CATH Superfamily 2.60.120.920

Browse Functional Families

ID	Function Family (FunFam) Name	Total Sequences	Structure?	Structural Representative	PDB Sites?	Alignment Diversity (0-100)
1	neuralized-like protein 4 isoform X1	978	3D	2e63A00	-	94.3
2	ryanodine receptor isoform X2	836	3D	5c33B00	-	87.0
3	ryanodine receptor isoform X2	763	3D	5vsnA00	-	93.0
4	Butyrophilin subfamily 1 member A1	646	3D	2iwgE00	-	93.5
5	Putative E3 ubiquitin-protein ligase NEURL1B	553	3D	4kg0A01	-	92.4
6	heterogeneous nuclear ribonucleoprotein U isoform X1	482		-	-	93.6
7	SPRY domain-containing SOCS box protein 1	368		-	-	74.7
8	Set1/Ash2 histone methyltransferase complex subunit ASH2	280	3D	5f6lB00	-	84.6
9	E3 ubiquitin-protein ligase TRIM9 isoform X1	268		-	-	75.9
11	RAN binding protein 10	263	3D	5jiuB00	-	72.4
10	E3 ubiquitin-protein ligase Midline-1	256		-	-	54.2
12	Ryanodine receptor 2 Cardiac	230		-	-	69.5
13	ATP-dependent RNA helicase DDX1	216	3D	4xw3B00	-	78.7
14	neuralized-like protein 4 isoform X2	211		-	-	74.7
15	LOW QUALITY PROTEIN: probable E3 ubiquitin-protein ligase HERC1	209	3D	4qt6A00	-	82.0
16	neuralized-like protein 4 isoform X2	200		-	-	72.9
17	F-box/SPRY domain-containing protein 1	193		-	-	71.7
18	SPRY domain-containing SOCS box protein 3 isoform X2	192		-	-	72.5
19	Ryanodine receptor 1 skeletal	168		-	-	87.7
20	Putative E3 ubiquitin-protein ligase NEURL1B	168		-	-	82.5
21	Si:dkey-16p6.1	167		-	-	79.5
22	E3 ubiquitin-protein ligase NEURL1 isoform X2	159		-	-	84.1
23	Tripartite motif-containing 5 Predicted	150	3D	4b3nB02	-	84.5
24	Ryanodine receptor 3	140		-	-	49.8
25	E3 ubiquitin-protein ligase TRIM41 isoform X1	135		-	-	82.3
26	tripartite motif-containing protein 46 isoform X2	124		-	-	21.9
27	E3 ubiquitin-protein ligase TRIM50	122	3D	3kb5A00	-	87.6
28	Ryanodine receptor, isoform E	119		-	-	35.9
29	E3 ubiquitin-protein ligase TRIM36	114		-	-	38.3
31	E3 ubiquitin-protein ligase RNF123	106		-	-	62.3
30	probable E3 ubiquitin-protein ligase HECTD4 isoform X2	106		-	-	28.6
32	Tripartite motif-containing protein 26	86		-	-	39.5
33	Si:dkeyp-100h4.1	78		-	-	72.9
34	Fibronectin type III and SPRY domain-containing protein 1	76		-	-	40.3
35	SplA/ryanodine receptor domain and SOCS box containing 1	75		-	-	78.2
36	Tripartite motif-containing protein 35	68		-	-	43.8
40	Ret finger protein-like 4A	68	3D	2fbeD00	-	95.5
37	Si:dkey-191j3.2	67		-	-	96.9
38	cardiomyopathy-associated protein 5	66		-	-	47.1
39	Tripartite motif-containing protein 26	65		-	-	38.9
45	E3 ubiquitin/ISG15 ligase TRIM25	61	3D	6flmC00	-	82.0
41	E3 ubiquitin-protein ligase TRIM62	61		-	-	15.3
42	neuralized-like protein 2 isoform X1	60		-	-	62.5
43	Protein TRAUCO	58		-	-	92.2
44	Tripartite motif-containing protein 10	57		-	-	88.8
46	tripartite motif-containing protein 16	55		-	-	44.8
48	SPRY domain-containing SOCS box protein 2	50		-	-	85.4
47	SPRY domain-containing protein 4	50		-	-	41.6
49	Tripartite motif containing 4	37		-	-	12.4
50	Neuralized E3 ubiquitin protein ligase 3	35		-	-	78.4
51	Fibronectin type III and SPRY domain containing 2	35		-	-	45.5
52	CBN-UNC-68 protein	33		-	-	31.5
53	E3 ubiquitin-protein ligase RKP	31		-	-	74.0
54	Histone-lysine N-methyltransferase Bre2	31		-	-	73.1
55	Uncharacterized protein	29		-	-	79.8
56	Tripartite motif containing 14	28		-	-	36.7
58	E3 ubiquitin-protein ligase TRIM69	24		-	-	62.0
60	Tripartite motif containing 39	24		-	-	46.4
57	E3 ubiquitin-protein ligase TRIM17	24		-	-	40.3
59	E3 ubiquitin-protein ligase RNF135	24		-	-	81.9
61	Tripartite motif containing 65	23		-	-	64.6
62	Tripartite motif-containing protein 49	22		-	-	32.5
63	Uncharacterized protein, isoform C	21		-	-	19.4
65	Ear1p	19		-	-	66.0
64	AGAP009295-PA-like protein	19		-	-	50.8
66	Si:ch211-208f21.3	18		-	-	80.4
67	ATP-dependent RNA helicase DDX1, putative	17		-	-	8.0
68	SPRY domain	17		-	-	4.5
71	Compass component bre2	16		-	-	86.2
69	Ryanodine receptor 44F	16		-	-	41.2
70	Neuralized E3 ubiquitin protein ligase 2	16		-	-	72.5
72	Tripartite motif containing 38	16		-	-	66.1
76	ATP-dependent RNA helicase DDX1	15		-	-	84.9
75	Si:ch211-127b6.2	15		-	-	42.7
74	Neuralized protein 2	15		-	-	78.1
73	Butyrophilin like 3	15		-	-	85.1
77	Tripartite motif containing 75, pseudogene	14		-	-	20.7
78	GD12021	13		-	-	70.6
80	Uncharacterized protein	12		-	-	83.7
79	Predicted protein	12		-	-	79.7
82	Compass component	11		-	-	85.8
81	Vacuolar import and degradation protein	11		-	-	9.5
83	Zn-finger in Ran binding protein and others/SPRY domain/HECT-domain Ubiquitin-transferase	10		-	-	42.4
85	Ssh4p	10		-	-	0.8
84	SPRY_domain/HECT-domain_ Ubiquitin-transferase	10		-	-	14.3
86	Butyrophilin-like protein 1	9		-	-	78.7
87	Tripartite motif-containing 5	8		-	-	53.4
90	Si:ch211-214c20.1	7		-	-	50.4
88	SPRY domain containing protein	7		-	-	8.3
89	Dual specificity protein kinase splA	7		-	-	84.2
92	Ran-binding protein M homolog	6		-	-	49.3
91	Uncharacterized protein	6		-	-	9.8
93	Si:dkey-103k4.1	5		-	-	21.1
94	Uncharacterized protein	5		-	-	11.3
99	Tripartite motif family-like 2	4		-	-	3.3
97	B-box and SPRY domain containing	4		-	-	12.5
101	Neuralized E3 ubiquitin protein ligase 1Ab	4		-	-	0.8
98	SPRY_domain/HECT-domain_ Ubiquitin-transferase	4		-	-	5.3
100	Uncharacterized protein	4		-	-	0.0
104	E3 ubiquitin-protein ligase RNF123	4		-	-	36.0
96	Si:dkey-31n13.4	4		-	-	37.9
103	Predicted protein	4		-	-	64.6
102	Si:ch211-201o1.1	4		-	-	72.5
95	Ryanodine receptor 1	4		-	-	19.7
110	SPRY domain containing protein	3		-	-	66.2
116	Uncharacterized protein	3		-	-	43.4
108	Tripartite motif-containing protein 5	3		-	-	35.0
114	Si:ch211-76m11.5	3		-	-	29.3
113	Uncharacterized protein	3		-	-	68.3
112	Uncharacterized protein	3		-	-	1.1
109	Heterogeneous nuclear ribonucleoprotein U-like 2	3		-	-	0.0
115	Si:ch211-207e19.2	3		-	-	24.3
107	Tripartite motif-containing protein 5	3		-	-	26.9
106	Ring finger protein 123	3		-	-	7.2
111	Protein TRAUCO	3		-	-	0.0
105	Protein CBG15934	3		-	-	12.2
131	Neuralized-like protein 2	2		-	-	0.0
142	Uncharacterized protein	2		-	-	6.1
145	Uncharacterized protein	2		-	-	37.5
137	Uncharacterized protein	2		-	-	0.0
128	Neuralized-like protein 4	2		-	-	0.0
139	FinTRIM family, member 82	2		-	-	0.6
138	Tripartite motif containing 69 protein	2		-	-	0.0
129	Uncharacterized protein	2		-	-	38.0
127	SPRY domain/Ankyrin repeats 3 copies	2		-	-	0.0
144	Cabz01076234.2	2		-	-	16.0
143	Protein CBR-SPSB-2	2		-	-	42.6
121	Ryanodine receptor 3	2		-	-	0.0
140	Uncharacterized protein	2		-	-	31.6
146	Butyrophilin subfamily 1 member A1	2		-	-	39.8
123	Uncharacterized protein	2		-	-	11.3
124	Neuralized-like protein 4	2		-	-	1.4
118	Predicted protein	2		-	-	42.9
147	Si:dkey-207m2.4	2		-	-	26.7
135	TRIM65 isoform 4	2		-	-	0.0
126	Ryanodine receptor 3	2		-	-	0.0
120	Si:ch211-42i6.2	2		-	-	0.0
132	neuralized-like protein 2	2		-	-	0.0
141	neuralized-a protein isoform X1	2		-	-	0.0
136	E3 ubiquitin-protein ligase Midline-1	2		-	-	4.4
125	Zn-finger in Ran binding protein and others/SPRY domain/HECT-domain Ubiquitin-transferase	2		-	-	0.0
122	F-box/SPRY domain-containing protein 1	2		-	-	2.4
130	Uncharacterized protein	2		-	-	47.8
133	Uncharacterized protein	2		-	-	7.0
117	Si:ch73-236c18.7	2		-	-	47.1
119	Si:dkey-261j11.3	2		-	-	11.3
134	SPRY domain containing protein, putative	2		-	-	0.0
201	Uncharacterized protein	1		-	-	0.0
155	Si:dkey-61p9.9	1		-	-	0.0
164	Ash2-like, histone lysine methyltransferase complex subunit	1		-	-	0.0
187	LOC100127740 protein	1		-	-	0.0
163	Predicted protein	1		-	-	0.0
152	Si:ch211-22k7.9	1		-	-	0.0
189	Uncharacterized protein	1		-	-	0.0
215	Ryanodine receptor 1	1		-	-	0.0
178	Uncharacterized protein	1		-	-	0.0
209	Uncharacterized protein	1		-	-	0.0
198	Uncharacterized protein	1		-	-	0.0
207	E3 ubiquitin-protein ligase NEURL1B-like protein	1		-	-	0.0
160	Predicted protein	1		-	-	0.0
166	HNRNPUL2-BSCL2 readthrough NMD candidate	1		-	-	0.0
181	Uncharacterized protein	1		-	-	0.0
212	Uncharacterized protein	1		-	-	0.0
177	Si:dkeyp-4f2.1	1		-	-	0.0
153	Si:ch211-238e22.8	1		-	-	0.0
199	Uncharacterized protein	1		-	-	0.0
162	Uncharacterized protein	1		-	-	0.0
197	Uncharacterized protein	1		-	-	0.0
208	Uncharacterized protein	1		-	-	0.0
179	Si:dkeyp-123a12.2	1		-	-	0.0
165	Uncharacterized protein	1		-	-	0.0
154	Si:dkey-156k2.4	1		-	-	0.0
210	Uncharacterized protein	1		-	-	0.0
213	Uncharacterized protein	1		-	-	0.0
156	Si:ch211-227e10.1	1		-	-	0.0
191	Predicted protein	1		-	-	0.0
171	Predicted protein	1		-	-	0.0
188	Si:dkey-23n7.10	1		-	-	0.0
150	Uncharacterized protein	1		-	-	0.0
214	Uncharacterized protein	1		-	-	0.0
173	Ryanodine receptor 2	1		-	-	0.0
157	Si:dkey-172k15.6	1		-	-	0.0
193	Uncharacterized protein	1		-	-	0.0
159	Uncharacterized protein	1		-	-	0.0
182	Predicted protein	1		-	-	0.0
211	Uncharacterized protein	1		-	-	0.0
185	Uncharacterized protein	1		-	-	0.0
194	Uncharacterized protein	1		-	-	0.0
149	Uncharacterized protein	1		-	-	0.0
174	Uncharacterized protein	1		-	-	0.0
176	Uncharacterized protein	1		-	-	0.0
205	Si:ch211-227p7.5	1		-	-	0.0
151	Si:dkey-269o24.1	1		-	-	0.0
196	LOC567531 protein	1		-	-	0.0
190	Butyrophilin-like 7	1		-	-	0.0
202	Uncharacterized protein	1		-	-	0.0
168	Mediterranean fever	1		-	-	0.0
170	Uncharacterized protein	1		-	-	0.0
175	Uncharacterized protein	1		-	-	0.0
195	Uncharacterized protein	1		-	-	0.0
206	Uncharacterized protein	1		-	-	0.0
184	Tripartite motif-containing protein 16	1		-	-	0.0
183	Trithorax protein ash2, putative	1		-	-	0.0
192	Bloodthirsty-related gene family, member 1	1		-	-	0.0
200	Uncharacterized protein	1		-	-	0.0
167	Uncharacterized protein	1		-	-	0.0
169	Uncharacterized protein	1		-	-	0.0
172	Uncharacterized protein	1		-	-	0.0
158	Uncharacterized protein	1		-	-	0.0
203	Uncharacterized protein	1		-	-	0.0
180	Uncharacterized protein	1		-	-	0.0
186	Neuralized, putative	1		-	-	0.0
204	Si:dkey-56m15.9	1		-	-	0.0
148	Uncharacterized protein	1		-	-	0.0
161	Protein TRAUCO	1		-	-	0.0

Network disruptions

Functional Families

Browse Functional Families