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CATH Superfamily 3.20.20.60

Phosphoenolpyruvate-binding domains

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Phosphoenolpyruvate-binding domains
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
Pyruvate kinase
2483
3D
 3khdD02 - 94.3
2
Pyruvate kinase
1197
3D
 6gg6H02 - 86.9
3
3-methyl-2-oxobutanoate hydroxymethyltransferase
728
3D
 1m3uJ00 - 95.7
4
5-keto-4-deoxy-D-glucarate aldolase
556
3D
 1dxfB00 - 93.0
5
Isocitrate lyase
486
3D
 1igwD00 - 86.0
6
Isocitrate lyase
442
3D
 1dquA01 - 87.0
7
Phosphoenolpyruvate-protein phosphotransferase
427
3D
 2xdfB02 - 84.3
8
Citrate
Pro-3S
304 - - 91.1
9
2-methylisocitrate lyase
291
3D
 1xg4D00 - 93.5
10
Phosphoenolpyruvate synthase
219
3D
 2olsA04 - 64.6
11
Pyruvate kinase
213 - - 70.5
12
Phosphoenolpyruvate-protein phosphotransferase PtsP
168 - - 67.4
13
Citrate lyase beta subunit
165 - - 88.5
14
Citrate lyase subunit beta-like protein
119 - - 93.8
15
Oxaloacetate decarboxylase
89
3D
 3b8iF00 - 30.4
18
Methylisocitrate lyase
68
3D
 4iqeB00 - 26.9
16
Isocitrate lyase
67 - - 55.4
17
3-methyl-2-oxobutanoate hydroxymethyltransferase
64 - - 47.8
20
Malyl-CoA lyase
59
3D
 4l9zF00 - 43.3
19
CoA ester lyase
57 - - 29.0
21
CoA ester lyase
41 - - 1.1
22
CoA ester lyase
41 - - 0.0
23
CitE, Citrate lyase beta subunit
40 - - 81.1
24
Isocitrate lyase
37 - - 30.3
25
Pyruvate kinase
34 - - 94.5
26
Pyruvate kinase
33 - - 30.1
28
2-keto-3-deoxy-L-rhamnonate aldolase-like
30 - - 68.8
27
Pyruvate kinase 2
30 - - 20.9
40
Pyruvate, phosphate dikinase, chloroplastic
25
3D
 2x0sA06 - 59.7
30
3-methyl-2-oxobutanoate hydroxymethyltransferase
24 - - 2.6
29
Unplaced genomic scaffold supercont1.2, whole genome shotgun sequence
24 - - 56.2
32
3-methyl-2-oxobutanoate hydroxymethyltransferase
23 - - 8.5
31
HpcH/HpaI aldolase
23 - - 35.0
33
CoA ester lyase
21 - - 26.6
38
Citrate lyase subunit beta-like protein
20
3D
 1z6kA00 - 14.2
34
Pyruvate kinase 2
20 - - 12.6
35
Pyruvate kinase
19 - - 13.6
36
ATP/GTP-binding protein
19 - - 36.1
37
3-methyl-2-oxobutanoate hydroxymethyltransferase
17 - - 15.9
39
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase
16 - - 43.9
44
HPCH/HPAI aldolase family protein
16
3D
 4tv6A00 - 7.8
41
3-methyl-2-oxobutanoate hydroxymethyltransferase
15 - - 8.8
42
Pyruvate kinase
15 - - 62.8
86
Malyl-CoA/beta-methylmalyl-CoA/citramalyl-CoA lyase
15
3D
 4l80F00 - 5.8
43
3-methyl-2-oxobutanoate hydroxymethyltransferase
14 - - 0.0
47
3-methyl-2-oxobutanoate hydroxymethyltransferase
13 - - 65.7
46
Pyruvate kinase
13 - - 35.3
45
Pyruvate kinase
13 - - 11.9
48
Pyruvate kinase
12 - - 22.8
49
HpcH/HpaI aldolase/citrate lyase family protein
11 - - 2.9
50
Citrate lyase beta subunit
11 - - 20.8
52
3-methyl-2-oxobutanoate hydroxymethyltransferase
10 - - 33.0
51
Pyruvate kinase family protein
10 - - 75.0
53
3-methyl-2-oxobutanoate hydroxymethyltransferase
9 - - 23.1
55
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative
9 - - 6.0
56
Macrophomate synthase, putative
9 - - 17.8
54
3-methyl-2-oxobutanoate hydroxymethyltransferase
9 - - 0.0
58
Isocitrate lyase
8 - - 7.5
57
Pyruvate kinase family protein
8 - - 63.8
63
Pyruvate kinase
7 - - 4.5
62
Pyruvate kinase
7 - - 8.0
61
Phosphoenolpyruvate carboxylase family protein
7 - - 6.9
60
Citrate lyase beta chain
7 - - 16.1
59
Acyl-CoA lyase subunit beta
7 - - 1.2
64
Pyruvate kinase
7 - - 49.9
65
Pyruvate kinase
6 - - 1.9
66
Pyruvate kinase
6 - - 4.5
100
Malate synthase
6
3D
 5taoA01 - 8.8
67
GG21066
6 - - 72.7
73
HpcH/HpaI aldolase/citrate lyase family, putative
5 - - 11.5
71
Citryl-CoA lyase
5 - - 6.5
72
3-methyl-2-oxobutanoate hydroxymethyltransferase
5 - - 10.1
75
Putative citrate lyase
5 - - 13.1
69
Pyruvate kinase
5 - - 64.8
70
Phosphotransferase system fructose-specific transporter subunit EI/HPr/EIIA
5 - - 0.0
68
Pyruvate kinase
5 - - 5.4
74
4-hydroxy-2-oxovalerate aldolase
5 - - 7.2
80
Pyruvate kinase
4 - - 13.4
76
HpcH/HpaI aldolase/citrate lyase family protein
4 - - 3.7
79
Putative aldolase
4 - - 5.1
152
Phosphonopyruvate hydrolase
4
3D
 2hrwA00 - 0.0
140
Citrate lyase subunit beta-like protein
4
3D
 1sgjC00 - 0.0
78
3-methyl-2-oxobutanoate hydroxymethyltransferase
4 - - 0.9
77
Citrate lyase subunit beta
4 - - 5.0
82
GD14986
4 - - 3.1
81
Pyruvate kinase
4 - - 11.5
89
Putative citrate/ citryl-CoA lyase
3 - - 10.0
88
Carboxyvinyl-carboxyphosphonate phosphorylmutase
3 - - 0.8
93
Pyruvate kinase
3 - - 79.9
92
Pyruvate kinase
3 - - 7.9
84
3-methyl-2-oxobutanoate hydroxymethyltransferase
3 - - 15.3
87
Isocitrate lyase AceAa
3 - - 0.0
91
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase
3 - - 2.1
90
GD12403
3 - - 13.6
83
N-Acetyl-D-Glucosamine phosphotransferase system transporter
3 - - 0.7
85
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase
3 - - 6.2
94
Predicted protein
3 - - 64.1
108
3-methyl-2-oxobutanoate hydroxymethyltransferase
2 - - 0.0
107
3-methyl-2-oxobutanoate hydroxymethyltransferase
2 - - 3.2
105
3-methyl-2-oxobutanoate hydroxymethyltransferase
2 - - 0.0
110
HpcH/HpaI aldolase
2 - - 0.0
109
HpcH/HpaI aldolase/citrate lyase family, putative
2 - - 0.0
104
Putative lysase
2 - - 0.0
95
Isocitrate lyase
2 - - 3.2
102
Uncharacterized protein
2 - - 25.2
111
Isocitrate lyase 1
2 - - 0.0
116
Pyruvate kinase
2 - - 0.5
96
Pyruvate kinase
2 - - 2.9
113
Oxaloacetate decarboxylase
2 - - 0.0
99
Pyruvate kinase
2 - - 0.0
114
Homolog to citrate lyase beta subunit
2 - - 1.8
112
Uncharacterized protein
2 - - 0.0
106
Uncharacterized protein
2 - - 0.0
101
Uncharacterized protein
2 - - 23.4
103
Uncharacterized protein
2 - - 44.2
118
3-methyl-2-oxobutanoate hydroxymethyltransferase 1 mitochondrial
2 - - 26.5
98
Pyruvate kinase
2 - - 0.0
117
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase
2 - - 0.0
115
Pyruvate kinase
2 - - 14.1
97
Isocitrate lyase
2 - - 1.5
149
Citrate lyase beta-like
1 - - 0.0
144
Predicted protein
1 - - 0.0
142
Uncharacterized protein
1 - - 0.0
148
Uncharacterized protein
1 - - 0.0
136
Isocitrate lyase
1 - - 0.0
131
Pyruvate kinase
1 - - 0.0
147
Uncharacterized protein
1 - - 0.0
150
Os01g0225400 protein
1 - - 0.0
120
Uncharacterized protein
1 - - 0.0
133
Predicted protein
1 - - 0.0
145
Pyruvate kinase
1 - - 0.0
130
Pyruvate kinase
1 - - 0.0
123
Malate synthase
1 - - 0.0
153
Uncharacterized protein
1 - - 0.0
121
Uncharacterized protein
1 - - 0.0
126
Uncharacterized protein
1 - - 0.0
151
Uncharacterized protein
1 - - 0.0
156
Aldolase like
1 - - 0.0
132
Uncharacterized protein
1 - - 0.0
124
Predicted protein
1 - - 0.0
154
Pyruvate kinase
1 - - 0.0
129
Uncharacterized protein
1 - - 0.0
119
Pyruvate kinase
1 - - 0.0
134
Pyruvate kinase
1 - - 0.0
139
3-methyl-2-oxobutanoate hydroxymethyltransferase
1 - - 0.0
122
Uncharacterized protein
1 - - 0.0
125
Isocitrate lyase
1 - - 0.0
155
Pyruvate kinase
1 - - 0.0
157
Aldolase like
1 - - 0.0
127
Pyruvate kinase
1 - - 0.0
128
Pyruvate kinase
1 - - 0.0
138
3-methyl-2-oxobutanoate hydroxymethyltransferase
1 - - 0.0
141
Predicted protein
1 - - 0.0
146
Aldolase like
1 - - 0.0
137
3-methyl-2-oxobutanoate hydroxymethyltransferase
1 - - 0.0
135
Pyruvate kinase
1 - - 0.0
143
Uncharacterized protein
1 - - 0.0
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