The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Neurotransmitter-gated ion-channel transmembrane domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
SC:1Cholinergic receptor nicotinic beta 1 subunitCholinergic receptor nicotinic alpha 1 subunitSC:2Gamma-aminobutyric acid receptor subunit beta-2 isoform ACholinergic receptor nicotinic beta 4 subunitGlutamate-gated chloride channel alphaProton-gated ion channelNeuronal nicotinic acetylcholine receptor subunit 3Putative gamma-aminobutyric acid receptor subunit alpha-5Glycine receptor alpha 2 subunitPutative gamma-aminobutyric acid receptor subunit rho-2-likePutative gamma-aminobutyric acid receptor subunit gamma-2Neuronal acetylcholine receptor subunit alpha-7Cholinergic receptor nicotinic alpha 9 subunitNicotinic acetylcholine receptor subunit epsilonneuronal acetylcholine receptor subunit alpha-7Acetylcholine receptor subunit alpha-likePutative acetylcholine receptor subunit alphaNeuronal nicotinic acetylcholine receptor alpha4 subunitGamma-aminobutyric acid (GABA-A) receptor, subunit deltaPutative acetylcholine receptor subunit alphaNeuronal acetylcholine receptor subunit alpha-3Glycine receptor subunit betaGamma-aminobutyric acid (GABA) A receptor, pi5-hydroxytryptamine (serotonin) receptor 3Aglutamate-gated chloride channel isoform X12Nicotinic acetylcholine receptor subunit alpha4Nicotinic acetylcholine receptor subunit alpha6Cholinergic receptor nicotinic beta 3 subunitCholinergic receptor nicotinic beta 1 subunitHistamine-gated chloride channel subunitCholinergic receptor nicotinic beta 2 subunitacetylcholine receptor subunit delta isoform X1Acetylcholine receptor subunit alpha-L1gamma-aminobutyric acid receptor subunit epsilonGamma-aminobutyric acid receptor subunit betaCholinergic receptor nicotinic beta 4 subunitAcetylcholine receptor subunit beta-like 1Nicotinic acetylcholine receptor subunit gammaNicotinic acetylcholine receptor subunit alpha6Acetylcholine receptor subunit beta-like 1Ligand-Gated ion ChannelGamma-aminobutyric acid receptor subunit beta-likeNeuronal acetylcholine receptor subunit alpha-55-hydroxytryptamine receptor 3CAcetylCholine Receptorneuronal acetylcholine receptor subunit alpha-9neuronal acetylcholine receptor subunit alpha-10AcetylCholine ReceptorResistance to dieldrin, isoform HCholinergic receptor nicotinic epsilon subunitAcetylCholine Receptorglycine receptor subunit alpha-4Cholinergic receptor, nicotinic, alpha 6Neuronal acetylcholine receptor subunit alpha-9Gamma-aminobutyric acid (GABA-A) receptor, subunit thetaLigand-Gated ion Channel5-hydroxytryptamine receptor 3BResistance to dieldrin, isoform ENicotinic acetylcholine receptor alpha6, isoform DNicotinic acetylcholine receptor alpha6, isoform DLigand-Gated ion ChannelLigand-Gated ion ChannelNeurotransmitter-gated ion-channel transmembrane regionAcetylCholine ReceptorNeuronal acetylcholine receptor subunit alpha-7GABA-gated ion channelAcetylcholine receptor subunit alpha-type unc-63Glycine receptor subunit alpha-2zinc-activated ligand-gated ion channelLigand-Gated ion ChannelGlycine receptor betaLigand-Gated ion ChannelUncharacterized proteinNeuronal acetylcholine receptor subunit alpha-9-IIGamma-aminobutyric acid type A receptor gamma2 subunitNeuronal acetylcholine receptor subunit alpha-9-IIGlutamate-gated chloride channel, putativeLigand-gated ion channel 50AcetylCholine ReceptorCholinergic receptor, nicotinic, epsilon5-hydroxytryptamine (serotonin) receptor 3C, ionotropicProton-gated ion channel subunit pbo-5Glutamate-gated ChLoride channelLigand-Gated ion ChannelGlutamate-gated chloride channel subunit betaGamma-aminobutyric acid type A receptor pi subunitAcetylcholine receptor subunit beta-type acr-2GABA-gated ion channelUncharacterized proteinLigand-Gated ion ChannelLigand-Gated ion ChannelGlycine receptor, beta aNicotinic acetylcholine receptor subunit alpha10Uncharacterized proteinLigand-Gated ion ChannelIonotropic GABA receptor subunit UNC-49B.3Ligand-Gated ion ChannelGamma-aminobutyric acid (GABA) A receptor, beta 2Predicted proteinCholinergic receptor, nicotinic, epsilonPredicted proteinUncharacterized proteinGlycine receptor subunit beta-type 4Si:ch211-256e16.10AcetylCholine ReceptorAcetylCholine ReceptorACHA7AcetylCholine ReceptorUncharacterized proteinAcetylCholine ReceptorUncharacterized proteinAcetylCholine ReceptorAcetylcholine receptor subunit alpha-type unc-63Ionotropic GABA receptor subunit UNC-49CshortUncharacterized proteinGABA/Glycine Receptor family (See gbr)Gamma-aminobutyric acid type A receptor beta2 subunitUncharacterized proteinGABA-gated ion channelAcetylCholine Receptor5-hydroxytryptamine receptor 3AUncharacterized proteinUncharacterized proteinUncharacterized proteinProtein CBG26995Acetylcholine-gated ion channel acc-4Ligand-Gated ion ChannelAcetylCholine ReceptorNeuronal acetylcholine receptor subunit eat-2AcetylCholine ReceptorSi:ch211-256e16.7Predicted proteinUncharacterized proteinLigand-Gated ion ChannelLigand-Gated ion ChannelLigand-Gated ion ChannelPredicted proteinPredicted proteinAcetylCholine ReceptorNeuronal acetylcholine receptor subunit eat-2Predicted proteinUncharacterized protein5-hydroxytryptamine receptor 3DProtein CBR-ACR-25Predicted proteinUncharacterized proteinUncharacterized proteinTransmembrane ion channelUncharacterized proteinNeurotransmitter-gated ion-channel ligand binding domain proteinAcetylCholine ReceptorGABA/Glycine Receptor family (See gbr)Acetylcholine receptor subunit alpha-type acr-7CBN-LEV-8 proteinNicotinic acetylcholine receptor subunitUncharacterized proteinIonotropic GABA receptor subunit UNC-49CNicotinic acetylcholine receptor subunitAcetylcholine receptor subunit alpha-type acr-165-hydroxytryptamine (serotonin) receptor 3BUncharacterized proteinUncharacterized proteinAcetylcholine receptor subunit alphaPredicted proteinAGAP007707-PAUncharacterized proteinNicotinic acetylcholine receptor subunitCholinergic receptor nicotinic beta 1 subunitUncharacterized proteinPredicted proteinGlycine receptor alpha 1 variant, putativeUncharacterized proteinPredicted proteinNicotinic acetylcholine receptor subunitPredicted proteinPredicted proteinUncharacterized proteinPredicted proteinPredicted proteinUncharacterized proteinPredicted proteinPredicted proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinGamma-aminobutyric acid (GABA) A receptor, alpha 3Ligand-Gated ion ChannelUncharacterized proteinPredicted proteinUncharacterized proteinPredicted proteinPredicted proteinPredicted proteinUncharacterized proteinGamma-aminobutyric acid type A receptor rho3 subunit (gene/pseudogene)Uncharacterized proteinGlutamate-gated chloride channel, putativeTransmembrane ion channelLigand-gated ion channelUncharacterized proteinGamma-aminobutyric acid type A receptor pi subunitTransmembrane ion channelPredicted proteinNeurotransmitter-gated ion-channel ligand binding domain proteinUncharacterized proteinUncharacterized proteinCholinergic receptor nicotinic delta subunitUncharacterized proteinCholinergic receptor nicotinic alpha 10 subunitNicotinic acetylcholine receptor subunitUncharacterized proteinNicotinic acetylcholine receptor subunitAcr-19Uncharacterized proteinNicotinic acetylcholine receptor subunitNicotinic acetylcholine receptor subunitUncharacterized proteinUncharacterized proteinGamma-aminobutyric acid (GABA) A receptor, alpha 1Uncharacterized proteinAcetylCholine ReceptorUncharacterized proteinPredicted proteinUncharacterized proteinPredicted proteinPredicted proteinGlycine receptor alpha chain, putativeUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinProtein CBR-LGC-39Uncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinGamma-aminobutyric acid type A receptor alpha6 subunitUncharacterized proteinUncharacterized proteinUncharacterized proteinAGAP009493-PAUncharacterized proteinUncharacterized proteinSi:ch211-256e16.4Uncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinGlycine receptor alpha 4Uncharacterized proteinUncharacterized proteinGlycine receptor alpha 1 variant, putativeGlutamate-gated chloride channel, putativeUncharacterized proteinUncharacterized proteinUncharacterized proteinPredicted proteinZinc activated ion channelUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinSD09326pUncharacterized proteinUncharacterized proteinPredicted proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinSi:dkey-49c17.4Uncharacterized proteinUncharacterized proteinGABA-A receptor epsilon subunitPredicted proteinUncharacterized proteinCholinergic receptor, nicotinic, alpha polypeptide 9Uncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinCholinergic receptor nicotinic gamma subunitUncharacterized proteinUncharacterized proteinHypothetical protein LOC100135106Uncharacterized proteinUncharacterized proteinAcetylCholine ReceptorUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinProtein CBR-ACR-3Uncharacterized proteinUncharacterized proteinUncharacterized proteinProtein CBG01449Uncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinGlycine receptor alpha 4b subunitUncharacterized proteinUncharacterized proteinLigand-Gated ion ChannelUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized proteinUncharacterized protein
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FunFam 284: Uncharacterized protein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 0 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

There are 0 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
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