The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Cystine-knot cytokines
".
FunFam 45: DAN domain BMP antagonist family member 5
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q76LW6 (/IPI) |
|
Morphogen activity GO:0016015
Acts as a trigger for a pattern specification process when present at a specific concentration within a gradient.
|
1 | Q76LW6 (/IMP) |
|
Morphogen activity GO:0016015
Acts as a trigger for a pattern specification process when present at a specific concentration within a gradient.
|
1 | Q8N907 (/ISS) |
There are 21 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Determination of left/right asymmetry in lateral mesoderm GO:0003140
The establishment of the lateral mesoderm with respect to the left and right halves.
|
1 | Q76LW6 (/IMP) |
|
Determination of left/right asymmetry in lateral mesoderm GO:0003140
The establishment of the lateral mesoderm with respect to the left and right halves.
|
1 | Q8N907 (/ISS) |
|
Ventricular septum development GO:0003281
The progression of the ventricular septum over time from its formation to the mature structure.
|
1 | Q76LW6 (/IMP) |
|
Ventricular septum development GO:0003281
The progression of the ventricular septum over time from its formation to the mature structure.
|
1 | Q8N907 (/ISS) |
|
Atrial septum development GO:0003283
The progression of the atrial septum over time, from its initial formation to the mature structure.
|
1 | Q76LW6 (/IMP) |
|
Atrial septum development GO:0003283
The progression of the atrial septum over time, from its initial formation to the mature structure.
|
1 | Q8N907 (/ISS) |
|
Determination of left/right symmetry GO:0007368
The establishment of an organism's body plan or part of an organism with respect to the left and right halves. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry.
|
1 | Q76LW6 (/IGI) |
|
Determination of left/right symmetry GO:0007368
The establishment of an organism's body plan or part of an organism with respect to the left and right halves. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry.
|
1 | Q76LW6 (/IMP) |
|
Regulation of transforming growth factor beta receptor signaling pathway GO:0017015
Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway.
|
1 | Q76LW6 (/IDA) |
|
Negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512
Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway.
|
1 | Q76LW6 (/IGI) |
|
Negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512
Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway.
|
1 | Q8N907 (/ISS) |
|
Negative regulation of BMP signaling pathway GO:0030514
Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway.
|
1 | Q76LW6 (/IDA) |
|
Negative regulation of BMP signaling pathway GO:0030514
Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway.
|
1 | Q8N907 (/ISS) |
|
Sequestering of nodal from receptor via nodal binding GO:0038101
Binding to a nodal protein in the extracellular region, and inhibiting nodal signaling by preventing nodal from binding to its cell surface receptor.
|
1 | Q76LW6 (/IDA) |
|
Sequestering of nodal from receptor via nodal binding GO:0038101
Binding to a nodal protein in the extracellular region, and inhibiting nodal signaling by preventing nodal from binding to its cell surface receptor.
|
1 | Q8N907 (/ISS) |
|
Determination of heart left/right asymmetry GO:0061371
Determination of the asymmetric location of the heart with respect to the left and right halves of the organism.
|
1 | Q76LW6 (/IMP) |
|
Determination of heart left/right asymmetry GO:0061371
Determination of the asymmetric location of the heart with respect to the left and right halves of the organism.
|
1 | Q8N907 (/ISS) |
|
Negative regulation of nodal signaling pathway GO:1900108
Any process that stops, prevents or reduces the frequency, rate or extent of nodal signaling pathway.
|
1 | Q76LW6 (/IDA) |
|
Negative regulation of nodal signaling pathway GO:1900108
Any process that stops, prevents or reduces the frequency, rate or extent of nodal signaling pathway.
|
1 | Q8N907 (/ISS) |
|
Negative regulation of nodal signaling pathway involved in determination of left/right asymmetry GO:1900146
Any process that stops, prevents or reduces the frequency, rate or extent of a nodal signaling pathway, where the nodal signaling pathway is involved in determination of left/right asymmetry.
|
1 | Q76LW6 (/ISS) |
|
Nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry GO:1900164
A series of molecular signals initiated by the binding of a nodal protein to an activin receptor on the surface of a target cell, which contributes to the establishment of lateral mesoderm with respect to the left and right halves.
|
1 | Q76LW6 (/NAS) |
There are 1 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
2 | Q76LW6 (/NAS) Q8N907 (/NAS) |
