×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

View in Gene3D

CATH Superfamily 2.60.120.650

Cupin

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Cupin
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Browse Functional Families

ID Function Family (FunFam) Name Total Sequences Enzyme? Structure? Structural Representative PDB Sites? Alignment Diversity (0-100)
1
Putative lysine-specific demethylase 5b
983
3D
 6dqbA00 - 69.6
3
Lysine-specific demethylase 4D
971
3D
 5kr7B01 - 82.8
2
lysine-specific demethylase 6A isoform X2
745
3D
 6g8fA02 - 78.4
4
Putative lysine-specific demethylase 3B
449
3D
 4c8dA00 - 81.1
5
lysine-specific demethylase 2A isoform X1
300
3D
 4tn7C01 - 80.8
6
histone lysine demethylase PHF8 isoform X1
223
3D
 3kv4A01 - 48.9
7
Jumonji, AT rich interactive domain 2
214 - - 64.3
9
Putative lysine-specific demethylase 6B
205
3D
 4ezhB01 - 74.2
8
Probable JmjC domain-containing histone demethylation protein 2C
193
3D
 5fzoB01 - 78.8
10
bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 isoform X2
192
3D
 3ldbA01 - 70.4
11
PHD finger protein 2
177
3D
 3pusB01 - 56.4
48
Lysine-specific demethylase 4A
176
3D
 6h8pB01 - 64.7
12
Cupin superfamily protein family
160
3D
 4nubA01 - 33.6
13
Ribosomal oxygenase 1
158
3D
 4y4rB01 - 88.8
14
PHD transcription factor
Rum1
110 - - 71.1
19
Bifunctional peptidase and arginyl-hydroxylase JMJD5
104
3D
 6f4tA00 - 78.0
15
putative lysine-specific demethylase JMJ16
102
3D
 4igqA00 - 68.1
16
Lysine-specific demethylase isoform A
97 - - 71.0
17
lysine-specific demethylase hairless isoform X1
94 - - 59.2
18
HSPB1-associated protein 1 homolog
84 - - 87.1
22
tRNA wybutosine-synthesizing protein 5
83
3D
 3al6D01 - 77.2
21
Lysine-specific demethylase 7A
82
3D
 3u78A01 - 43.9
20
Lysine
K
80 - - 26.9
23
Probable lysine-specific demethylase ELF6
74 - - 75.3
24
Putative jumonji family transcription factor
72 - - 73.0
25
Lysine-specific demethylase 8
63 - - 94.5
26
Transcription factor jumonji domain-containing protein
61 - - 78.2
27
Jumonji/arid domain-containing protein
53 - - 82.0
28
Lysine-specific demethylase lid
44 - - 44.2
29
lysine-specific demethylase JMJ30
40 - - 76.2
30
JmjC domain-containing protein 4
36 - - 81.9
31
lysine-specific demethylase 5C isoform X10
34 - - 11.2
32
Ribosomal oxygenase 2
34
3D
 4bxfB01 - 34.6
33
Transcription factor jumonji
JmjC
31 - - 75.3
34
Transcription factor jumonji
JmjC
30 - - 70.0
35
PHD transcription factor Rum1
29 - - 89.7
38
Transcriptional repressor
29
3D
 3opwA01 - 81.6
36
Lysine-specific demethylase rbr-2
29 - - 75.9
37
Transcription factor jumonji
JmjC
27 - - 47.3
39
JmjC domain-containing protein 8
26 - - 40.8
40
lysine-specific demethylase JMJ25 isoform X1
25 - - 81.1
41
lysine-specific demethylase 5C isoform X6
23 - - 29.0
42
Transcription factor jumonji
JmjC
21 - - 69.1
43
tRNA wybutosine-synthesizing protein 4
20 - - 90.2
44
Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 21
19 - - 25.1
45
F-box protein At1g78280
17 - - 82.3
47
Putative jumonji family transcription factor
16 - - 71.6
46
JmjC domain-containing protein D
16 - - 82.7
50
Putative jumonji-like transcription factor family protein
14 - - 43.0
49
JmjC domain protein, putative
14 - - 75.2
51
JmjC domain containing protein
13 - - 2.6
137
Lysine-specific demethylase 7 homolog
13
3D
 3purC02 - 1.2
52
Predicted protein
12 - - 77.2
53
2-oxoglutarate
2OG II
11 - - 71.9
55
Jhd2p
10 - - 58.9
54
Histone H3-K36 demethylase
10 - - 2.7
57
Cupin-like domain-containing protein
9 - - 90.8
56
Jumonji domain containing 5
9 - - 83.3
61
Glucosamine 6-phosphate N-acetyltransferase
9 - - 85.1
59
Ecm5p
9 - - 6.5
60
Histone demethylase JHD2
9 - - 3.9
58
Lysine-specific demethylase JMJ25 isoform A
9 - - 30.3
62
Probable inactive lysine-specific demethylase JMJ19
8 - - 83.4
66
lysine-specific demethylase 8-like
7 - - 85.4
63
JmjC domain containing protein
7 - - 8.5
64
Lysine-specific demethylase jmjd-3.1
7 - - 86.2
65
Uncharacterized protein
7 - - 8.5
68
UTX
Ubiquitously transcribed TPR on X
6 - - 70.1
69
Lysine demethylase 5A
6 - - 10.0
70
40S ribosomal protein S4-3
6 - - 31.5
67
Uncharacterized protein, isoform A
6 - - 15.5
78
Predicted protein
5 - - 41.3
73
Cupin_superfamily_protein/Cupin-like_domain_containing_protein_-_putative
5 - - 42.9
72
Lysine-specific demethylase 3
5 - - 19.0
76
Lysine-specific demethylase 6A isoform 1
5 - - 0.0
77
Multicopy suppressor of chk1 protein 1
5 - - 73.6
74
JmjC domain containing protein
5 - - 2.1
75
Uncharacterized protein B13D15.230
5 - - 3.4
71
Lysine
K
5 - - 58.9
86
CXXC finger protein 1
4 - - 65.4
79
Uncharacterized protein
4 - - 21.4
82
Uncharacterized protein
4 - - 71.2
89
Lysine-specific demethylase 4
4 - - 22.6
88
Predicted protein
4 - - 57.1
92
Specific transcriptional repressor
4 - - 38.4
83
Protein CBG17151
4 - - 69.2
81
Predicted protein
4 - - 60.5
84
Uncharacterized protein
4 - - 31.2
85
Uncharacterized protein
4 - - 73.0
91
Chromosome 10, whole genome shotgun sequence
4 - - 81.6
87
Uncharacterized protein
4 - - 8.9
80
JmjC domain-containing protein A
4 - - 68.2
90
Mitochondrial carrier protein
4 - - 67.0
111
Jumonji/ARID domain-containing protein 2
3 - - 34.8
96
Uncharacterized protein
3 - - 32.4
103
JmjC domain containing protein
3 - - 1.4
100
JuMonJi
Transcription factor
3 - - 67.8
109
Lysine-specific demethylase rbr-2
3 - - 67.7
98
Jumonji domain-containing protein, putative
3 - - 47.9
107
ARID/BRIGHT DNA binding domain-containing protein
3 - - 41.4
101
Uncharacterized protein
3 - - 38.2
93
Uncharacterized protein AT4g21430
3 - - 10.2
99
Jumonji, AT-rich interactive domain 2a
3 - - 34.3
110
Predicted protein
3 - - 38.0
94
Protein associating with small stress protein PASS1
3 - - 7.6
105
JmjC domain-containing histone demethylase, putative
3 - - 8.1
102
Histone lysine demethylase PHF8
3 - - 2.6
95
RIOX2 isoform 6
3 - - 0.0
104
Lysine-specific demethylase 4B
3 - - 19.4
106
Transcription factor jumonji
JmjC
3 - - 0.0
97
Unplaced genomic scaffold supercont2.18, whole genome shotgun sequence
3 - - 10.3
108
Uncharacterized protein
3 - - 52.1
117
Uncharacterized protein
2 - - 21.6
119
Uncharacterized protein
2 - - 35.8
134
Predicted protein
2 - - 35.6
122
GM16352
2 - - 9.2
136
AaceriAFL127Cp
2 - - 10.1
125
AGAP004022-PA
2 - - 4.6
141
Uncharacterized protein
2 - - 0.0
132
Uncharacterized protein
2 - - 0.0
135
Predicted protein
2 - - 15.8
126
C-module-binding factor A
2 - - 6.9
124
YALI0F28105p
2 - - 0.0
147
Uncharacterized protein
2 - - 38.9
149
Uncharacterized protein
2 - - 37.0
150
Uncharacterized protein
2 - - 41.2
140
tRNA wybutosine-synthesizing protein 5
2 - - 0.9
143
Uncharacterized protein
2 - - 0.0
138
YALI0C16390p
2 - - 0.0
113
JmjC domain containing protein, expressed
2 - - 27.2
128
Uncharacterized protein
2 - - 10.9
148
Uncharacterized protein
2 - - 10.8
133
Uncharacterized protein
2 - - 24.4
130
Uncharacterized protein
2 - - 0.0
120
Uncharacterized protein
2 - - 20.7
118
Uncharacterized protein
2 - - 33.4
123
Lysine-specific demethylase 8
2 - - 0.0
146
Uncharacterized protein
2 - - 40.9
115
Predicted protein
2 - - 32.0
121
Lysine-specific demethylase JMJ25
2 - - 0.0
112
Uncharacterized protein
2 - - 13.6
129
lysine-specific demethylase 3B
2 - - 0.0
127
Predicted protein
2 - - 1.0
144
Uncharacterized protein
2 - - 33.6
139
Protein Jumonji
2 - - 0.4
114
Os02g0109501 protein
2 - - 29.5
116
Jmjd2b-prov protein
2 - - 29.4
145
Uncharacterized protein
2 - - 34.8
142
YALI0B14443p
2 - - 0.0
131
Uncharacterized protein
2 - - 0.0
235
Predicted protein
1 - - 0.0
186
Uncharacterized protein
1 - - 0.0
226
Predicted protein
1 - - 0.0
203
Uncharacterized protein
1 - - 0.0
241
Lysine
K
1 - - 0.0
232
Lid2 complex component lid2
1 - - 0.0
200
Uncharacterized protein
1 - - 0.0
192
Uncharacterized protein
1 - - 0.0
224
Bifunctional arginine demethylase and lysyl-hydroxylase psr-1
1 - - 0.0
195
Uncharacterized protein
1 - - 0.0
184
Putative lysine-specific demethylase ELF6
1 - - 0.0
168
Uncharacterized protein
1 - - 0.0
170
HR, lysine demethylase and nuclear receptor corepressor
1 - - 0.0
217
Uncharacterized protein
1 - - 0.0
151
Uncharacterized protein
1 - - 0.0
234
Histone lysine demethylase PHF8
1 - - 0.0
219
Predicted protein
1 - - 0.0
196
Uncharacterized protein
1 - - 0.0
185
Uncharacterized protein
1 - - 0.0
194
Putative lysine-specific demethylase ELF6
1 - - 0.0
236
Predicted protein
1 - - 0.0
225
40S ribosomal protein S4-3
1 - - 0.0
173
Uncharacterized protein
1 - - 0.0
222
Multicopy suppressor of chk1 protein 1
1 - - 0.0
157
Predicted protein
1 - - 0.0
159
Uncharacterized protein
1 - - 0.0
182
Uncharacterized protein
1 - - 0.0
211
Predicted protein
1 - - 0.0
188
Uncharacterized protein
1 - - 0.0
228
Predicted protein
1 - - 0.0
213
Uncharacterized protein
1 - - 0.0
171
Lysine demethylase 4C
1 - - 0.0
165
Uncharacterized protein
1 - - 0.0
210
Uncharacterized protein
1 - - 0.0
177
Predicted protein
1 - - 0.0
153
Predicted protein
1 - - 0.0
162
Uncharacterized protein
1 - - 0.0
179
Uncharacterized protein
1 - - 0.0
166
Uncharacterized protein
1 - - 0.0
240
Uncharacterized protein
1 - - 0.0
209
Uncharacterized protein
1 - - 0.0
198
Uncharacterized protein
1 - - 0.0
207
Uncharacterized protein
1 - - 0.0
238
Uncharacterized protein
1 - - 0.0
243
Uncharacterized protein
1 - - 0.0
201
Uncharacterized protein
1 - - 0.0
164
Predicted protein
1 - - 0.0
204
Putative lysine-specific demethylase JMJ16
1 - - 0.0
161
Uncharacterized protein
1 - - 0.0
220
Uncharacterized protein
1 - - 0.0
158
Predicted protein
1 - - 0.0
180
Uncharacterized protein
1 - - 0.0
183
Os12g0169500 protein
1 - - 0.0
167
Os02g0109400 protein
1 - - 0.0
169
Lysine-specific demethylase REF6
1 - - 0.0
172
Uncharacterized protein
1 - - 0.0
223
Uncharacterized protein
1 - - 0.0
175
Uncharacterized protein
1 - - 0.0
218
HSPB1 associated protein 1
1 - - 0.0
206
Uncharacterized protein
1 - - 0.0
233
Uncharacterized protein
1 - - 0.0
190
Uncharacterized protein
1 - - 0.0
202
Uncharacterized protein
1 - - 0.0
176
PHD zinc finger-containing protein
1 - - 0.0
205
Predicted protein
1 - - 0.0
174
Uncharacterized protein
1 - - 0.0
193
Predicted protein
1 - - 0.0
230
Predicted protein
1 - - 0.0
237
Uncharacterized protein
1 - - 0.0
214
Uncharacterized protein
1 - - 0.0
239
40S ribosomal protein S4-3
1 - - 0.0
156
Uncharacterized protein
1 - - 0.0
191
Uncharacterized protein
1 - - 0.0
154
Lid2 complex component jmj3
1 - - 0.0
242
Uncharacterized protein
1 - - 0.0
231
Uncharacterized protein
1 - - 0.0
245
Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66
1 - - 0.0
199
Uncharacterized protein
1 - - 0.0
216
Uncharacterized protein
1 - - 0.0
197
Lysine demethylase 4C
1 - - 0.0
208
ABR167Cp
1 - - 0.0
221
Uncharacterized protein
1 - - 0.0
181
Predicted protein
1 - - 0.0
212
Putative lysine-specific demethylase JMJ16
1 - - 0.0
178
Uncharacterized protein
1 - - 0.0
215
Uncharacterized protein
1 - - 0.0
246
Predicted protein
1 - - 0.0
160
Uncharacterized protein
1 - - 0.0
229
Uncharacterized protein
1 - - 0.0
187
Uncharacterized protein
1 - - 0.0
163
Chromosome 7, whole genome shotgun sequence
1 - - 0.0
152
Uncharacterized protein
1 - - 0.0
244
Uncharacterized protein
1 - - 0.0
189
Uncharacterized protein
1 - - 0.0
227
Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66
1 - - 0.0
155
Uncharacterized protein
1 - - 0.0
CATH-Gene3D is a Global Biodata Core Resource Learn more...