The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 17: hepatoma-derived growth factor isoform X1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 28 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
26 Q923W4 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS)
(16 more)
Tubulin binding GO:0015631
Interacting selectively and non-covalently with monomeric or multimeric forms of tubulin, including microtubules.
26 Q923W4 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS)
(16 more)
Supercoiled DNA binding GO:0097100
Interacting selectively and non-covalently with supercoiled DNA. For example, during replication and transcription, template DNA is negatively supercoiled in the receding downstream DNA and positively supercoiled in the approaching downstream DNA.
11 A1YAF7 (/ISS) B8Y8S3 (/ISS) D2H2Y2 (/ISS) E2REJ7 (/ISS) O75475 (/ISS) O75475 (/ISS) O75475 (/ISS) Q5XXA9 (/ISS) Q66T72 (/ISS) Q8MJG1 (/ISS)
(1 more)
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
7 A1YAF7 (/ISS) B8Y8S3 (/ISS) D2H2Y2 (/ISS) E2REJ7 (/ISS) Q5XXA9 (/ISS) Q66T72 (/ISS) Q8MJG1 (/ISS)
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
7 A1YAF7 (/ISS) B8Y8S3 (/ISS) D2H2Y2 (/ISS) E2REJ7 (/ISS) Q5XXA9 (/ISS) Q66T72 (/ISS) Q8MJG1 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
7 O75475 (/IPI) O75475 (/IPI) O75475 (/IPI) P51859 (/IPI) Q3UMU9 (/IPI) Q7Z4V5 (/IPI) Q9JMG7 (/IPI)
Activating transcription factor binding GO:0033613
Interacting selectively and non-covalently with an activating transcription factor, any protein whose activity is required to initiate or upregulate transcription.
7 A1YAF7 (/ISS) B8Y8S3 (/ISS) D2H2Y2 (/ISS) E2REJ7 (/ISS) Q5XXA9 (/ISS) Q66T72 (/ISS) Q8MJG1 (/ISS)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
5 O75475 (/HDA) O75475 (/HDA) O75475 (/HDA) P51858 (/HDA) P51858 (/HDA)
Heparin binding GO:0008201
Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
3 P51859 (/ISS) Q8VHK7 (/ISS) Q9XSK7 (/ISS)
Transcription corepressor binding GO:0001222
Interacting selectively and non-covalently with a transcription corepressor, any protein involved in negative regulation of transcription via protein-protein interactions with transcription factors and other proteins that negatively regulate transcription. Transcription corepressors do not bind DNA directly, but rather mediate protein-protein interactions between repressing transcription factors and the basal transcription machinery.
2 P51858 (/IPI) P51858 (/IPI)
Transcription corepressor activity GO:0003714
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to repress the transcription of specific genes. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class occludes DNA-binding transcription factor protein-protein interaction domains. A fourth class of corepressors prevents interactions of DNA bound DNA-binding transcription factor with coactivators.
2 P51858 (/IDA) P51858 (/IDA)
Heparin binding GO:0008201
Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
2 P51858 (/TAS) P51858 (/TAS)
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
1 Q8VHK7 (/IDA)
RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a specific upstream regulatory DNA sequence (transcription factor recognition sequence or binding site) located in the proximal promoter of a gene transcribed by RNA polymerase II. The proximal promoter is in cis with and relatively close to the core promoter.
1 P51859 (/ISO)
Transcription corepressor binding GO:0001222
Interacting selectively and non-covalently with a transcription corepressor, any protein involved in negative regulation of transcription via protein-protein interactions with transcription factors and other proteins that negatively regulate transcription. Transcription corepressors do not bind DNA directly, but rather mediate protein-protein interactions between repressing transcription factors and the basal transcription machinery.
1 P51859 (/ISO)
DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to repress or decrease transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
1 Q8VHK7 (/IDA)
DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to repress or decrease transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
1 P51859 (/ISO)
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
1 Q99JF8 (/ISO)
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
1 Q9JMG7 (/NAS)
DNA-binding transcription factor activity GO:0003700
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
1 Q9XER9 (/ISS)
Transcription coactivator activity GO:0003713
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to activate the transcription of specific genes. Coactivators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. Another type of coregulator activity is the bridging of a DNA-binding transcription factor to the basal transcription machinery. The Mediator complex, which bridges transcription factors and RNA polymerase, is also a transcription coactivator.
1 Q99JF8 (/ISO)
Transcription corepressor activity GO:0003714
A protein or a member of a complex that interacts specifically and non-covalently with a DNA-bound DNA-binding transcription factor to repress the transcription of specific genes. Corepressors often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second ATP-dependent class modifies the conformation of chromatin. A third class occludes DNA-binding transcription factor protein-protein interaction domains. A fourth class of corepressors prevents interactions of DNA bound DNA-binding transcription factor with coactivators.
1 P51859 (/ISO)
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
1 Q9JMG7 (/IDA)
Growth factor activity GO:0008083
The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation.
1 P51859 (/ISO)
Tubulin binding GO:0015631
Interacting selectively and non-covalently with monomeric or multimeric forms of tubulin, including microtubules.
1 Q9JMG7 (/IDA)
Activating transcription factor binding GO:0033613
Interacting selectively and non-covalently with an activating transcription factor, any protein whose activity is required to initiate or upregulate transcription.
1 Q99JF8 (/ISO)
Supercoiled DNA binding GO:0097100
Interacting selectively and non-covalently with supercoiled DNA. For example, during replication and transcription, template DNA is negatively supercoiled in the receding downstream DNA and positively supercoiled in the approaching downstream DNA.
1 Q812D1 (/IDA)
Supercoiled DNA binding GO:0097100
Interacting selectively and non-covalently with supercoiled DNA. For example, during replication and transcription, template DNA is negatively supercoiled in the receding downstream DNA and positively supercoiled in the approaching downstream DNA.
1 Q99JF8 (/ISO)

There are 36 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Negative regulation of microtubule depolymerization GO:0007026
Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
26 Q923W4 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS)
(16 more)
Neuron projection development GO:0031175
The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
26 Q923W4 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS)
(16 more)
Microtubule polymerization GO:0046785
The addition of tubulin heterodimers to one or both ends of a microtubule.
26 Q923W4 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS)
(16 more)
Cell population proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
25 Q9Y3E1 (/NAS) Q9Y3E1 (/NAS) Q9Y3E1 (/NAS) Q9Y3E1 (/NAS) Q9Y3E1 (/NAS) Q9Y3E1 (/NAS) Q9Y3E1 (/NAS) Q9Y3E1 (/NAS) Q9Y3E1 (/NAS) Q9Y3E1 (/NAS)
(15 more)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
11 A1YAF7 (/ISS) B8Y8S3 (/ISS) D2H2Y2 (/ISS) E2REJ7 (/ISS) O75475 (/ISS) O75475 (/ISS) O75475 (/ISS) Q5XXA9 (/ISS) Q66T72 (/ISS) Q812D1 (/ISS)
(1 more)
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
11 A1YAF7 (/ISS) B8Y8S3 (/ISS) D2H2Y2 (/ISS) E2REJ7 (/ISS) O75475 (/ISS) O75475 (/ISS) O75475 (/ISS) Q5XXA9 (/ISS) Q66T72 (/ISS) Q812D1 (/ISS)
(1 more)
MRNA 5'-splice site recognition GO:0000395
Recognition of the intron 5'-splice site by components of the assembling spliceosome.
9 A1YAF7 (/ISS) B8Y8S3 (/ISS) D2H2Y2 (/ISS) E2REJ7 (/ISS) Q5XXA9 (/ISS) Q66T72 (/ISS) Q812D1 (/ISS) Q8MJG1 (/ISS) Q99JF8 (/ISS)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
7 A1YAF7 (/ISS) B8Y8S3 (/ISS) D2H2Y2 (/ISS) E2REJ7 (/ISS) Q5XXA9 (/ISS) Q66T72 (/ISS) Q8MJG1 (/ISS)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
3 P51858 (/IDA) P51858 (/IDA) Q8VHK7 (/IDA)
MRNA 5'-splice site recognition GO:0000395
Recognition of the intron 5'-splice site by components of the assembling spliceosome.
3 O75475 (/IDA) O75475 (/IDA) O75475 (/IDA)
Nuclear transport GO:0051169
The directed movement of substances into, out of, or within the nucleus.
3 O75475 (/TAS) O75475 (/TAS) O75475 (/TAS)
Positive regulation of cell division GO:0051781
Any process that activates or increases the frequency, rate or extent of cell division.
3 P51859 (/ISS) Q8VHK7 (/ISS) Q9XSK7 (/ISS)
Establishment of integrated proviral latency GO:0075713
A process by which the virus integrates into the host genome and establishes as a stable provirus or prophage.
3 O75475 (/TAS) O75475 (/TAS) O75475 (/TAS)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
2 P51858 (/NAS) P51858 (/NAS)
Positive regulation of cell growth GO:0030307
Any process that activates or increases the frequency, rate, extent or direction of cell growth.
2 Q3UMU9 (/ISS) Q925G1 (/ISS)
IRE1-mediated unfolded protein response GO:0036498
A series of molecular signals mediated by the endoplasmic reticulum stress sensor IRE1 (Inositol-requiring transmembrane kinase/endonuclease). Begins with activation of IRE1 in response to endoplasmic reticulum (ER) stress, and ends with regulation of a downstream cellular process, e.g. transcription. One target of activated IRE1 is the transcription factor HAC1 in yeast, or XBP1 in mammals; IRE1 cleaves an intron of a mRNA coding for HAC1/XBP1 to generate an activated HAC1/XBP1 transcription factor, which controls the up regulation of UPR-related genes. At least in mammals, IRE1 can also signal through additional intracellular pathways including JNK and NF-kappaB.
2 P51858 (/TAS) P51858 (/TAS)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
2 P51859 (/ISO) Q99JF8 (/ISO)
Negative regulation of transcription by RNA polymerase II GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription mediated by RNA polymerase II.
1 P51859 (/ISO)
MRNA 5'-splice site recognition GO:0000395
Recognition of the intron 5'-splice site by components of the assembling spliceosome.
1 Q99JF8 (/ISO)
MRNA processing GO:0006397
Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.
1 Q9XER9 (/IMP)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
1 Q99JF8 (/IDA)
Negative regulation of microtubule depolymerization GO:0007026
Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
1 Q9JMG7 (/IDA)
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
1 Q99JF8 (/IDA)
Negative regulation of flower development GO:0009910
Any process that stops, prevents, or reduces the frequency, rate or extent of flower development.
1 Q9XER9 (/IMP)
Cellular process GO:0009987
Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
1 P51859 (/IDA)
Positive regulation of cell growth GO:0030307
Any process that activates or increases the frequency, rate, extent or direction of cell growth.
1 Q7Z4V5 (/IMP)
Positive regulation of cell growth GO:0030307
Any process that activates or increases the frequency, rate, extent or direction of cell growth.
1 Q3UMU9 (/ISO)
Neuron projection development GO:0031175
The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
1 Q9JMG7 (/IMP)
Protein localization to nucleus GO:0034504
A process in which a protein transports or maintains the localization of another protein to the nucleus.
1 Q8VHK7 (/IDA)
Protein localization to nucleus GO:0034504
A process in which a protein transports or maintains the localization of another protein to the nucleus.
1 P51859 (/ISO)
Anthocyanin accumulation in tissues in response to UV light GO:0043481
The aggregation of the pigment anthocyanin in a particular location in a tissue, occurring in response to a UV light stimulus.
1 Q9XER9 (/IMP)
Positive regulation of transcription by RNA polymerase II GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 Q8VHK7 (/IDA)
Microtubule polymerization GO:0046785
The addition of tubulin heterodimers to one or both ends of a microtubule.
1 Q9JMG7 (/IDA)
Maintenance of floral organ identity GO:0048497
The process in which the identity of a floral organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
1 Q9XER9 (/IMP)
Regulation of timing of transition from vegetative to reproductive phase GO:0048510
The process controlling the point in time during development when a vegetative meristem will change its identity to become an inflorescence or floral meristem, and/or the rate at which the change occurs.
1 Q9XER9 (/IMP)
Cellular response to interleukin-7 GO:0098761
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-7 stimulus.
1 P51859 (/IDA)

There are 27 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
55 A0A024R216 (/IDA) A0A024R216 (/IDA) A0A024R216 (/IDA) A0A024R216 (/IDA) A0A024R216 (/IDA) A0A024R216 (/IDA) A0A024R216 (/IDA) A0A024R216 (/IDA) A0A024R216 (/IDA) A0A024R216 (/IDA)
(45 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
34 F4IN78 (/IDA) F4IZM8 (/IDA) P51859 (/IDA) Q3UMU9 (/IDA) Q5XXA9 (/IDA) Q8VHK7 (/IDA) Q9JMG7 (/IDA) Q9LEY4 (/IDA) Q9XER9 (/IDA) Q9Y3E1 (/IDA)
(24 more)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
27 P51858 (/HDA) P51858 (/HDA) Q9Y3E1 (/HDA) Q9Y3E1 (/HDA) Q9Y3E1 (/HDA) Q9Y3E1 (/HDA) Q9Y3E1 (/HDA) Q9Y3E1 (/HDA) Q9Y3E1 (/HDA) Q9Y3E1 (/HDA)
(17 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
26 Q923W4 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS) Q9Y3E1 (/ISS)
(16 more)
Transcriptionally active chromatin GO:0035327
The ordered and organized complex of DNA and protein that forms regions of the chromosome that are being actively transcribed.
11 A1YAF7 (/ISS) B8Y8S3 (/ISS) D2H2Y2 (/ISS) E2REJ7 (/ISS) O75475 (/ISS) O75475 (/ISS) O75475 (/ISS) Q5XXA9 (/ISS) Q66T72 (/ISS) Q8MJG1 (/ISS)
(1 more)
Nuclear heterochromatin GO:0005720
A condensed form of chromatin, occurring in the nucleus during interphase, that stains strongly with basophilic dyes. The DNA of heterochromatin is typically replicated at a later stage in the cell-division cycle than euchromatin.
8 A1YAF7 (/ISS) B8Y8S3 (/ISS) D2H2Y2 (/ISS) E2REJ7 (/ISS) Q5XXA9 (/ISS) Q66T72 (/ISS) Q8MJG1 (/ISS) Q99JF8 (/ISS)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
5 O75475 (/TAS) O75475 (/TAS) O75475 (/TAS) P51858 (/TAS) P51858 (/TAS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 P51859 (/ISO) Q99JF8 (/ISO) Q9JMG7 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
3 P51859 (/ISO) Q99JF8 (/ISO) Q9JMG7 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
3 O75475 (/TAS) O75475 (/TAS) O75475 (/TAS)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
2 P51858 (/HDA) P51858 (/HDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
2 Q8VHK7 (/ISS) Q9XSK7 (/ISS)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
2 P51858 (/TAS) P51858 (/TAS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q923W4 (/ISS) Q9JMG7 (/ISS)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 P51858 (/TAS) P51858 (/TAS)
Transcriptional repressor complex GO:0017053
A protein complex that possesses activity that prevents or downregulates transcription.
2 P51858 (/IDA) P51858 (/IDA)
Collagen-containing extracellular matrix GO:0062023
An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells.
2 P51858 (/HDA) P51858 (/HDA)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 P51859 (/IDA)
Nuclear heterochromatin GO:0005720
A condensed form of chromatin, occurring in the nucleus during interphase, that stains strongly with basophilic dyes. The DNA of heterochromatin is typically replicated at a later stage in the cell-division cycle than euchromatin.
1 Q812D1 (/IDA)
Nuclear heterochromatin GO:0005720
A condensed form of chromatin, occurring in the nucleus during interphase, that stains strongly with basophilic dyes. The DNA of heterochromatin is typically replicated at a later stage in the cell-division cycle than euchromatin.
1 Q99JF8 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9JMG7 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9JMG7 (/IDA)
Plasmodesma GO:0009506
A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
1 Q9LEY4 (/IDA)
Transcriptional repressor complex GO:0017053
A protein complex that possesses activity that prevents or downregulates transcription.
1 P51859 (/ISO)
Nuclear periphery GO:0034399
The portion of the nuclear lumen proximal to the inner nuclear membrane.
1 Q99JF8 (/ISO)
Transcriptionally active chromatin GO:0035327
The ordered and organized complex of DNA and protein that forms regions of the chromosome that are being actively transcribed.
1 Q812D1 (/IDA)
Transcriptionally active chromatin GO:0035327
The ordered and organized complex of DNA and protein that forms regions of the chromosome that are being actively transcribed.
1 Q99JF8 (/ISO)
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