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CATH Superfamily 2.60.120.920

SPRY domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
SC:1neuralized-like protein 4 isoform X1ryanodine receptor isoform X2ryanodine receptor isoform X2Putative E3 ubiquitin-protein ligase NEURL1BSet1/Ash2 histone methyltransferase complex subunit ASH2RAN binding protein 10ATP-dependent RNA helicase DDX1LOW QUALITY PROTEIN: probable E3 ubiquitin-protein ligase HERC1SC:2Tripartite motif-containing 5 (Predicted)E3 ubiquitin-protein ligase TRIM50Ret finger protein-like 4AE3 ubiquitin/ISG15 ligase TRIM25Butyrophilin subfamily 1 member A1heterogeneous nuclear ribonucleoprotein U isoform X1SPRY domain-containing SOCS box protein 1E3 ubiquitin-protein ligase TRIM9 isoform X1E3 ubiquitin-protein ligase Midline-1Ryanodine receptor 2 (Cardiac)neuralized-like protein 4 isoform X2neuralized-like protein 4 isoform X2F-box/SPRY domain-containing protein 1SPRY domain-containing SOCS box protein 3 isoform X2Ryanodine receptor 1 (skeletal)Putative E3 ubiquitin-protein ligase NEURL1BSi:dkey-16p6.1E3 ubiquitin-protein ligase NEURL1 isoform X2Ryanodine receptor 3E3 ubiquitin-protein ligase TRIM41 isoform X1tripartite motif-containing protein 46 isoform X2Ryanodine receptor, isoform EE3 ubiquitin-protein ligase TRIM36probable E3 ubiquitin-protein ligase HECTD4 isoform X2E3 ubiquitin-protein ligase RNF123Tripartite motif-containing protein 26Si:dkeyp-100h4.1Fibronectin type III and SPRY domain-containing protein 1SplA/ryanodine receptor domain and SOCS box containing 1Tripartite motif-containing protein 35Si:dkey-191j3.2cardiomyopathy-associated protein 5Tripartite motif-containing protein 26E3 ubiquitin-protein ligase TRIM62neuralized-like protein 2 isoform X1Protein TRAUCOTripartite motif-containing protein 10tripartite motif-containing protein 16SPRY domain-containing protein 4SPRY domain-containing SOCS box protein 2Tripartite motif containing 4Neuralized E3 ubiquitin protein ligase 3Fibronectin type III and SPRY domain containing 2CBN-UNC-68 proteinE3 ubiquitin-protein ligase RKPHistone-lysine N-methyltransferase (Bre2), putativeUncharacterized proteinTripartite motif containing 14E3 ubiquitin-protein ligase TRIM17E3 ubiquitin-protein ligase TRIM69E3 ubiquitin-protein ligase RNF135Tripartite motif containing 39Tripartite motif containing 65Tripartite motif-containing protein 49Uncharacterized protein, isoform CAGAP009295-PA-like proteinEar1pSi:ch211-208f21.3ATP-dependent RNA helicase DDX1, putativeSPRY domainRyanodine receptor 44FNeuralized E3 ubiquitin protein ligase 2Compass component bre2Tripartite motif containing 38Butyrophilin like 3Neuralized protein 2Si:ch211-127b6.2ATP-dependent RNA helicase DDX1Tripartite motif containing 75, pseudogeneGD12021Predicted proteinUncharacterized proteinVacuolar import and degradation proteinCompass componentZn-finger in Ran binding protein and others/SPRY domain/HECT-domain (Ubiquitin-transferase), putativeSPRY_domain/HECT-domain_(Ubiquitin-transferase)_-_putativeSsh4pButyrophilin-like protein 1Tripartite motif-containing 5SPRY domain containing proteinDual specificity protein kinase splASi:ch211-214c20.1Uncharacterized proteinRan-binding protein M homologSi:dkey-103k4.1Uncharacterized proteinRyanodine receptor 1Si:dkey-31n13.4B-box and SPRY domain containingSPRY_domain/HECT-domain_(Ubiquitin-transferase)_-_putativeTripartite motif family-like 2Uncharacterized proteinNeuralized E3 ubiquitin protein ligase 1AbSi:ch211-201o1.1Predicted proteinE3 ubiquitin-protein ligase RNF123Protein CBG15934Ring finger protein 123Tripartite motif-containing protein 5Tripartite motif-containing protein 5Heterogeneous nuclear ribonucleoprotein U-like 2SPRY domain containing proteinProtein TRAUCOUncharacterized proteinUncharacterized proteinSi:ch211-76m11.5Si:ch211-207e19.2Uncharacterized proteinSi:ch73-236c18.7Predicted proteinSi:dkey-261j11.3Si:ch211-42i6.2Ryanodine receptor 3F-box/SPRY domain-containing protein 1Uncharacterized proteinNeuralized-like protein 4Zn-finger in Ran binding protein and others/SPRY domain/HECT-domain (Ubiquitin-transferase), putativeRyanodine receptor 3SPRY domain/Ankyrin repeats (3 copies), putativeNeuralized-like protein 4Uncharacterized proteinUncharacterized proteinNeuralized-like protein 2neuralized-like protein 2Uncharacterized proteinSPRY domain containing protein, putativeTRIM65 isoform 4E3 ubiquitin-protein ligase Midline-1Uncharacterized proteinTripartite motif containing 69 proteinFinTRIM family, member 82Uncharacterized proteinneuralized-a protein isoform X1Uncharacterized proteinProtein CBR-SPSB-2Cabz01076234.2Uncharacterized proteinButyrophilin subfamily 1 member A1Si:dkey-207m2.4Uncharacterized proteinUncharacterized proteinUncharacterized proteinSi:dkey-269o24.1Si:ch211-22k7.9Si:ch211-238e22.8Si:dkey-156k2.4Si:dkey-61p9.9Si:ch211-227e10.1Si:dkey-172k15.6Uncharacterized proteinUncharacterized proteinPredicted proteinProtein TRAUCOUncharacterized proteinPredicted proteinAsh2-like, histone lysine methyltransferase complex subunitUncharacterized proteinHNRNPUL2-BSCL2 readthrough (NMD candidate)Uncharacterized proteinMediterranean feverUncharacterized proteinUncharacterized proteinPredicted proteinUncharacterized proteinRyanodine receptor 2Uncharacterized proteinUncharacterized proteinUncharacterized proteinSi:dkeyp-4f2.1Uncharacterized proteinSi:dkeyp-123a12.2Uncharacterized proteinUncharacterized proteinPredicted proteinTrithorax protein ash2, putativeTripartite motif-containing protein 16Uncharacterized proteinNeuralized, putativeLOC100127740 proteinSi:dkey-23n7.10Uncharacterized proteinButyrophilin-like 7Predicted proteinBloodthirsty-related gene family, member 1Uncharacterized proteinUncharacterized proteinUncharacterized proteinLOC567531 proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinSi:dkey-56m15.9Si:ch211-227p7.5Uncharacterized proteinE3 ubiquitin-protein ligase NEURL1B-like proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinRyanodine receptor 1
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FunFam 40: Ret finger protein-like 4A

GO Diversity

Unique GO annotations
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16 Unique GO terms

EC Diversity

Unique EC annotations
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1 Unique EC terms

Species Diversity

Unique species annotations
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29 Unique species

Statistics

Members
CATH Domains: 4
Sequences: 64
Annotations
Unique GO: 16
Unique EC: 1
Unique Species: 29
Representative
Rep ID: 2fbeD00
Inherited Annotations: 0
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