CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.20 | Alpha-Beta Barrel |
|
3.20.20 | TIM Barrel |
|
3.20.20.60 | Phosphoenolpyruvate-binding domains |
Domain Context
CATH Clusters
| Superfamily | Phosphoenolpyruvate-binding domains |
| Functional Family | Phosphoenolpyruvate-protein phosphotransferase |
Enzyme Information
| 2.7.3.9 |
Phosphoenolpyruvate--protein phosphotransferase.
based on mapping to UniProt P08839
Phosphoenolpyruvate + protein L-histidine = pyruvate + protein N(pi)- phospho-L-histidine.
-!- Acts only on histidine residues in specific phosphocarrier proteins of low molecular mass (9.5 kDa) involved in bacterial sugar transport. -!- A similar reaction where the protein is the enzyme EC 2.7.9.2 is part of the mechanism of that enzyme.
|
UniProtKB Entries (1)
| P0AA04 |
PTHP_ECOLI
Escherichia coli K-12
Phosphocarrier protein HPr
|
PDB Structure
| PDB | 2XDF |
| External Links | |
| Method | SOLUTION NMR |
| Organism | |
| Primary Citation |
Solution Structure of the 128 kDa Enzyme I Dimer from Escherichia Coli and its 146 kDa Complex with Hpr Using Residual Dipolar Couplings and Small- and Wide-Angle X-Ray Scattering.
J.Am.Chem.Soc.
|
