The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Cystine-knot cytokines
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 67: Prothoracicotropic hormone, isoform F

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Prothoracicotrophic hormone activity GO:0018445
The action characteristic of prothoracicotrophic hormone, a peptide hormone that is secreted by the brain and, upon receptor binding, acts on the prothoracic gland to stimulate the release of ecdysone in insects.
3 A0A0S0WMK2 (/IDA) Q9VPR8 (/IDA) X2JCX9 (/IDA)

There are 6 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Metamorphosis GO:0007552
A biological process in which an animal physically develops after birth or hatching, involving a conspicuous and relatively abrupt change in the animal's form or structure. Examples include the change from tadpole to frog, and the change from larva to adult. An example of this is found in Drosophila melanogaster.
3 A0A0S0WMK2 (/IMP) Q9VPR8 (/IMP) X2JCX9 (/IMP)
Torso signaling pathway GO:0008293
A series of molecular signals initiated by the binding of an extracellular ligand to torso (a receptor tyrosine kinase) on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
3 A0A0S0WMK2 (/IMP) Q9VPR8 (/IMP) X2JCX9 (/IMP)
Regulation of endocrine process GO:0044060
Any process that modulates the frequency, rate or extent of an endocrine process, a process involving the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system.
3 A0A0S0WMK2 (/IMP) Q9VPR8 (/IMP) X2JCX9 (/IMP)
Positive regulation of ecdysteroid biosynthetic process GO:0045998
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ecdysteroids.
3 A0A0S0WMK2 (/IDA) Q9VPR8 (/IDA) X2JCX9 (/IDA)
Negative phototaxis GO:0046957
The directed movement of a cell or organism away from a source of light.
3 A0A0S0WMK2 (/IMP) Q9VPR8 (/IMP) X2JCX9 (/IMP)
Torso signaling pathway GO:0008293
A series of molecular signals initiated by the binding of an extracellular ligand to torso (a receptor tyrosine kinase) on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
1 X2JCX9 (/IDA)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Varicosity GO:0043196
Non-terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters.
3 A0A0S0WMK2 (/IDA) Q9VPR8 (/IDA) X2JCX9 (/IDA)
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