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CATH Superfamily 4.10.1000.10

Zinc finger, CCCH-type

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Zinc finger, CCCH-type
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 5: cleavage and polyadenylation specificity factor su...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
 16 O19137 (/IPI) O95639 (/IPI) O95639 (/IPI) O95639 (/IPI) O95639 (/IPI) O95639 (/IPI) O95639 (/IPI) O95639 (/IPI) O95639 (/IPI) O95639 (/IPI)
(6 more)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
 15 O95639 (/HDA) O95639 (/HDA) O95639 (/HDA) O95639 (/HDA) O95639 (/HDA) O95639 (/HDA) O95639 (/HDA) O95639 (/HDA) O95639 (/HDA) O95639 (/HDA)
(5 more)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
 1 Q55CA3 (/ISS)
Endoribonuclease activity GO:0004521
Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.
 1 Q9VPT8 (/IDA)

There are 9 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
MRNA splicing, via spliceosome GO:0000398
The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
 15 O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS)
(5 more)
Termination of RNA polymerase II transcription GO:0006369
The process in which the synthesis of an RNA molecule by RNA polymerase II using a DNA template is completed.
 15 O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS)
(5 more)
TRNA splicing, via endonucleolytic cleavage and ligation GO:0006388
Splicing of tRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons.
 15 O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS)
(5 more)
MRNA export from nucleus GO:0006406
The directed movement of mRNA from the nucleus to the cytoplasm.
 15 O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS)
(5 more)
MRNA 3'-end processing GO:0031124
Any process involved in forming the mature 3' end of an mRNA molecule.
 15 O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS)
(5 more)
Modification by virus of host mRNA processing GO:0046778
Any viral process that interferes with the processing of mRNA in the host cell.
 15 O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS)
(5 more)
MRNA polyadenylation GO:0006378
The enzymatic addition of a sequence of 40-200 adenylyl residues at the 3' end of a eukaryotic mRNA primary transcript.
 2 Q55CA3 (/ISS) Q9VPT8 (/ISS)
Eye photoreceptor cell development GO:0042462
Development of a photoreceptor, a sensory cell in the eye that reacts to the presence of light. They usually contain a pigment that undergoes a chemical change when light is absorbed, thus stimulating a nerve.
 2 F1Q949 (/IMP) Q98881 (/IMP)
MRNA cleavage GO:0006379
Any process in which a pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner.
 1 Q55CA3 (/ISS)

There are 5 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
MRNA cleavage and polyadenylation specificity factor complex GO:0005847
A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal.
 17 O19137 (/ISS) Q55CA3 (/ISS) Q5FVR7 (/ISS) Q5FVR7 (/ISS) Q5FVR7 (/ISS) Q5FVR7 (/ISS) Q5FVR7 (/ISS) Q5FVR7 (/ISS) Q5FVR7 (/ISS) Q5FVR7 (/ISS)
(7 more)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
 15 O95639 (/IDA) O95639 (/IDA) O95639 (/IDA) O95639 (/IDA) O95639 (/IDA) O95639 (/IDA) O95639 (/IDA) O95639 (/IDA) O95639 (/IDA) O95639 (/IDA)
(5 more)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
 15 O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS) O95639 (/TAS)
(5 more)
MRNA cleavage and polyadenylation specificity factor complex GO:0005847
A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal.
 15 O95639 (/IDA) O95639 (/IDA) O95639 (/IDA) O95639 (/IDA) O95639 (/IDA) O95639 (/IDA) O95639 (/IDA) O95639 (/IDA) O95639 (/IDA) O95639 (/IDA)
(5 more)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
 15 O95639 (/IDA) O95639 (/IDA) O95639 (/IDA) O95639 (/IDA) O95639 (/IDA) O95639 (/IDA) O95639 (/IDA) O95639 (/IDA) O95639 (/IDA) O95639 (/IDA)
(5 more)