CATH Superfamily 1.10.840.10

Browse Functional Families

ID	Function Family (FunFam) Name	Total Sequences	Structure?	Structural Representative	PDB Sites?	Alignment Diversity (0-100)
1	Rap guanine nucleotide exchange factor GEF	575		-	-	72.3
2	Rap guanine nucleotide exchange factor 4	487	3D	4mh0E05	-	85.7
6	son of sevenless homolog 1 isoform X2	396	3D	6eppS02	-	68.5
3	Ras guanyl-releasing protein 3 isoform 1	392	3D	4l9mA02	-	89.2
4	ras-specific guanine nucleotide-releasing factor 2 isoform X1	349	3D	2ijeS00	-	67.0
5	Ral guanine nucleotide dissociation stimulator isoform 1	347		-	-	72.7
7	SH2 domain containing 3C Predicted	328	3D	3t6gC00	-	83.6
8	Ras-GEF domain-containing family member 1B	286		-	-	72.2
9	rap guanine nucleotide exchange factor 1	206		-	-	90.8
10	ras-specific guanine nucleotide-releasing factor RalGPS1 isoform X1	191	3D	3qxlB00	-	55.7
11	Phosphoinositide phospholipase C	124		-	-	62.0
12	Ral guanine nucleotide dissociation stimulator-like 2	79	3D	4jgwB02	-	45.2
13	Kinase non-catalytic C-lobe domain-containing 1	77		-	-	77.9
14	SH2 domain containing 3A	38		-	-	58.3
15	Uncharacterized protein, isoform A	36		-	-	90.4
16	RASGEF1A isoform 5	32		-	-	68.8
17	Blast:Ral guanine nucleotide dissociation stimulator-like 1	22		-	-	20.4
18	Rap guanine nucleotide exchange factor 5	17		-	-	6.3
20	Phosphoinositide phospholipase C	13		-	-	6.0
19	Guanine nucleotide exchange factor LTE1	13		-	-	73.9
23	Rho GTPase-activating protein	10		-	-	34.9
22	Ral GDS-Like	10		-	-	10.4
21	Cell division cycle-related protein	10		-	-	8.5
24	Rap Guanine nucleotide Exchange Factor homolog	8		-	-	16.0
26	GTP/GDP exchange factor for Rsr1 protein	6		-	-	0.0
25	uncharacterized protein LOC108092584 isoform X2	6		-	-	13.6
28	Cell division control protein 25	3		-	-	9.0
31	Phospholipase C, epsilon 1	3		-	-	3.3
27	Ras family guanine nucleotide exchange factor	3		-	-	7.7
29	Ras guanine nucleotide exchange factor E	3		-	-	63.0
30	SH2 domain-containing 3Cb	3		-	-	1.5
38	Ras guanine nucleotide exchange factor N	2		-	-	39.6
33	Predicted protein	2		-	-	36.2
32	Uncharacterized protein	2		-	-	29.2
36	YALI0F32043p	2		-	-	0.0
35	Drosophila SOS homolog	2		-	-	0.0
37	Son of sevenless homolog	2		-	-	0.0
34	Uncharacterized protein	2		-	-	1.7
51	SH2 domain containing 3Ca	1		-	-	0.0
48	Phosphoinositide phospholipase C	1		-	-	0.0
42	Phosphoinositide phospholipase C	1		-	-	0.0
43	Uncharacterized protein	1		-	-	0.0
41	Cyclic GMP-binding protein C	1		-	-	0.0
47	Phosphoinositide phospholipase C	1		-	-	0.0
45	Cyclic GMP-binding protein D	1		-	-	0.0
50	Uncharacterized protein	1		-	-	0.0
46	Phospholipase C epsilon, putative	1		-	-	0.0
40	Uncharacterized protein	1		-	-	0.0
44	Phosphoinositide phospholipase C	1		-	-	0.0
49	Uncharacterized protein	1		-	-	0.0
39	Protein ste6	1		-	-	0.0

Network disruptions

CATH Superfamily 1.10.840.10

Ras guanine-nucleotide exchange factors catalytic domain

Functional Families

Browse Functional Families