CATH Domain 5ko1A01

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.200	Phosphorylase Kinase; domain 1
	3.30.200.20	Phosphorylase Kinase; domain 1

Domain Context

CATH Clusters

Superfamily	Phosphorylase Kinase; domain 1
Functional Family	Mixed lineage kinase domain-like pseudokinase

Enzyme Information

UniProtKB Entries (1)

MLKL_HUMAN

Homo sapiens

Mixed lineage kinase domain-like protein

PDB Structure

PDB	5KO1
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	ATP-Competitive MLKL Binders Have No Functional Impact on Necroptosis. Ma, B., Marcotte, D., Paramasivam, M., Michelsen, K., Wang, T., Bertolotti-Ciarlet, A., Jones, J.H., Moree, B., Butko, M., Salafsky, J., Sun, X., McKee, T., Silvian, L.F. Plos One