Q9Y243 (/IMP)
Q9Y243 (/IMP)
Q9Y243 (/IMP)
Q9Y243 (/IMP)
Q9Y243 (/IMP)
Q9Y243 (/IMP)
Q9Y243 (/IMP)
Q9Y243 (/IMP)
Q9Y243 (/IMP)
(16 more) |
Positive regulation of cell migration involved in sprouting angiogenesis GO:0090050
Any process that increases the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis.
|
26 |
Q9Y243 (/IMP)
Q9Y243 (/IMP)
Q9Y243 (/IMP)
Q9Y243 (/IMP)
Q9Y243 (/IMP)
Q9Y243 (/IMP)
Q9Y243 (/IMP)
Q9Y243 (/IMP)
Q9Y243 (/IMP)
Q9Y243 (/IMP)
(16 more) |
Positive regulation of vascular endothelial cell proliferation GO:1905564
Any process that activates or increases the frequency, rate or extent of vascular endothelial cell proliferation.
|
26 |
Q9Y243 (/IDA)
Q9Y243 (/IDA)
Q9Y243 (/IDA)
Q9Y243 (/IDA)
Q9Y243 (/IDA)
Q9Y243 (/IDA)
Q9Y243 (/IDA)
Q9Y243 (/IDA)
Q9Y243 (/IDA)
Q9Y243 (/IDA)
(16 more) |
Showing 1 to 10 of 364 entries
There are 43 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
37 |
E1B9D1 (/IDA)
F1MYJ4 (/IDA)
F1MYJ4 (/IDA)
F1MYJ4 (/IDA)
F1MYJ4 (/IDA)
F1MYJ4 (/IDA)
F1MYJ4 (/IDA)
F1MYJ4 (/IDA)
F1MYJ4 (/IDA)
F1MYJ4 (/IDA)
(27 more) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
22 |
B0LPE5 (/IDA)
B0LPE5 (/IDA)
B0LPE5 (/IDA)
B0LPE5 (/IDA)
B0LPE5 (/IDA)
B0LPE5 (/IDA)
B0LPE5 (/IDA)
C1PIG3 (/IDA)
G9BWQ1 (/IDA)
M0R0P9 (/IDA)
(12 more) |
Microtubule cytoskeleton GO:0015630
The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.
|
14 |
B0LPE5 (/IDA)
B0LPE5 (/IDA)
B0LPE5 (/IDA)
B0LPE5 (/IDA)
B0LPE5 (/IDA)
B0LPE5 (/IDA)
B0LPE5 (/IDA)
P31749 (/IDA)
P31749 (/IDA)
P31749 (/IDA)
(4 more) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
13 |
P31749 (/TAS)
P31749 (/TAS)
P31749 (/TAS)
P31749 (/TAS)
P31749 (/TAS)
P31749 (/TAS)
P31749 (/TAS)
P31750 (/TAS)
P31751 (/TAS)
P47196 (/TAS)
(3 more) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
12 |
M0R0P9 (/IDA)
P31749 (/IDA)
P31749 (/IDA)
P31749 (/IDA)
P31749 (/IDA)
P31749 (/IDA)
P31749 (/IDA)
P31749 (/IDA)
P31751 (/IDA)
P47196 (/IDA)
(2 more) |
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
12 |
P31749 (/TAS)
P31749 (/TAS)
P31749 (/TAS)
P31749 (/TAS)
P31749 (/TAS)
P31749 (/TAS)
P31749 (/TAS)
P31750 (/TAS)
P31751 (/TAS)
Q60823 (/TAS)
(2 more) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
11 |
P31749 (/TAS)
P31749 (/TAS)
P31749 (/TAS)
P31749 (/TAS)
P31749 (/TAS)
P31749 (/TAS)
P31749 (/TAS)
P31751 (/TAS)
P47196 (/TAS)
P47197 (/TAS)
(1 more) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
11 |
C1PIG3 (/IDA)
G9BWQ1 (/IDA)
P31749 (/IDA)
P31749 (/IDA)
P31749 (/IDA)
P31749 (/IDA)
P31749 (/IDA)
P31749 (/IDA)
P31749 (/IDA)
P31750 (/IDA)
(1 more) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
9 | P31749 (/ISS) P31749 (/ISS) P31749 (/ISS) P31749 (/ISS) P31749 (/ISS) P31749 (/ISS) P31749 (/ISS) Q01314 (/ISS) Q98TY9 (/ISS) |
Protein-containing complex GO:0032991
A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
|
9 | P31749 (/IDA) P31749 (/IDA) P31749 (/IDA) P31749 (/IDA) P31749 (/IDA) P31749 (/IDA) P31749 (/IDA) P31750 (/IDA) P31751 (/IDA) |
Showing 1 to 10 of 43 entries