The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:
"Cystine-knot cytokines
".
FunFam 23: Platelet-derived growth factor subunit B
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 27 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Growth factor activity GO:0008083
The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation.
|
7 | P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS) |
|
Superoxide-generating NADPH oxidase activator activity GO:0016176
Increases the activity of the enzyme superoxide-generating NADPH oxidase.
|
7 | P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
7 | P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS) |
|
Platelet-derived growth factor receptor binding GO:0005161
Interacting selectively and non-covalently with the platelet-derived growth factor receptor.
|
6 | P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS) |
|
Signaling receptor binding GO:0005102
Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
|
2 | P31240 (/ISO) P31240 (/ISO) |
|
Platelet-derived growth factor receptor binding GO:0005161
Interacting selectively and non-covalently with the platelet-derived growth factor receptor.
|
2 | P01127 (/IDA) P01127 (/IDA) |
|
Platelet-derived growth factor receptor binding GO:0005161
Interacting selectively and non-covalently with the platelet-derived growth factor receptor.
|
2 | P01127 (/IPI) P01127 (/IPI) |
|
Platelet-derived growth factor receptor binding GO:0005161
Interacting selectively and non-covalently with the platelet-derived growth factor receptor.
|
2 | P31240 (/ISO) P31240 (/ISO) |
|
Platelet-derived growth factor receptor binding GO:0005161
Interacting selectively and non-covalently with the platelet-derived growth factor receptor.
|
2 | P01127 (/NAS) P01127 (/NAS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | P01127 (/IPI) P01127 (/IPI) |
Showing 1 to 10 of 27 entries
There are 213 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cellular response to mycophenolic acid GO:0071506
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycophenolic acid stimulus.
|
8 | P01127 (/ISS) P01127 (/ISS) P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS) |
|
Embryonic placenta development GO:0001892
The embryonically driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.
|
7 | P01127 (/ISS) P01127 (/ISS) P12919 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS) |
|
Monocyte chemotaxis GO:0002548
The movement of a monocyte in response to an external stimulus.
|
7 | P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS) |
|
Positive regulation of glomerular filtration GO:0003104
Any process that activates or increases the frequency, rate or extent of glomerular filtration. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule.
|
7 | P01127 (/ISS) P01127 (/ISS) P12919 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS) |
|
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
|
7 | P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS) |
|
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
|
7 | P01127 (/ISS) P01127 (/ISS) P12919 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS) |
|
Positive regulation of cell population proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
|
7 | P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS) |
|
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
|
7 | P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS) |
|
Negative regulation of phosphatidylinositol biosynthetic process GO:0010512
Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol.
|
7 | P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS) |
|
Negative regulation of platelet activation GO:0010544
Any process that decreases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.
|
7 | P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS) |
Showing 1 to 10 of 213 entries
There are 22 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
8 | P01127 (/ISS) P01127 (/ISS) P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS) |
|
Basolateral plasma membrane GO:0016323
The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
|
8 | P01127 (/ISS) P01127 (/ISS) P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
7 | P12919 (/ISS) P31240 (/ISS) P31240 (/ISS) Q05028 (/ISS) Q6Q7I7 (/ISS) Q6Q7I7 (/ISS) Q95229 (/ISS) |
|
Golgi membrane GO:0000139
The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
|
2 | P01127 (/TAS) P01127 (/TAS) |
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
2 | P01127 (/NAS) P01127 (/NAS) |
|
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
|
2 | P01127 (/TAS) P01127 (/TAS) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
2 | P31240 (/ISO) P31240 (/ISO) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | P31240 (/ISO) P31240 (/ISO) |
|
Endoplasmic reticulum lumen GO:0005788
The volume enclosed by the membranes of the endoplasmic reticulum.
|
2 | P01127 (/TAS) P01127 (/TAS) |
|
Golgi lumen GO:0005796
The volume enclosed by the membranes of any cisterna or subcompartment of the Golgi apparatus, including the cis- and trans-Golgi networks.
|
2 | P01127 (/TAS) P01127 (/TAS) |
Showing 1 to 10 of 22 entries
