The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Cystine-knot cytokines
".
FunFam 33: Muellerian-inhibiting factor
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 6 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
1 | P03971 (/IPI) |
|
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
1 | P27106 (/ISO) |
|
Transforming growth factor beta receptor binding GO:0005160
Interacting selectively and non-covalently with the transforming growth factor beta receptor.
|
1 | P49000 (/IDA) |
|
Transforming growth factor beta receptor binding GO:0005160
Interacting selectively and non-covalently with the transforming growth factor beta receptor.
|
1 | P27106 (/ISO) |
|
Hormone activity GO:0005179
The action characteristic of a hormone, any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone, which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants, and to synthetic substances having comparable effects; all bind receptors and trigger some biological process.
|
1 | P03971 (/TAS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | P49000 (/IPI) |
There are 24 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Germ cell development GO:0007281
The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism.
|
3 | A8E7B8 (/IMP) Q50D78 (/IMP) Q6B6Q2 (/IMP) |
|
Sperm capacitation GO:0048240
A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium.
|
3 | A8E7B8 (/IMP) Q50D78 (/IMP) Q6B6Q2 (/IMP) |
|
Negative regulation of androgen secretion GO:2000835
Any process that stops, prevents or reduces the frequency, rate or extent of androgen secretion.
|
3 | A8E7B8 (/IDA) Q50D78 (/IDA) Q6B6Q2 (/IDA) |
|
Preantral ovarian follicle growth GO:0001546
Increase in size of follicles surrounded by two or more layers of granulosa cells up to the onset of antrum formation.
|
1 | P49000 (/IDA) |
|
Preantral ovarian follicle growth GO:0001546
Increase in size of follicles surrounded by two or more layers of granulosa cells up to the onset of antrum formation.
|
1 | P27106 (/ISO) |
|
Urogenital system development GO:0001655
The process whose specific outcome is the progression of the urogenital system over time, from its formation to the mature structure.
|
1 | P49000 (/IDA) |
|
Urogenital system development GO:0001655
The process whose specific outcome is the progression of the urogenital system over time, from its formation to the mature structure.
|
1 | P27106 (/ISO) |
|
Mullerian duct regression GO:0001880
The process in which the Mullerian ducts, primordia of the oviducts, uterus and upper vagina, undergo regression in male embryos.
|
1 | P03971 (/IDA) |
|
Mullerian duct regression GO:0001880
The process in which the Mullerian ducts, primordia of the oviducts, uterus and upper vagina, undergo regression in male embryos.
|
1 | P27106 (/ISO) |
|
Mullerian duct regression GO:0001880
The process in which the Mullerian ducts, primordia of the oviducts, uterus and upper vagina, undergo regression in male embryos.
|
1 | P03971 (/NAS) |
|
Mullerian duct regression GO:0001880
The process in which the Mullerian ducts, primordia of the oviducts, uterus and upper vagina, undergo regression in male embryos.
|
1 | P49000 (/TAS) |
|
Cell-cell signaling GO:0007267
Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions.
|
1 | P03971 (/TAS) |
|
Sex determination GO:0007530
Any process that establishes and transmits the specification of sexual status of an individual organism.
|
1 | P03971 (/TAS) |
|
Sex differentiation GO:0007548
The establishment of the sex of an organism by physical differentiation.
|
1 | P03971 (/TAS) |
|
Aging GO:0007568
A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).
|
1 | P49000 (/IEP) |
|
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
1 | P03971 (/IMP) |
|
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
1 | P27106 (/ISO) |
|
Response to organic cyclic compound GO:0014070
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
|
1 | P49000 (/IEP) |
|
BMP signaling pathway GO:0030509
A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | P03971 (/TAS) |
|
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
|
1 | P49000 (/IEP) |
|
Positive regulation of NF-kappaB transcription factor activity GO:0051092
Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB.
|
1 | P49000 (/IMP) |
|
Positive regulation of NF-kappaB transcription factor activity GO:0051092
Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB.
|
1 | P27106 (/ISO) |
|
Negative regulation of ovarian follicle development GO:2000355
Any process that stops, prevents or reduces the frequency, rate or extent of ovarian follicle development.
|
1 | P49000 (/IDA) |
|
Negative regulation of ovarian follicle development GO:2000355
Any process that stops, prevents or reduces the frequency, rate or extent of ovarian follicle development.
|
1 | P27106 (/ISO) |
There are 8 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Endoplasmic reticulum GO:0005783
The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
|
2 | E3UBG7 (/IDA) Q5XZF0 (/IDA) |
|
Cortical granule GO:0060473
A secretory vesicle that is stored under the cell membrane of an egg. These vesicles fuse with the egg plasma membrane as part of egg activation and are part of the block to polyspermy.
|
2 | E3UBG7 (/IDA) Q5XZF0 (/IDA) |
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
1 | P03971 (/NAS) |
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
1 | P03971 (/TAS) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
1 | P49000 (/IDA) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
1 | P27106 (/ISO) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
1 | P03971 (/TAS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | P27106 (/IDA) |
