The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Zinc finger, CCCH-type
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 8: zinc finger CCCH domain-containing protein 3

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
SMAD binding GO:0046332
Interacting selectively and non-covalently with a SMAD signaling protein.
2 Q8CHP0 (/IPI) Q8CHP0 (/IPI)
R-SMAD binding GO:0070412
Interacting selectively and non-covalently with a receptor-regulated SMAD signaling protein.
2 Q8CHP0 (/IDA) Q8CHP0 (/IDA)
DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000981
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a RNA polymerase II-transcribed gene to modulate transcription. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units.
1 Q8IXZ2 (/ISM)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q9VSK8 (/IPI)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
MRNA polyadenylation GO:0006378
The enzymatic addition of a sequence of 40-200 adenylyl residues at the 3' end of a eukaryotic mRNA primary transcript.
2 Q8CHP0 (/ISO) Q8CHP0 (/ISO)
MRNA 3'-end processing GO:0031124
Any process involved in forming the mature 3' end of an mRNA molecule.
2 Q8CHP0 (/IDA) Q8CHP0 (/IDA)
Positive regulation of activin receptor signaling pathway GO:0032927
Any process that activates or increases the frequency, rate or extent of the activity of any activin receptor signaling pathway.
2 Q8CHP0 (/IGI) Q8CHP0 (/IGI)
Regulation of mRNA polyadenylation GO:1900363
Any process that modulates the frequency, rate or extent of mRNA polyadenylation.
2 Q8IXZ2 (/IMP) Q9VSK8 (/IMP)
Regulation of mRNA polyadenylation GO:1900363
Any process that modulates the frequency, rate or extent of mRNA polyadenylation.
2 Q8CHP0 (/ISS) Q8CHP0 (/ISS)
Regulation of mRNA export from nucleus GO:0010793
Any process that modulates the frequency, rate or extent of the directed movement of mRNA from the nucleus to the cytoplasm.
1 Q9VSK8 (/IMP)
Nuclear export GO:0051168
The directed movement of substances out of the nucleus.
1 Q9VSK8 (/IMP)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q8IXZ2 (/IDA) Q9VSK8 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q8CHP0 (/ISO) Q8CHP0 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 Q8CHP0 (/ISS) Q8CHP0 (/ISS)
MRNA cleavage and polyadenylation specificity factor complex GO:0005847
A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal.
2 Q8CHP0 (/IDA) Q8CHP0 (/IDA)